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1PWA

Crystal structure of Fibroblast Growth Factor 19

Summary for 1PWA
Entry DOI10.2210/pdb1pwa/pdb
DescriptorFibroblast growth factor-19, SULFATE ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total)
Functional Keywordsbeta trefoil, disulphide bonds, hormone-growth factor complex, hormone/growth factor
Biological sourceHomo sapiens (human)
Cellular locationSecreted: O95750
Total number of polymer chains1
Total formula weight18426.97
Authors
Harmer, N.J.,Pellegrini, L.,Chirgadze, D.,Fernandez-Recio, J.,Blundell, T.L. (deposition date: 2003-07-01, release date: 2004-01-27, Last modification date: 2023-08-16)
Primary citationHarmer, N.J.,Pellegrini, L.,Chirgadze, D.,Fernandez-Recio, J.,Blundell, T.L.
The crystal structure of fibroblast growth factor (FGF) 19 reveals novel features of the FGF family and offers a structural basis for its unusual receptor affinity.
Biochemistry, 43:629-640, 2004
Cited by
PubMed: 14730967
DOI: 10.1021/bi035320k
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.3 Å)
Structure validation

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