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1ELY
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BU of 1ely by Molmil
E. COLI ALKALINE PHOSPHATASE MUTANT (S102C)
分子名称: ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ...
著者Stec, B, Hehir, M, Brennan, C, Nolte, M, Kantrowitz, E.R.
登録日1998-02-10
公開日1998-05-27
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Kinetic and X-ray structural studies of three mutant E. coli alkaline phosphatases: insights into the catalytic mechanism without the nucleophile Ser102.
J.Mol.Biol., 277, 1998
1EW8
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BU of 1ew8 by Molmil
ALKALINE PHOSPHATASE (E.C. 3.1.3.1) COMPLEX WITH PHOSPHONOACETIC ACID
分子名称: ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ...
著者Holtz, K.M, Stec, B, Myers, J.K, Antonelli, S.M, Widlanski, T.S, Kantrowitz, E.R.
登録日2000-04-24
公開日2002-05-01
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Alternate modes of binding in two crystal structures of alkaline phosphatase-inhibitor complexes.
Protein Sci., 9, 2000
1EW2
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CRYSTAL STRUCTURE OF A HUMAN PHOSPHATASE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, PHOSPHATASE, ...
著者Le Du, M.H, Stigbrand, T, Taussig, M.J, Menez, A, Stura, E.A.
登録日2000-04-21
公開日2001-04-04
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Crystal structure of alkaline phosphatase from human placenta at 1.8 A resolution. Implication for a substrate specificity.
J.Biol.Chem., 276, 2001
1ELX
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BU of 1elx by Molmil
E. COLI ALKALINE PHOSPHATASE MUTANT (S102A)
分子名称: ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ...
著者Stec, B, Hehir, M, Brennan, C, Nolte, M, Kantrowitz, E.R.
登録日1998-02-10
公開日1998-05-27
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Kinetic and X-ray structural studies of three mutant E. coli alkaline phosphatases: insights into the catalytic mechanism without the nucleophile Ser102.
J.Mol.Biol., 277, 1998
3CMR
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BU of 3cmr by Molmil
E. coli alkaline phosphatase mutant R166S in complex with phosphate
分子名称: Alkaline phosphatase, MAGNESIUM ION, PHOSPHATE ION, ...
著者O'Brien, P.J, Lassila, J.K, Fenn, T.D, Zalatan, J.G, Herschlag, D.
登録日2008-03-24
公開日2008-07-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Arginine coordination in enzymatic phosphoryl transfer: evaluation of the effect of Arg166 mutations in Escherichia coli alkaline phosphatase
Biochemistry, 47, 2008
3DPC
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BU of 3dpc by Molmil
Structure of E.coli Alkaline Phosphatase Mutant in Complex with a Phosphorylated Peptide
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alkaline phosphatase, PHOSPHATE ION, ...
著者Wang, W.H, Jiang, T.
登録日2008-07-07
公開日2009-06-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Development of a universal phosphorylated peptide-binding protein for simultaneous assay of kinases
Biosens.Bioelectron., 24, 2009
3DYC
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Structure of E322Y Alkaline Phosphatase in Complex with Inorganic Phosphate
分子名称: Alkaline phosphatase, PHOSPHATE ION, ZINC ION
著者Zalatan, J.G, Fenn, T.D, Herschlag, D.
登録日2008-07-25
公開日2008-10-21
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献Comparative Enzymology in the Alkaline Phosphatase Superfamily to Determine the Catalytic Role of an Active-Site Metal Ion.
J.Mol.Biol., 384, 2008
3E2D
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BU of 3e2d by Molmil
The 1.4 A crystal structure of the large and cold-active Vibrio sp. alkaline phosphatase
分子名称: 1,2-ETHANEDIOL, Alkaline phosphatase, MAGNESIUM ION, ...
著者Helland, R, Larsen, R.L, Asgeirsson, B.
登録日2008-08-05
公開日2009-06-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The 1.4 A crystal structure of the large and cold-active Vibrio sp. alkaline phosphatase.
Biochim.Biophys.Acta, 1794, 2009
1ALI
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BU of 1ali by Molmil
ALKALINE PHOSPHATASE MUTANT (H412N)
分子名称: ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ...
著者Ma, L, Tibbitts, T.T, Kantrowitz, E.R.
登録日1995-06-02
公開日1995-11-14
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Escherichia coli alkaline phosphatase: X-ray structural studies of a mutant enzyme (His-412-->Asn) at one of the catalytically important zinc binding sites.
Protein Sci., 4, 1995
1ALK
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BU of 1alk by Molmil
REACTION MECHANISM OF ALKALINE PHOSPHATASE BASED ON CRYSTAL STRUCTURES. TWO METAL ION CATALYSIS
分子名称: ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ...
著者Kim, E.E, Wyckoff, W.
登録日1993-03-03
公開日1994-01-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Reaction mechanism of alkaline phosphatase based on crystal structures. Two-metal ion catalysis.
J.Mol.Biol., 218, 1991
1ALH
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KINETICS AND CRYSTAL STRUCTURE OF A MUTANT E. COLI ALKALINE PHOSPHATASE (ASP-369-->ASN): A MECHANISM INVOLVING ONE ZINC PER ACTIVE SITE
分子名称: ALKALINE PHOSPHATASE, PHOSPHATE ION, SULFATE ION, ...
著者Tibbitts, T.T, Xu, X, Kantrowitz, E.R.
登録日1994-08-23
公開日1995-02-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Kinetics and crystal structure of a mutant Escherichia coli alkaline phosphatase (Asp-369-->Asn): a mechanism involving one zinc per active site.
Protein Sci., 3, 1994
1ALJ
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ALKALINE PHOSPHATASE MUTANT (H412N)
分子名称: ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ...
著者Ma, L, Tibbitts, T.T, Kantrowitz, E.R.
登録日1995-06-02
公開日1995-11-14
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Escherichia coli alkaline phosphatase: X-ray structural studies of a mutant enzyme (His-412-->Asn) at one of the catalytically important zinc binding sites.
Protein Sci., 4, 1995
1ANJ
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ALKALINE PHOSPHATASE (K328H)
分子名称: ALKALINE PHOSPHATASE, PHOSPHATE ION, ZINC ION
著者Murphy, J.E, Tibbitts, T.T, Kantrowitz, E.R.
登録日1995-09-06
公開日1996-01-29
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mutations at positions 153 and 328 in Escherichia coli alkaline phosphatase provide insight towards the structure and function of mammalian and yeast alkaline phosphatases.
J.Mol.Biol., 253, 1995
1ANI
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BU of 1ani by Molmil
ALKALINE PHOSPHATASE (D153H, K328H)
分子名称: ALKALINE PHOSPHATASE, PHOSPHATE ION, ZINC ION
著者Murphy, J.E, Tibbitts, T.T, Kantrowitz, E.R.
登録日1995-09-06
公開日1996-01-29
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mutations at positions 153 and 328 in Escherichia coli alkaline phosphatase provide insight towards the structure and function of mammalian and yeast alkaline phosphatases.
J.Mol.Biol., 253, 1995
1AJD
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BU of 1ajd by Molmil
THREE-DIMENSIONAL STRUCTURE OF THE D153G MUTANT OF E. COLI ALKALINE PHOSPHATASE: A MUTANT WITH WEAKER MAGNESIUM BINDING AND INCREASED CATALYTIC ACTIVITY
分子名称: ALKALINE PHOSPHATASE INTERMEDIATE II OF HOLO ENZYME, MAGNESIUM ION, ZINC ION
著者Dealwis, C.G, Chen, L, Abad-Zapatero, C.
登録日1995-08-18
公開日1995-11-14
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystallographic analysis of reversible metal binding observed in a mutant (Asp153-->Gly) of Escherichia coli alkaline phosphatase.
Biochemistry, 34, 1995
1AJA
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THREE-DIMENSIONAL STRUCTURE OF THE D153G MUTANT OF E. COLI ALKALINE PHOSPHATASE: A MUTANT WITH WEAKER MAGNESIUM BINDING AND INCREASED CATALYTIC ACTIVITY
分子名称: ALKALINE PHOSPHATASE
著者Dealwis, C.G, Chen, L, Abad-Zapatero, C.
登録日1995-08-19
公開日1995-11-14
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystallographic analysis of reversible metal binding observed in a mutant (Asp153-->Gly) of Escherichia coli alkaline phosphatase.
Biochemistry, 34, 1995
1AJC
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THREE-DIMENSIONAL STRUCTURE OF THE D153G MUTANT OF E. COLI ALKALINE PHOSPHATASE: A MUTANT WITH WEAKER MAGNESIUM BINDING AND INCREASED CATALYTIC ACTIVITY
分子名称: ALKALINE PHOSPHATASE, MAGNESIUM ION, ZINC ION
著者Dealwis, C.G, Chen, L, Abad-Zapatero, C.
登録日1995-07-18
公開日1995-11-14
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystallographic analysis of reversible metal binding observed in a mutant (Asp153-->Gly) of Escherichia coli alkaline phosphatase.
Biochemistry, 34, 1995
1AJB
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THREE-DIMENSIONAL STRUCTURE OF THE D153G MUTANT OF E. COLI ALKALINE PHOSPHATASE: A MUTANT WITH WEAKER MAGNESIUM BINDING AND INCREASED CATALYTIC ACTIVITY
分子名称: ALKALINE PHOSPHATASE, MAGNESIUM ION, SULFATE ION, ...
著者Dealwis, C.G, Chen, L, Abad-Zapatero, C.
登録日1995-08-19
公開日1995-11-14
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献3-D structure of the D153G mutant of Escherichia coli alkaline phosphatase: an enzyme with weaker magnesium binding and increased catalytic activity.
Protein Eng., 8, 1995
1HQA
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BU of 1hqa by Molmil
ALKALINE PHOSPHATASE (H412Q)
分子名称: ALKALINE PHOSPHATASE, ZINC ION
著者Ma, L, Kantrowitz, E.R.
登録日1995-11-30
公開日1996-03-08
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Kinetic and X-ray structural studies of a mutant Escherichia coli alkaline phosphatase (His-412-->Gln) at one of the zinc binding sites.
Biochemistry, 35, 1996
1HJK
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ALKALINE PHOSPHATASE MUTANT H331Q
分子名称: ALKALINE PHOSPHATASE, MAGNESIUM ION, SULFATE ION, ...
著者Murphy, J.E, Stec, B, Ma, L, Kantrowitz, E.R.
登録日1997-05-30
公開日1997-10-15
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Trapping and visualization of a covalent enzyme-phosphate intermediate.
Nat.Struct.Biol., 4, 1997
1K7H
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CRYSTAL STRUCTURE OF SHRIMP ALKALINE PHOSPHATASE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALKALINE PHOSPHATASE, MALEIC ACID, ...
著者De Backer, M.E, Mc Sweeney, S, Rasmussen, H.B, Riise, B.W, Lindley, P, Hough, E.
登録日2001-10-19
公開日2002-07-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献The 1.9 A Crystal Structure of Heat-Labile Shrimp Alkaline Phosphatase
J.Mol.Biol., 318, 2002
1KH9
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E. COLI ALKALINE PHOSPHATASE MUTANT (D153GD330N) COMPLEX WITH PHOSPHATE
分子名称: Alkaline phosphatase, MAGNESIUM ION, PHOSPHATE ION, ...
著者Le Du, M.H, Lamoure, C, Muller, B.H, Bulgakov, O.V, Lajeunesse, E.
登録日2001-11-29
公開日2002-03-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Artificial evolution of an enzyme active site: structural studies of three highly active mutants of Escherichia coli alkaline phosphatase.
J.Mol.Biol., 316, 2002
1KHK
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E. COLI ALKALINE PHOSPHATASE MUTANT (D153HD330N)
分子名称: Alkaline Phosphatase, MAGNESIUM ION, ZINC ION
著者Le Du, M.H, Lamoure, C, Muller, B.H, Bulgakov, O.V, Lajeunesse, E, Menez, A, Boulain, J.C.
登録日2001-11-30
公開日2002-03-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Artificial evolution of an enzyme active site: structural studies of three highly active mutants of Escherichia coli alkaline phosphatase.
J.Mol.Biol., 316, 2002
1KH7
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E. COLI ALKALINE PHOSPHATASE MUTANT (D153GD330N)
分子名称: MAGNESIUM ION, SULFATE ION, ZINC ION, ...
著者Le Du, M.H, Lamoure, C, Muller, B.H, Bulgakov, O.V, Lajeunesse, E.
登録日2001-11-29
公開日2002-03-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Artificial evolution of an enzyme active site: structural studies of three highly active mutants of Escherichia coli alkaline phosphatase.
J.Mol.Biol., 316, 2002
1KHL
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E. COLI ALKALINE PHOSPHATASE MUTANT (D153HD330N) COMPLEX WITH PHOSPHATE
分子名称: Alkaline Phosphatase, PHOSPHATE ION, ZINC ION
著者Le Du, M.H, Lamoure, C, Muller, B.H, Bulgakov, O.V, Lajeunesse, E, Menez, A, Boulain, J.C.
登録日2001-11-30
公開日2002-03-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Artificial evolution of an enzyme active site: structural studies of three highly active mutants of Escherichia coli alkaline phosphatase.
J.Mol.Biol., 316, 2002

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