1RY7
Crystal Structure of the 3 Ig form of FGFR3c in complex with FGF1
Summary for 1RY7
Entry DOI | 10.2210/pdb1ry7/pdb |
Related | 1DJS 1EVT 1NUN |
Descriptor | Heparin-binding growth factor 1, Fibroblast growth factor receptor 3 (2 entities in total) |
Functional Keywords | fgf-fgfr complex; beta trefoil; ig domain, growth factor-growth factor receptor complex, growth factor/growth factor receptor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P05230 Membrane; Single-pass type I membrane protein: P22607 |
Total number of polymer chains | 2 |
Total formula weight | 53777.13 |
Authors | Olsen, S.K.,Ibrahimi, O.A.,Raucci, A.,Zhang, F.,Eliseenkova, A.V.,Yayon, A.,Basilico, C.,Linhardt, R.J.,Schlessinger, J.,Mohammadi, M. (deposition date: 2003-12-19, release date: 2004-02-10, Last modification date: 2023-08-23) |
Primary citation | Olsen, S.K.,Ibrahimi, O.A.,Raucci, A.,Zhang, F.,Eliseenkova, A.V.,Yayon, A.,Basilico, C.,Linhardt, R.J.,Schlessinger, J.,Mohammadi, M. Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity. Proc.Natl.Acad.Sci.Usa, 101:935-940, 2004 Cited by PubMed: 14732692DOI: 10.1073/pnas.0307287101 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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