1Q04
 
 | | Crystal structure of FGF-1, S50E/V51N | | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1 | | Authors: | Kim, J, Blaber, M. | | Deposit date: | 2003-07-15 | | Release date: | 2004-07-27 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor
Protein Sci., 14, 2005
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1Q1U
 | | Crystal structure of human FHF1b (FGF12b) | | Descriptor: | SULFATE ION, fibroblast growth factor homologous factor 1 | | Authors: | Olsen, S.K, Garbi, M, Zampieri, N, Eliseenkova, A.V, Ornitz, D.M, Goldfarb, M, Mohammadi, M. | | Deposit date: | 2003-07-22 | | Release date: | 2003-08-05 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs
J.Biol.Chem., 278, 2003
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1RG8
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1RY7
 | | Crystal Structure of the 3 Ig form of FGFR3c in complex with FGF1 | | Descriptor: | Fibroblast growth factor receptor 3, Heparin-binding growth factor 1 | | Authors: | Olsen, S.K, Ibrahimi, O.A, Raucci, A, Zhang, F, Eliseenkova, A.V, Yayon, A, Basilico, C, Linhardt, R.J, Schlessinger, J, Mohammadi, M. | | Deposit date: | 2003-12-19 | | Release date: | 2004-02-10 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity.
Proc.Natl.Acad.Sci.Usa, 101, 2004
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1YTO
 | | Crystal Structure of Gly19 deletion Mutant of Human Acidic Fibroblast Growth Factor | | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION | | Authors: | Lee, J, Blaber, M. | | Deposit date: | 2005-02-10 | | Release date: | 2006-01-24 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Conversion of type I 4:6 to 3:5 beta-turn types in human acidic fibroblast growth factor: Effects upon structure, stability, folding, and mitogenic function.
Proteins, 62, 2006
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1Z2V
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1Z4S
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2AQZ
 | | Crystal structure of FGF-1, S17T/N18T/G19 deletion mutant | | Descriptor: | Heparin-binding growth factor 1, SULFATE ION | | Authors: | Lee, J, Blaber, M. | | Deposit date: | 2005-08-18 | | Release date: | 2006-02-07 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Conversion of type I 4:6 to 3:5 beta-turn types in human acidic fibroblast growth factor: Effects upon structure, stability, folding, and mitogenic function.
Proteins, 62, 2006
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2ERM
 | | Solution structure of a biologically active human FGF-1 monomer, complexed to a hexasaccharide heparin-analogue | | Descriptor: | 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-acetamido-2-deoxy-6-O-sulfo-alpha-D-glucopyranose-(1-4)-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, Heparin-binding growth factor 1, ISOPROPYL ALCOHOL | | Authors: | Canales, A, Lozano, R, Nieto, P.M, Martin-Lomas, M, Gimenez-Gallego, G, Jimenez-Barbero, J. | | Deposit date: | 2005-10-25 | | Release date: | 2006-10-03 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of a human FGF-1 monomer, activated by a hexasaccharide heparin-analogue.
Febs J., 273, 2006
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2FDB
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2HWA
 | | Crystal structure of Lys12Thr/Cys117Val mutant of human acidic fibroblast growth factor at 1.65 angstrom resolution. | | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION | | Authors: | Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M. | | Deposit date: | 2006-08-01 | | Release date: | 2007-06-12 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
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2HW9
 | | Crystal structure of Lys12Cys/Cys117Val mutant of human acidic fibroblast Growth factor at 1.60 angstrom resolution. | | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION | | Authors: | Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M. | | Deposit date: | 2006-08-01 | | Release date: | 2007-06-12 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
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2HWM
 | | Crystal structure of Lys12Val/Cys117Val mutant of human acidic fibroblast growth factor at 1.60 angstrom resolution | | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1 | | Authors: | Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M. | | Deposit date: | 2006-08-01 | | Release date: | 2007-06-12 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
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2HZ9
 | | Crystal structure of Lys12Val/Asn95Val/Cys117Val mutant of human acidic fibroblast growth factor at 1.70 angstrom resolution. | | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION | | Authors: | Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M. | | Deposit date: | 2006-08-08 | | Release date: | 2007-06-19 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Spackling the Crack: Stabilizing Human Fibroblast Growth Factor-1 by Targeting the N and C terminus beta-Strand Interactions
J.Mol.Biol., 371, 2007
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2J3P
 | | crystal structure of rat FGF1 at 1.4 A | | Descriptor: | HEPARIN-BINDING GROWTH FACTOR 1, SULFATE ION | | Authors: | Kulahin, N, Kristensen, O, Berezin, V, Gajhede, M, Bock, E. | | Deposit date: | 2006-08-22 | | Release date: | 2007-02-13 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structure of Rat Acidic Fibroblast Growth Factor at 1.4 A Resolution.
Acta Crystallogr.,Sect.F, 63, 2007
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2NTD
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2P23
 | | Crystal structure of human FGF19 | | Descriptor: | Fibroblast growth factor 19 | | Authors: | Mohammadi, M. | | Deposit date: | 2007-03-06 | | Release date: | 2007-04-10 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members.
Mol.Cell.Biol., 27, 2007
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2UUS
 | | Crystal structure of the rat FGF1-sucrose octasulfate (SOS) complex. | | Descriptor: | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, HEPARIN-BINDING GROWTH FACTOR 1 | | Authors: | Kulahin, N, Kiselyov, V, Kochoyan, A, Kristensen, O, Berezin, V, Bock, E, Gajhede, M. | | Deposit date: | 2007-03-07 | | Release date: | 2008-05-13 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Dimerization Effect of Sucrose Octasulfate on Rat Fgf1.
Acta Crystallogr.,Sect.F, 64, 2008
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2P39
 | | Crystal structure of human FGF23 | | Descriptor: | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, Fibroblast growth factor 23 | | Authors: | Mohammadi, M. | | Deposit date: | 2007-03-08 | | Release date: | 2007-04-10 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members.
Mol.Cell.Biol., 27, 2007
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2Q9X
 | | Crystal structure of highly stable mutant Q40P/S47I/H93G of human fibroblast growth factor-1 | | Descriptor: | GLYCEROL, Heparin-binding growth factor 1 | | Authors: | Szlachcic, A, Zakrzewska, M, Krowarsch, D, Os, V, Helland, R, Otlewski, J. | | Deposit date: | 2007-06-14 | | Release date: | 2008-07-01 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of highly stable mutant Q40P/S47I/H93G of human fibroblast growth factor-1
To be Published
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3B9U
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3BAG
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3BA5
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3BAD
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3BA4
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