5W13
 
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5W12
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5WAD
 | | ADC-7 in complex with boronic acid transition state inhibitor CR161 | | 分子名称: | Beta-lactamase, PHOSPHATE ION, phosphonooxy-[[[6-(1~{H}-1,2,3,4-tetrazol-5-yl)pyridin-3-yl]sulfonylamino]methyl]borinic acid | | 著者 | Powers, R.A, Wallar, B.J. | | 登録日 | 2017-06-26 | | 公開日 | 2017-12-06 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Structure-Based Analysis of Boronic Acids as Inhibitors of Acinetobacter-Derived Cephalosporinase-7, a Unique Class C beta-Lactamase.
ACS Infect Dis, 4, 2018
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5ZFL
 | | Crystal structure of beta-lactamase PenP mutant E166Y | | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-lactamase | | 著者 | Pan, X, Zhao, Y. | | 登録日 | 2018-03-06 | | 公開日 | 2019-03-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The hydrolytic water molecule of Class A beta-lactamase relies on the acyl-enzyme intermediate ES* for proper coordination and catalysis.
Sci Rep, 10, 2020
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5ZG6
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5ZH8
 | | Crystal Structure of FmtA from Staphylococcus aureus at 2.58 A | | 分子名称: | GLYCEROL, Protein FmtA | | 著者 | Dalal, V, Kumar, P, Golemi-Kotra, D, Kumar, P. | | 登録日 | 2018-03-12 | | 公開日 | 2019-07-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Repurposing an Ancient Protein Core Structure: Structural Studies on FmtA, a Novel Esterase of Staphylococcus aureus.
J.Mol.Biol., 431, 2019
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5ZFT
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5TGF
 | | Crystal structure of putative beta-lactamase from Bacteroides dorei DSM 17855 | | 分子名称: | CALCIUM ION, GLYCEROL, Uncharacterized protein | | 著者 | Nocek, B, Hatzos-Skintges, C, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2016-09-27 | | 公開日 | 2016-10-26 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Crystal structure of a beta-lactamase from Bacteroides dorei DSM 17855
To Be Published
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3RJU
 | | Crystal Structure of Beta-lactamase/D-alanine Carboxypeptidase from Yersinia pestis complexed with citrate | | 分子名称: | Beta-lactamase/D-alanine Carboxypeptidase, CITRIC ACID, GLYCEROL | | 著者 | Kim, Y, Zhou, M, Gu, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2011-04-15 | | 公開日 | 2011-04-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal Structure of Beta-lactamase/D-alanine Carboxypeptidase from Yersinia pestis complexed with citrate
To be Published
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3S22
 | | AMP-C BETA-LACTAMASE (PSEUDOMONAS AERUGINOSA) in complex with an inhibitor | | 分子名称: | Beta-lactamase, CHLORIDE ION, [(2S,3R)-2-formyl-1-{[4-(methylamino)butyl]carbamoyl}pyrrolidin-3-yl]sulfamic acid | | 著者 | Scapin, G, Lu, J, Fitzgerald, P.M.D, Sharma, N. | | 登録日 | 2011-05-16 | | 公開日 | 2011-06-29 | | 最終更新日 | 2013-06-26 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Side chain SAR of bicyclic Beta-lactamase inhibitors (BLIs). 2. N-Alkylated and open chain analogs of MK-8712
Bioorg.Med.Chem.Lett., 21, 2011
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3PTE
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3SH7
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3S1Y
 | | AMP-C BETA-LACTAMASE (PSEUDOMONAS AERUGINOSA) in complex with a beta-lactamase inhibitor | | 分子名称: | Beta-lactamase, CHLORIDE ION, ISOPROPYL ALCOHOL, ... | | 著者 | Scapin, G, Lu, J, Fitzgerald, P.M.D, Sharma, N. | | 登録日 | 2011-05-16 | | 公開日 | 2011-06-29 | | 最終更新日 | 2013-06-26 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Side chain SAR of bicyclic Beta-lactamase inhibitors (BLIs). 2. N-Alkylated and open chain analogs of MK-8712
Bioorg.Med.Chem.Lett., 21, 2011
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3S4X
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3SH9
 | | Crystal structure of fluorophore-labeled beta-lactamase PenP in complex with cefotaxime | | 分子名称: | 1-[6-(dimethylamino)naphthalen-2-yl]ethanone, Beta-lactamase, CEFOTAXIME, ... | | 著者 | Wong, W.-T, Zhao, Y.-X, Leung, Y.-C. | | 登録日 | 2011-06-16 | | 公開日 | 2011-07-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Increased structural flexibility at the active site of a fluorophore-conjugated beta-lactamase distinctively impacts its binding toward diverse cephalosporin antibiotics
J.Biol.Chem., 286, 2011
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3SH8
 | | Crystal structure of fluorophore-labeled beta-lactamase PenP in complex with cephaloridine | | 分子名称: | 5-METHYL-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, Beta-lactamase | | 著者 | Wong, W.-T, Zhao, Y.-X, Leung, Y.-C. | | 登録日 | 2011-06-16 | | 公開日 | 2011-07-27 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Increased structural flexibility at the active site of a fluorophore-conjugated beta-lactamase distinctively impacts its binding toward diverse cephalosporin antibiotics
J.Biol.Chem., 286, 2011
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3SOI
 | | Crystallographic structure of Bacillus licheniformis beta-lactamase W210F/W229F/W251F at 1.73 angstrom resolution | | 分子名称: | Beta-lactamase, CITRIC ACID | | 著者 | Acierno, J.P, Capaldi, S, Risso, V.A, Monaco, H.L, Ermacora, M.R. | | 登録日 | 2011-06-30 | | 公開日 | 2011-12-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.729 Å) | | 主引用文献 | X-ray evidence of a native state with increased compactness populated by tryptophan-less B. licheniformis beta-lactamase.
Protein Sci., 21, 2012
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4BLM
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4GB7
 | | Putative 6-aminohexanoate-dimer hydrolase from Bacillus anthracis | | 分子名称: | 1,2-ETHANEDIOL, 6-aminohexanoate-dimer hydrolase, NITRATE ION | | 著者 | Osipiuk, J, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2012-07-26 | | 公開日 | 2012-08-08 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Putative 6-aminohexanoate-dimer hydrolase from Bacillus anthracis.
To be Published
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4HEF
 | | Structure of avibactam bound to Pseudomonas aeruginosa AmpC | | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase, GLYCEROL | | 著者 | Lahiri, S.D. | | 登録日 | 2012-10-03 | | 公開日 | 2013-06-05 | | 最終更新日 | 2020-09-16 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Structural Insight into Potent Broad-Spectrum Inhibition with Reversible Recyclization Mechanism: Avibactam in Complex with CTX-M-15 and Pseudomonas aeruginosa AmpC beta-Lactamases
Antimicrob.Agents Chemother., 57, 2013
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4GZB
 | | Crystal structure of native AmpC beta-lactamase from Pseudomonas aeruginosa PAO1 | | 分子名称: | 1,2-ETHANEDIOL, Beta-lactamase | | 著者 | Benvenuti, M, De Luca, F, Docquier, J.D, Mangani, S. | | 登録日 | 2012-09-06 | | 公開日 | 2013-04-10 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Structural insight into potent broad-spectrum inhibition with reversible recyclization mechanism: avibactam in complex with CTX-M-15 and Pseudomonas aeruginosa AmpC beta-lactamases
Antimicrob.Agents Chemother., 57, 2013
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4E3J
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4E3M
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4IVK
 | | Crystal structure of a fammily VIII carboxylesterase in a complex with cephalothin. | | 分子名称: | CEPHALOTHIN GROUP, Carboxylesterases, SULFATE ION | | 著者 | An, Y.J, Kim, M.-K, Jeong, C.-S, Cha, S.-S. | | 登録日 | 2013-01-23 | | 公開日 | 2013-06-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for the beta-lactamase activity of EstU1, a family VIII carboxylesterase.
Proteins, 81, 2013
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4E3O
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