2HW9
Crystal structure of Lys12Cys/Cys117Val mutant of human acidic fibroblast Growth factor at 1.60 angstrom resolution.
Summary for 2HW9
Entry DOI | 10.2210/pdb2hw9/pdb |
Related | 1JQZ |
Descriptor | Heparin-binding growth factor 1, SULFATE ION, FORMIC ACID, ... (4 entities in total) |
Functional Keywords | beta-trefoil, hormone-growth factor complex, hormone/growth factor |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P05230 |
Total number of polymer chains | 2 |
Total formula weight | 33643.60 |
Authors | Dubey, V.K.,Lee, J.,Somasundaram, T.,Blaber, M. (deposition date: 2006-08-01, release date: 2007-06-12, Last modification date: 2023-08-30) |
Primary citation | Dubey, V.K.,Lee, J.,Somasundaram, T.,Blaber, S.,Blaber, M. Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions. J.Mol.Biol., 371:256-268, 2007 Cited by PubMed: 17570396DOI: 10.1016/j.jmb.2007.05.065 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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