1NZK
 
 | | Crystal Structure of a Multiple Mutant (L44F, L73V, V109L, L111I, C117V) of Human Acidic Fibroblast Growth Factor | | Descriptor: | Acidic Fibroblast Growth Factor, FORMIC ACID, SULFATE ION | | Authors: | Brych, S.R, Kim, J, Logan, T.M, Blaber, M. | | Deposit date: | 2003-02-18 | | Release date: | 2004-03-02 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Accommodation of a highly symmetric core within a symmetric protein superfold.
Protein Sci., 12, 2003
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1P63
 | | Human Acidic Fibroblast Growth Factor. 140 Amino Acid Form with Amino Terminal His Tag and Leu111 Replaced with Ile (L111I) | | Descriptor: | ACIDIC FIBROBLAST GROWTH FACTOR, FORMIC ACID, SULFATE ION | | Authors: | Brych, S.R, Kim, J, Logan, T.M, Blaber, M. | | Deposit date: | 2003-04-28 | | Release date: | 2004-05-11 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Accommodation of a highly symmetric core within a symmetric protein
superfold
Protein Sci., 12, 2003
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1Q03
 | | Crystal structure of FGF-1, S50G/V51G mutant | | Descriptor: | Heparin-binding growth factor 1 | | Authors: | Kim, J, Blaber, M. | | Deposit date: | 2003-07-15 | | Release date: | 2004-07-27 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor
Protein Sci., 14, 2005
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1Q04
 | | Crystal structure of FGF-1, S50E/V51N | | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1 | | Authors: | Kim, J, Blaber, M. | | Deposit date: | 2003-07-15 | | Release date: | 2004-07-27 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor
Protein Sci., 14, 2005
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1PWA
 | | Crystal structure of Fibroblast Growth Factor 19 | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Fibroblast growth factor-19, GLYCEROL, ... | | Authors: | Harmer, N.J, Pellegrini, L, Chirgadze, D, Fernandez-Recio, J, Blundell, T.L. | | Deposit date: | 2003-07-01 | | Release date: | 2004-01-27 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | The crystal structure of fibroblast growth factor (FGF) 19 reveals novel features of the FGF family and offers a structural basis for its unusual receptor affinity.
Biochemistry, 43, 2004
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1Q1U
 | | Crystal structure of human FHF1b (FGF12b) | | Descriptor: | SULFATE ION, fibroblast growth factor homologous factor 1 | | Authors: | Olsen, S.K, Garbi, M, Zampieri, N, Eliseenkova, A.V, Ornitz, D.M, Goldfarb, M, Mohammadi, M. | | Deposit date: | 2003-07-22 | | Release date: | 2003-08-05 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs
J.Biol.Chem., 278, 2003
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4OEE
 | | Crystal Structure Analysis of FGF2-Disaccharide (S3I2) complex | | Descriptor: | 2-deoxy-3-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-1-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid, Fibroblast growth factor 2 | | Authors: | Li, Y.C, Hsiao, C.D. | | Deposit date: | 2014-01-13 | | Release date: | 2014-07-09 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Interactions that influence the binding of synthetic heparan sulfate based disaccharides to fibroblast growth factor-2.
Acs Chem.Biol., 9, 2014
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4Q9G
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4QC4
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4QBC
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4QBV
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4Q9P
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4Q91
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4OEF
 | | Crystal Structure Analysis of FGF2-Disaccharide (S6I2) complex | | Descriptor: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-1-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid, Fibroblast growth factor 2 | | Authors: | Li, Y.C, Hsiao, C.D. | | Deposit date: | 2014-01-13 | | Release date: | 2014-07-09 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Interactions that influence the binding of synthetic heparan sulfate based disaccharides to fibroblast growth factor-2.
Acs Chem.Biol., 9, 2014
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2J3P
 | | crystal structure of rat FGF1 at 1.4 A | | Descriptor: | HEPARIN-BINDING GROWTH FACTOR 1, SULFATE ION | | Authors: | Kulahin, N, Kristensen, O, Berezin, V, Gajhede, M, Bock, E. | | Deposit date: | 2006-08-22 | | Release date: | 2007-02-13 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structure of Rat Acidic Fibroblast Growth Factor at 1.4 A Resolution.
Acta Crystallogr.,Sect.F, 63, 2007
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2K43
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2HZ9
 | | Crystal structure of Lys12Val/Asn95Val/Cys117Val mutant of human acidic fibroblast growth factor at 1.70 angstrom resolution. | | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION | | Authors: | Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M. | | Deposit date: | 2006-08-08 | | Release date: | 2007-06-19 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Spackling the Crack: Stabilizing Human Fibroblast Growth Factor-1 by Targeting the N and C terminus beta-Strand Interactions
J.Mol.Biol., 371, 2007
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4QAL
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4QO3
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2HWA
 | | Crystal structure of Lys12Thr/Cys117Val mutant of human acidic fibroblast growth factor at 1.65 angstrom resolution. | | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION | | Authors: | Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M. | | Deposit date: | 2006-08-01 | | Release date: | 2007-06-12 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
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2HW9
 | | Crystal structure of Lys12Cys/Cys117Val mutant of human acidic fibroblast Growth factor at 1.60 angstrom resolution. | | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION | | Authors: | Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M. | | Deposit date: | 2006-08-01 | | Release date: | 2007-06-12 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
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2HWM
 | | Crystal structure of Lys12Val/Cys117Val mutant of human acidic fibroblast growth factor at 1.60 angstrom resolution | | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1 | | Authors: | Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M. | | Deposit date: | 2006-08-01 | | Release date: | 2007-06-12 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
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2K8R
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1DZD
 | | High resolution structure of acidic fibroblast growth factor (27-154), 24 NMR structures | | Descriptor: | ACIDIC FIBROBLAST GROWTH FACTOR | | Authors: | Lozano, R.M, Pineda-Lucena, A, Gonzalez, C, Jimenez, M.A, Cuevas, P, Redondo-Horcajo, M, Sanz, J.M, Rico, M, Gimenez-Gallego, G. | | Deposit date: | 2000-02-24 | | Release date: | 2000-03-16 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | 1H-NMR Structural Characterization of a Non Mitogenic, Vasodilatory, Ischemia-Protector and Neuromodulatory Acidic Fibroblast Growth Factor
Biochemistry, 39, 2000
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1DZC
 | | High resolution structure of acidic fibroblast growth factor. Mutant FGF-4-ALA-(24-154), 24 NMR structures | | Descriptor: | FIBROBLAST GROWTH FACTOR 1 | | Authors: | Lozano, R.M, Pineda-Lucena, A, Gonzalez, C, Jimenez, M.A, Cuevas, P, Redondo-Horcajo, M, Sanz, J.M, Rico, M, Gimenez-Gallego, G. | | Deposit date: | 2000-02-24 | | Release date: | 2000-03-16 | | Last modified: | 2013-05-15 | | Method: | SOLUTION NMR | | Cite: | 1H-NMR Structural Characterization of a Non Mitogenic, Vasodilatory, Ischemia-Protector and Neuromodulatory Acidic Fibroblast Growth Factor
Biochemistry, 39, 2000
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