1P3M
 
 | | Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants | | Descriptor: | Histone H2A, Histone H2B, Histone H3, ... | | Authors: | Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K. | | Deposit date: | 2003-04-17 | | Release date: | 2004-02-24 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions
EMBO J., 23, 2004
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1P3K
 | | Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants | | Descriptor: | Histone H2A, Histone H2B, Histone H3, ... | | Authors: | Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K. | | Deposit date: | 2003-04-17 | | Release date: | 2004-02-24 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions
EMBO J., 23, 2004
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5CPI
 | | Nucleosome containing unmethylated Sat2R DNA | | Descriptor: | DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | Authors: | Osakabe, A, Arimura, Y, Adachi, F, Maehara, K, Ohkawa, Y, Kurumizaka, H. | | Deposit date: | 2015-07-21 | | Release date: | 2015-10-28 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.902 Å) | | Cite: | Influence of DNA methylation on positioning and DNA flexibility of nucleosomes with pericentric satellite DNA.
Open Biology, 5, 2015
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5BO0
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8PP7
 | | human RYBP-PRC1 bound to mononucleosome | | Descriptor: | DNA (215-mer), E3 ubiquitin-protein ligase RING2, Histone H2A, ... | | Authors: | Ciapponi, M, Benda, C, Mueller, J. | | Deposit date: | 2023-07-06 | | Release date: | 2024-03-27 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (2.91 Å) | | Cite: | Structural basis of the histone ubiquitination read-write mechanism of RYBP-PRC1.
Nat.Struct.Mol.Biol., 2024
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7LYA
 | | Cryo-EM structure of the human nucleosome core particle with linked histone proteins H2A and H2B | | Descriptor: | DNA (146-MER), DNA (147-MER), Histone H2A type 1-B/E, ... | | Authors: | Hu, Q, Botuyan, M.V, Zhao, D, Cui, D, Mer, E, Mer, G. | | Deposit date: | 2021-03-06 | | Release date: | 2021-07-28 | | Last modified: | 2021-09-01 | | Method: | ELECTRON MICROSCOPY (2.91 Å) | | Cite: | Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation.
Nature, 596, 2021
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5GT3
 | | Crystal structure of nucleosome particle in the presence of human testis-specific histone variant, hTh2b | | Descriptor: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-D, ... | | Authors: | Kumarevel, T, Sivaraman, P. | | Deposit date: | 2016-08-18 | | Release date: | 2017-02-15 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.91 Å) | | Cite: | Structural analyses of the nucleosome complexes with human testis-specific histone variants, hTh2a and hTh2b
Biophys. Chem., 221, 2017
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3X1V
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5B33
 | | The crystal structure of the H2AZ nucleosome with H3.3. | | Descriptor: | DNA (146-MER), Histone H2A.Z, Histone H2B type 1-J, ... | | Authors: | Horikoshi, N, Taguchi, H, Arimura, Y, Kurumizaka, H. | | Deposit date: | 2016-02-08 | | Release date: | 2016-08-03 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.925 Å) | | Cite: | Crystal structures of heterotypic nucleosomes containing histones H2A.Z and H2A.
Open Biology, 6, 2016
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8G6G
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8EU2
 | | Class3 of the INO80-Hexasome complex | | Descriptor: | DNA (110-MER), Histone H2A type 1, Histone H2B 1.1, ... | | Authors: | Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G. | | Deposit date: | 2022-10-18 | | Release date: | 2023-07-12 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (2.93 Å) | | Cite: | Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility.
Science, 381, 2023
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8KD4
 | | Rpd3S in complex with nucleosome with H3K36MLA modification and 187bp DNA, class1 | | Descriptor: | 187bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ... | | Authors: | Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Zhang, X, Chao, W.C.H, He, J. | | Deposit date: | 2023-08-09 | | Release date: | 2023-09-13 | | Last modified: | 2023-10-11 | | Method: | ELECTRON MICROSCOPY (2.93 Å) | | Cite: | Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex.
Cell Res., 33, 2023
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7K5X
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6PA7
 | | The cryo-EM structure of the human DNMT3A2-DNMT3B3 complex bound to nucleosome. | | Descriptor: | CHLORIDE ION, DNA (167-MER), DNA (cytosine-5)-methyltransferase 3A, ... | | Authors: | Xu, T.H, Liu, M, Zhou, X.E, Liang, G, Zhao, G, Xu, H.E, Melcher, K, Jones, P.A. | | Deposit date: | 2019-06-11 | | Release date: | 2020-06-17 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (2.94 Å) | | Cite: | Structure of nucleosome-bound DNA methyltransferases DNMT3A and DNMT3B.
Nature, 586, 2020
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7LYC
 | | Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A Lys13 and Lys15 in complex with BARD1 (residues 415-777) | | Descriptor: | BRCA1-associated RING domain protein 1, DNA (146-MER), DNA (147-MER), ... | | Authors: | Hu, Q, Botuyan, M.V, Zhao, D, Cui, D, Mer, E, Mer, G. | | Deposit date: | 2021-03-06 | | Release date: | 2021-06-16 | | Last modified: | 2021-09-01 | | Method: | ELECTRON MICROSCOPY (2.94 Å) | | Cite: | Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation.
Nature, 596, 2021
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8OF4
 | | Nucleosome Bound human SIRT6 (Composite) | | Descriptor: | DNA (145-MER), Histone H2A type 1, Histone H2B, ... | | Authors: | Smirnova, E, Bignon, E, Schultz, P, Papai, G, Ben-Shem, A. | | Deposit date: | 2023-03-13 | | Release date: | 2023-08-09 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (2.94 Å) | | Cite: | Binding to nucleosome poises human SIRT6 for histone H3 deacetylation.
Elife, 12, 2024
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3LEL
 | | Structural Insight into the Sequence-Dependence of Nucleosome Positioning | | Descriptor: | 147-MER DNA, Histone H2A, Histone H2B 1.1, ... | | Authors: | Wu, B, Vasudevan, D, Davey, C.A. | | Deposit date: | 2010-01-15 | | Release date: | 2010-05-19 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Structural insight into the sequence dependence of nucleosome positioning
Structure, 18, 2010
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6NJ9
 | | Active state Dot1L bound to the H2B-Ubiquitinated nucleosome, 2-to-1 complex | | Descriptor: | 601 DNA Strand 1, 601 DNA Strand 2, Histone H2A type 1, ... | | Authors: | Worden, E.J, Hoffmann, N.A, Wolberger, C. | | Deposit date: | 2019-01-02 | | Release date: | 2019-02-20 | | Last modified: | 2021-06-16 | | Method: | ELECTRON MICROSCOPY (2.96 Å) | | Cite: | Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.
Cell, 176, 2019
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6X59
 | | The mouse cGAS catalytic domain binding to human assembled nucleosome | | Descriptor: | Cyclic GMP-AMP synthase, DNA, Histone H2A type 1, ... | | Authors: | Pengbiao, X, Pingwei, L, Baoyu, Z. | | Deposit date: | 2020-05-25 | | Release date: | 2020-09-16 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | The molecular basis of tight nuclear tethering and inactivation of cGAS.
Nature, 587, 2020
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4Z2M
 | | Crystal structure of human SPT16 Mid-AID/H3-H4 tetramer FACT Histone complex | | Descriptor: | FACT complex subunit SPT16, Histone H3.1, Histone H4 | | Authors: | Tsunaka, Y, Fujiwara, Y, Oyama, T, Hirose, S, Morikawa, K. | | Deposit date: | 2015-03-30 | | Release date: | 2016-03-09 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.981 Å) | | Cite: | Integrated molecular mechanism directing nucleosome reorganization by human FACT.
Genes Dev., 30, 2016
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6DZT
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3TU4
 | | Crystal structure of the Sir3 BAH domain in complex with a nucleosome core particle. | | Descriptor: | DNA (146-MER), Histone H2A, Histone H2B 1.1, ... | | Authors: | Armache, K.-J, Garlick, J.D, Canzio, D, Narlikar, G.J, Kingston, R.E. | | Deposit date: | 2011-09-15 | | Release date: | 2011-11-23 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis of silencing: Sir3 BAH domain in complex with a nucleosome at 3.0 A resolution.
Science, 334, 2011
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1P3B
 | | Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants | | Descriptor: | Histone H2A, Histone H2B, Histone H3, ... | | Authors: | Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K. | | Deposit date: | 2003-04-17 | | Release date: | 2004-02-24 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions
EMBO J., 23, 2004
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7OH9
 | | Nucleosome with TBP and TFIIA bound at SHL -6 | | Descriptor: | DNA (145-MER), Histone H2A, Histone H2B 1.1, ... | | Authors: | Wang, H, Cramer, P. | | Deposit date: | 2021-05-09 | | Release date: | 2021-07-28 | | Last modified: | 2021-08-04 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structures and implications of TBP-nucleosome complexes.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7V6Q
 | | Crystal structure of sNASP-ASF1A-H3.1-H4 complex | | Descriptor: | GLYCEROL, Histone H3.1, Histone H4, ... | | Authors: | Liu, C.P, Xu, R.M. | | Deposit date: | 2021-08-20 | | Release date: | 2021-12-29 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Distinct histone H3-H4 binding modes of sNASP reveal the basis for cooperation and competition of histone chaperones.
Genes Dev., 35, 2021
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