8BU2
 
 | | Structure of DDB1 bound to DS18-engaged CDK12-cyclin K | | 分子名称: | Cyclin-K, Cyclin-dependent kinase 12, DNA damage-binding protein 1, ... | | 著者 | Kozicka, Z, Kempf, G, Petzold, G, Thoma, N.H. | | 登録日 | 2022-11-30 | | 公開日 | 2023-09-13 | | 最終更新日 | 2024-01-03 | | 実験手法 | X-RAY DIFFRACTION (3.13 Å) | | 主引用文献 | Design principles for cyclin K molecular glue degraders.
Nat.Chem.Biol., 20, 2024
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8BU6
 | | Structure of DDB1 bound to DS55-engaged CDK12-cyclin K | | 分子名称: | Cyclin-K, Cyclin-dependent kinase 12, DNA damage-binding protein 1, ... | | 著者 | Kozicka, Z, Kempf, G, Focht, V, Thoma, N.H. | | 登録日 | 2022-11-30 | | 公開日 | 2023-09-13 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | | 主引用文献 | Design principles for cyclin K molecular glue degraders.
Nat.Chem.Biol., 20, 2024
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8BUB
 | | Structure of DDB1 bound to dCeMM4-engaged CDK12-cyclin K | | 分子名称: | CITRIC ACID, Cyclin-K, Cyclin-dependent kinase 12, ... | | 著者 | Kozicka, Z, Kempf, G, Petzold, G, Thoma, N.H. | | 登録日 | 2022-11-30 | | 公開日 | 2023-09-13 | | 最終更新日 | 2024-01-03 | | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | | 主引用文献 | Design principles for cyclin K molecular glue degraders.
Nat.Chem.Biol., 20, 2024
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8BUP
 | | Structure of DDB1 bound to DS30-engaged CDK12-cyclin K | | 分子名称: | (2~{R})-2-[[6-[3-(3-methylphenyl)propylamino]-9-propan-2-yl-purin-2-yl]amino]butan-1-ol, Cyclin-K, Cyclin-dependent kinase 12, ... | | 著者 | Kozicka, Z, Kempf, G, Petzold, G, Thoma, N.H. | | 登録日 | 2022-11-30 | | 公開日 | 2023-09-13 | | 最終更新日 | 2024-01-03 | | 実験手法 | X-RAY DIFFRACTION (3.41 Å) | | 主引用文献 | Design principles for cyclin K molecular glue degraders.
Nat.Chem.Biol., 20, 2024
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8BUI
 | | Structure of DDB1 bound to DRF-053-engaged CDK12-cyclin K | | 分子名称: | (2~{R})-2-[[9-propan-2-yl-6-[(4-pyridin-2-ylphenyl)amino]purin-2-yl]amino]butan-1-ol, 1,2-ETHANEDIOL, Cyclin-K, ... | | 著者 | Kozicka, Z, Kempf, G, Petzold, G, Thoma, N.H. | | 登録日 | 2022-11-30 | | 公開日 | 2023-09-13 | | 最終更新日 | 2024-01-03 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Design principles for cyclin K molecular glue degraders.
Nat.Chem.Biol., 20, 2024
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8BUE
 | | Structure of DDB1 bound to Z11-engaged CDK12-cyclin K | | 分子名称: | Cyclin-K, Cyclin-dependent kinase 12, DNA damage-binding protein 1, ... | | 著者 | Kozicka, Z, Kempf, G, Petzold, G, Thoma, N.H. | | 登録日 | 2022-11-30 | | 公開日 | 2023-09-13 | | 最終更新日 | 2024-01-03 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Design principles for cyclin K molecular glue degraders.
Nat.Chem.Biol., 20, 2024
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