8FAK

DNA replication fork binding triggers structural changes in the PriA DNA helicase that regulate the PriA-PriB replication restart pathway in E. coli

This is a non-PDB format compatible entry.

Summary for 8FAK

• Entry DOI: 10.2210/pdb8fak/pdb
• EMDB information: 28959
• Descriptor: Primosomal replication protein N, DNA (5'-D(P*CP*AP*GP*AP*CP*TP*CP*AP*TP*TP*TP*AP*GP*CP*CP*CP*TP*TP*AP*TP*CP*CP*G)-3'), Primosomal protein N', ... (6 entities in total)
• Functional Keywords: pria, prib, replication restart, e. coli, helicase-dna complex, helicase/dna
• Biological source: Escherichia coli (strain K12); More
• Total number of polymer chains: 6
• Total formula weight: 133989.76

Authors

Duckworth, A.T.,Ducos, P.L.,McMillan, S.D.,Satyshur, K.A.,Blumenthal, K.H.,Deorio, H.R.,Larson, J.A.,Sandler, S.J.,Grant, T.,Keck, J.L. (deposition date: 2022-11-28, release date: 2023-05-10, Last modification date: 2023-05-24)

• Primary citation: Duckworth, A.T.,Ducos, P.L.,McMillan, S.D.,Satyshur, K.A.,Blumenthal, K.H.,Deorio, H.R.,Larson, J.A.,Sandler, S.J.,Grant, T.,Keck, J.L.; Replication fork binding triggers structural changes in the PriA helicase that govern DNA replication restart in E. coli.; Nat Commun, 14:2725-2725, 2023; PubMed: 37169801; DOI: 10.1038/s41467-023-38144-x

Experimental method

ELECTRON MICROSCOPY (3.22 Å)