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2BQ0
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14-3-3 Protein Beta (Human)
分子名称: 14-3-3 BETA/ALPHA
著者Yang, X, Elkins, J.M, Fedorov, O, Longman, E.J, Sobott, L, Ball, L.J, Sundstrom, M, Arrowsmith, C, Edwards, A, Doyle, D.A.
登録日2005-04-26
公開日2005-05-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for Protein-Protein Interactions in the 14-3-3 Protein Family.
Proc.Natl.Acad.Sci.USA, 103, 2006
2C1N
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BU of 2c1n by Molmil
Molecular basis for the recognition of phosphorylated and phosphoacetylated histone H3 by 14-3-3
分子名称: 14-3-3 PROTEIN ZETA/DELTA, HISTONE H3 ACETYLPHOSPHOPEPTIDE
著者Welburn, J.P.I, Macdonald, N, Noble, M.E.M, Nguyen, A, Yaffe, M.B, Clynes, D, Moggs, J.G, Orphanides, G, Thomson, S, Edmunds, J.W, Clayton, A.L, Endicott, J.A, Mahadevan, L.C.
登録日2005-09-16
公開日2005-11-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular Basis for the Recognition of Phosphorylated and Phosphoacetylated Histone H3 by 14-3-3.
Mol.Cell, 20, 2005
2C23
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14-3-3 Protein Beta (Human) in complex with exoenzyme S peptide
分子名称: 14-3-3 BETA/ALPHA, EXOENZYME S PEPTIDE
著者Elkins, J.M, Schoch, G.A, Yang, X, Sundstrom, M, Arrowsmith, C, Edwards, A, Doyle, D.A.
登録日2005-09-26
公開日2005-09-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural Basis for Protein-Protein Interactions in the 14-3-3 Protein Family.
Proc.Natl.Acad.Sci.USA, 103, 2006
2C74
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14-3-3 Protein Eta (Human) Complexed to Peptide
分子名称: 14-3-3 PROTEIN ETA, CITRIC ACID, CONSENSUS PEPTIDE MODE 1 FOR 14-3-3 PROTEINS
著者Elkins, J.M, Yang, X, Smee, C.E.A, Johansson, C, Sundstrom, M, Edwards, A, Weigelt, J, Arrowsmith, C, Doyle, D.A.
登録日2005-11-17
公開日2005-12-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for protein-protein interactions in the 14-3-3 protein family.
Proc. Natl. Acad. Sci. U.S.A., 103, 2006
2BTP
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BU of 2btp by Molmil
14-3-3 Protein Theta (Human) Complexed to Peptide
分子名称: 14-3-3 PROTEIN TAU, CONSENSUS PEPTIDE FOR 14-3-3 PROTEINS
著者Elkins, J.M, Johansson, A.C.E, Smee, C, Yang, X, Sundstrom, M, Edwards, A, Arrowsmith, C, Doyle, D.A, Structural Genomics Consortium (SGC)
登録日2005-06-05
公開日2005-06-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for Protein-Protein Interactions in the 14-3-3 Protein Family.
Proc.Natl.Acad.Sci.USA, 103, 2006
2B05
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BU of 2b05 by Molmil
Crystal Structure of 14-3-3 gamma in complex with a phosphoserine peptide
分子名称: 14-3-3 protein gamma, peptide
著者Papagrigoriou, E, Elkins, J, Arrowsmith, C, Zhao, Y, Debreczeni, E.J, Edwards, A, Weigelt, J, Doyle, D, von Delft, F, Turnbull, A, Yang, X.
登録日2005-09-13
公開日2005-10-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal Structure of 14-3-3 gamma in complex with a phosphoserine peptide
TO BE PUBLISHED
6T5F
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Human 14-3-3 sigma fused to the StARD1 peptide including phosphoserine-195
分子名称: 14-3-3 protein sigma, StARD1 peptide
著者Sluchanko, N.N, Tugaeva, K.V, Titterington, J, Antson, A.A.
登録日2019-10-16
公開日2020-11-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Molecular basis for the recognition of steroidogenic acute regulatory protein by the 14-3-3 protein family.
Febs J., 287, 2020
6T80
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Human 14-3-3 sigma fused to the AANAT peptide including phosphoserine-205
分子名称: 14-3-3 protein sigma, AANAT peptide
著者Sluchanko, N.N, Tugaeva, K.V, Titterington, J, Antson, A.A.
登録日2019-10-23
公開日2020-11-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Human 14-3-3 sigma fused to the AANAT peptide including phosphoserine-205
To Be Published
6TM7
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Human 14-3-3 sigma isoform in complex with PLP
分子名称: 14-3-3 protein sigma, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION
著者Tassone, G, Pozzi, C, Mangani, S.
登録日2019-12-03
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction.
Acs Chem.Biol., 15, 2020
6TWZ
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14-3-3 sigma complexed with a phosphorylated 16E6 peptide
分子名称: 14-3-3 protein sigma, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, D(-)-TARTARIC ACID, ...
著者Gogl, G, Cousido-Siah, A, Sluchanko, N.N, Trave, G.
登録日2020-01-13
公開日2020-05-06
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study.
Structure, 28, 2020
6TJM
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Crystal structure of an Estrogen Receptor alpha 8-mer phosphopeptide in complex with 14-3-3sigma stabilized by Pyrrolidone1
分子名称: 14-3-3 protein sigma, 5-[(2~{R})-2-(4-nitrophenyl)-4-oxidanyl-5-oxidanylidene-3-(phenylcarbonyl)-2~{H}-pyrrol-1-yl]-2-oxidanyl-benzoic acid, C-terminal phosphopeptide of human estrogen receptor alpha, ...
著者Andrei, S.A, Bosica, F, Ottmann, C, O'Mahony, G.
登録日2019-11-26
公開日2020-04-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Design of Drug-Like Protein-Protein Interaction Stabilizers Guided By Chelation-Controlled Bioactive Conformation Stabilization.
Chemistry, 26, 2020
6TLF
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human 14-3-3 sigma isoform in complex with IMP
分子名称: 14-3-3 protein sigma, INOSINIC ACID, SULFATE ION
著者Tassone, G, Pozzi, C, Mangani, S.
登録日2019-12-02
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction.
Acs Chem.Biol., 15, 2020
6W0L
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BU of 6w0l by Molmil
Henipavirus W protein interacts with 14-3-3 to modulate host gene expression
分子名称: 14-3-3 protein sigma, CALCIUM ION, Phosphorylated W peptide
著者Edwards, M, Hoad, M, Tsimbalyuk, S, Menicucci, A, Messaoudi, I, Forwood, J, Basler, C.
登録日2020-03-01
公開日2020-04-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Henipavirus W Proteins Interact with 14-3-3 To Modulate Host Gene Expression.
J.Virol., 94, 2020
6T5H
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BU of 6t5h by Molmil
Human 14-3-3 sigma fused to the StARD1 peptide including phosphoserine-57
分子名称: 14-3-3 protein sigma,Steroidogenic acute regulatory protein, mitochondrial, IMIDAZOLE, ...
著者Sluchanko, N.N, Tugaeva, K.V, Titterington, J, Antson, A.A.
登録日2019-10-16
公開日2020-11-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Molecular basis for the recognition of steroidogenic acute regulatory protein by the 14-3-3 protein family.
Febs J., 287, 2020
6A5Q
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BU of 6a5q by Molmil
Structure of 14-3-3 beta in complex with TFEB 14-3-3 binding motif
分子名称: 14-3-3 protein beta/alpha, MALONIC ACID, TFEB pS211-peptide
著者Xu, Y, Ren, J.Q, Feng, W.
登録日2018-06-25
公開日2019-02-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献YWHA/14-3-3 proteins recognize phosphorylated TFEB by a noncanonical mode for controlling TFEB cytoplasmic localization.
Autophagy, 15, 2019
6A5S
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Structure of 14-3-3 gamma in complex with TFEB 14-3-3 binding motif
分子名称: 14-3-3 protein gamma, MAGNESIUM ION, SODIUM ION, ...
著者Xu, Y, Ren, J.Q, Feng, W.
登録日2018-06-25
公開日2019-02-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献YWHA/14-3-3 proteins recognize phosphorylated TFEB by a noncanonical mode for controlling TFEB cytoplasmic localization.
Autophagy, 15, 2019
6BCR
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BU of 6bcr by Molmil
Complex of 14-3-3 theta with an IRSp53 peptide phosphorylated at T340
分子名称: 1,2-ETHANEDIOL, 14-3-3 protein theta, DI(HYDROXYETHYL)ETHER, ...
著者Kast, D.J, Dominguez, R.
登録日2017-10-20
公開日2018-10-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.986 Å)
主引用文献Mechanism of IRSp53 inhibition by 14-3-3.
Nat Commun, 10, 2019
6BD2
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BU of 6bd2 by Molmil
Complex of 14-3-3 theta with an IRSp53 peptide doubly-phosphorylated at T340 and S366
分子名称: 1,2-ETHANEDIOL, 14-3-3 protein theta, DI(HYDROXYETHYL)ETHER, ...
著者Kast, D.J, Dominguez, R.
登録日2017-10-20
公開日2018-10-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Mechanism of IRSp53 inhibition by 14-3-3.
Nat Commun, 10, 2019
6BCY
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Complex of 14-3-3 theta with an IRSp53 peptide phosphorylated at T360
分子名称: 14-3-3 protein theta, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DI(HYDROXYETHYL)ETHER, ...
著者Kast, D.J, Dominguez, R.
登録日2017-10-20
公開日2018-10-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mechanism of IRSp53 inhibition by 14-3-3.
Nat Commun, 10, 2019
6BD1
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Complex of 14-3-3 theta with an IRSp53 peptide phosphorylated at S366
分子名称: 14-3-3 protein theta, DI(HYDROXYETHYL)ETHER, Insulin receptor substrate protein of 53 kDa, ...
著者Kast, D.J, Dominguez, R.
登録日2017-10-20
公開日2018-10-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Mechanism of IRSp53 inhibition by 14-3-3.
Nat Commun, 10, 2019
6BYJ
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Structure of human 14-3-3 gamma bound to O-GlcNAc peptide
分子名称: 14-3-3 protein gamma, 2-acetamido-2-deoxy-beta-D-glucopyranose, TSTTATPPVSQASSTTTSTW O-GlcNac peptide
著者Schumacher, M.A.
登録日2017-12-20
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins.
Proc.Natl.Acad.Sci.USA, 115, 2018
6BYK
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Structure of 14-3-3 beta/alpha bound to O-ClcNAc peptide
分子名称: 14-3-3 protein beta/alpha, 2-acetamido-2-deoxy-beta-D-glucopyranose, ATPPVSQASSTT O-GlcNac peptide
著者Schumacher, M.A.
登録日2017-12-20
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins.
Proc.Natl.Acad.Sci.USA, 115, 2018
6BYL
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Structure of 14-3-3 gamma bound to O-GlcNAcylated thr peptide
分子名称: 14-3-3 protein gamma, 2-acetamido-2-deoxy-beta-D-glucopyranose, TSASTTVPVTTATTTTTSTW O-GlcNac peptide
著者Schumacher, M.A.
登録日2017-12-20
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins.
Proc.Natl.Acad.Sci.USA, 115, 2018
6BQT
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BU of 6bqt by Molmil
Complex of 14-3-3 theta with an IRSp53 peptide doubly-phosphorylated at T340 and T360
分子名称: 1,2-ETHANEDIOL, 14-3-3 protein theta, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ...
著者Kast, D.J, Dominguez, R.
登録日2017-11-28
公開日2018-12-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanism of IRSp53 inhibition by 14-3-3.
Nat Commun, 10, 2019
6BZD
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Structure of 14-3-3 gamma R57E mutant bound to GlcNAcylated peptide
分子名称: 14-3-3 protein gamma, 2-acetamido-2-deoxy-beta-D-glucopyranose, GlcNAcylated peptide
著者Schumacher, M.A.
登録日2017-12-22
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018

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