PDB: 277 件ウェブページステータス検索Chemie searchBIRD

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5UHC	Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 3nt RNA in complex with Rifampin 分子名称: DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2017-01-11 公開日 2017-04-12 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (3.796 Å) 主引用文献 Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
6WMT	F. tularensis RNAPs70-(MglA-SspA)-ppGpp-PigR-iglA DNA complex 分子名称: DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ... 著者 Travis, B.A, Brennan, R.G, Schumacher, M.A. 登録日 2020-04-21 公開日 2020-11-11 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.43 Å) 主引用文献 Structural Basis for Virulence Activation of Francisella tularensis. Mol.Cell, 81, 2021
6WOX	Thermus thermophilus RNA polymerase initially transcribing complex with 2'dCTP 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*GP*CP*AP*G)-3'), ... 著者 Shin, Y, Murakami, K.S. 登録日 2020-04-26 公開日 2020-06-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.14 Å) 主引用文献 The mechanism of the nucleo-sugar selection by multi-subunit RNA polymerases. Nat Commun, 12, 2021
6WOY	Thermus thermophilus RNA polymerase initially transcribing complex with 3'dCTP 分子名称: 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*GP*CP*AP*G)-3'), ... 著者 Shin, Y, Murakami, K.S. 登録日 2020-04-26 公開日 2020-06-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The mechanism of the nucleo-sugar selection by multi-subunit RNA polymerases. Nat Commun, 12, 2021
6WMR	F. tularensis RNAPs70-(MglA-SspA)-iglA DNA complex 分子名称: DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ... 著者 Travis, B.A, Brennan, R.G, Schumacher, M.A. 登録日 2020-04-21 公開日 2020-11-11 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.46 Å) 主引用文献 Structural Basis for Virulence Activation of Francisella tularensis. Mol.Cell, 81, 2021
5VO8	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter 分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*CP*TP*GP*AP*TP*GP*CP*AP*CP*C)-3'), DNA (5'-D(P*GP*GP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Murakami, K.S, Shin, Y, Turnbough Jr, C.L, Molodtsov, V. 登録日 2017-05-02 公開日 2017-05-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 X-ray crystal structure of a reiterative transcription complex reveals an atypical RNA extension pathway. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5VT0	Escherichia coli 6S RNA derivative in complex with Escherichia coli RNA polymerase sigma70-holoenzyme 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Chen, J, Darst, S.A. 登録日 2017-05-15 公開日 2017-11-01 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.78 Å) 主引用文献 6S RNA Mimics B-Form DNA to Regulate Escherichia coli RNA Polymerase. Mol. Cell, 68, 2017
5VI5	Structure of Mycobacterium smegmatis transcription initiation complex with a full transcription bubble 分子名称: 1,2-ETHANEDIOL, DNA (44-MER), DNA (49-MER), ... 著者 Darst, S.A, Campbell, E.A, Lilic, M. 登録日 2017-04-14 公開日 2017-07-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.196 Å) 主引用文献 Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures. Nat Commun, 8, 2017
5VSW	X-ray crystal structure of Escherichia coli RNA polymerase and DksA/ppGpp complex 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Murakami, K.S, Molodtsov, V. 登録日 2017-05-12 公開日 2017-06-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (4.295 Å) 主引用文献 Allosteric Effector ppGpp Potentiates the Inhibition of Transcript Initiation by DksA. Mol. Cell, 69, 2018
5VI8	Structure of a mycobacterium smegmatis transcription initiation complex with an upstream-fork promoter fragment 分子名称: 1,2-ETHANEDIOL, DNA (26-MER), DNA (31-MER), ... 著者 Hubin, E.A, Campbell, E.A, Darst, S.A. 登録日 2017-04-14 公開日 2017-04-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures. Nat Commun, 8, 2017
5VOI	X-ray crystal structure of bacterial RNA polymerase and pyrG promoter complex 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Murakami, K.S, Shin, Y, Turnbough Jr, C.L, Molodtsov, V. 登録日 2017-05-02 公開日 2017-05-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 X-ray crystal structure of a reiterative transcription complex reveals an atypical RNA extension pathway. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W1S	X-ray crystal structure of Escherichia coli RNA polymerase and TraR complex 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Murakami, K.S, Molodtsov, V. 登録日 2017-06-04 公開日 2017-06-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.805 Å) 主引用文献 Allosteric Effector ppGpp Potentiates the Inhibition of Transcript Initiation by DksA. Mol. Cell, 69, 2018
5W1T	X-ray crystal structure of Escherichia coli RNA polymerase and DksA complex 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Murakami, K.S, Molodtsov, V. 登録日 2017-06-04 公開日 2017-06-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (4.5 Å) 主引用文献 Allosteric Effector ppGpp Potentiates the Inhibition of Transcript Initiation by DksA. Mol. Cell, 69, 2018
5X21	Crystal structure of Thermus thermophilus transcription initiation complex with GpA and pseudouridimycin (PUM) 分子名称: (1S)-1,4-anhydro-5-[(N-carbamimidoylglycyl-N~2~-hydroxy-L-glutaminyl)amino]-5-deoxy-1-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Zhang, Y, Ebright, R. 登録日 2017-01-29 公開日 2017-07-05 最終更新日 2022-10-12 実験手法 X-RAY DIFFRACTION (3.323 Å) 主引用文献 Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase. Cell, 169, 2017
5X22	Crystal structure of Thermus thermophilus transcription initiation complex with GpA and CMPcPP 分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Zhang, Y, Ebright, R. 登録日 2017-01-29 公開日 2017-07-05 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase. Cell, 169, 2017
3IYD	Three-dimensional EM structure of an intact activator-dependent transcription initiation complex 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, DNA (98-MER), ... 著者 Hudson, B.P, Quispe, J, Lara, S, Kim, Y, Berman, H, Arnold, E, Ebright, R.H, Lawson, C.L. 登録日 2009-08-01 公開日 2009-11-10 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (19.799999 Å) 主引用文献 Three-dimensional EM structure of an intact activator-dependent transcription initiation complex Proc.Natl.Acad.Sci.USA, 106, 2009
8JO2	Structural basis of transcriptional activation by the OmpR/PhoB-family response regulator PmrA 分子名称: DNA (65-MER), DNA-binding transcriptional regulator BasR, DNA-directed RNA polymerase subunit alpha, ... 著者 Lou, Y.-C, Huang, H.-Y, Chen, C, Wu, K.-P. 登録日 2023-06-06 公開日 2023-08-30 最終更新日 2023-10-25 実験手法 ELECTRON MICROSCOPY (2.74 Å) 主引用文献 Structural basis of transcriptional activation by the OmpR/PhoB-family response regulator PmrA. Nucleic Acids Res., 51, 2023
5I2D	Crystal structure of T. thermophilus TTHB099 class II transcription activation complex: TAP-RPo 分子名称: DNA (72-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Feng, Y, Zhang, Y, Ebright, R.H. 登録日 2016-02-08 公開日 2016-06-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (4.405 Å) 主引用文献 Structural basis of transcription activation. Science, 352, 2016
8H3V	Cryo-EM structure of the full transcription activation complex NtcA-NtcB-TAC 分子名称: DNA (125-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Han, S.J, Jiang, Y.L, You, L.L, Shen, L.Q, Wu, X.X, Yang, F, Kong, W.W, Chen, Z.P, Zhang, Y, Zhou, C.Z. 登録日 2022-10-09 公開日 2023-10-04 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 DNA looping mediates cooperative transcription activation. Nat.Struct.Mol.Biol., 31, 2024
8H40	Cryo-EM structure of the transcription activation complex NtcA-TAC 分子名称: DNA (125-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Han, S.J, Jiang, Y.L, You, L.L, Shen, L.Q, Wu, X.X, Yang, F, Kong, W.W, Chen, Z.P, Zhang, Y, Zhou, C.Z. 登録日 2022-10-09 公開日 2023-10-04 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 DNA looping mediates cooperative transcription activation. Nat.Struct.Mol.Biol., 31, 2024
7C97	Cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo) with SspA 分子名称: DNA (63-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Lin, W, Feng, Y. 登録日 2020-06-05 公開日 2020-08-12 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.68 Å) 主引用文献 Structural basis for transcription inhibition by E. coli SspA Nucleic Acids Res., 2020
7DY6	A refined cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo) with SspA 分子名称: DNA (63-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Lin, W. 登録日 2021-01-20 公開日 2021-11-17 実験手法 ELECTRON MICROSCOPY (3.68 Å) 主引用文献 A unique binding between SspA and RNAP beta' NTH across low-GC Gram-negative bacteria facilitates SspA-mediated transcription regulation. Biochem.Biophys.Res.Commun., 583, 2021
6B6H	The cryo-EM structure of a bacterial class I transcription activation complex 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Liu, B, Hong, C, Huang, R, Yu, Z, Steitz, T.A. 登録日 2017-10-02 公開日 2017-11-15 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis of bacterial transcription activation. Science, 358, 2017
6PB4	The E. coli class-II CAP-dependent transcription activation complex with de novo RNA transcript at the state 2 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Liu, B, Shi, W. 登録日 2019-06-13 公開日 2020-03-18 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.35 Å) 主引用文献 Visualization of two architectures in class-II CAP-dependent transcription activation Plos Biol., 18, 2020
6PB5	The E. coli class-II CAP-dependent transcription activation complex at the state 1 architecture 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Liu, B, Shi, W. 登録日 2019-06-13 公開日 2020-03-18 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.52 Å) 主引用文献 Visualization of two architectures in class-II CAP-dependent transcription activation Plos Biol., 18, 2020

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