6JOU
| Crystal structure of the human nucleosome containing H2A.Z.1 S42R | Descriptor: | DNA (146-MER), Histone H2A.Z, Histone H2B type 1-J, ... | Authors: | Horikoshi, N, Sato, K, Mizukami, Y, Kurumizaka, H. | Deposit date: | 2019-03-23 | Release date: | 2020-03-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Structure-based design of an H2A.Z.1 mutant stabilizing a nucleosome in vitro and in vivo. Biochem.Biophys.Res.Commun., 515, 2019
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5Z30
| The crystal structure of the nucleosome containing a cancer-associated histone H2A.Z R80C mutant | Descriptor: | CHLORIDE ION, DNA (146-MER), Histone H2A.Z, ... | Authors: | Horikoshi, N, Arimura, Y, Kurumizaka, H. | Deposit date: | 2018-01-05 | Release date: | 2018-07-18 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome. Nucleic Acids Res., 46, 2018
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6VA8
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6VA7
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6VA9
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6VAQ
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6VA0
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3WAA
| The nucleosome containing human H2A.Z.2 | Descriptor: | DNA (146-MER), Histone H2A.V, Histone H2B type 1-J, ... | Authors: | Horikoshi, N, Sato, K, Shimada, K, Arimura, Y, Osakabe, A, Tachiwana, H, Iwasaki, W, Kagawa, W, Harata, M, Kimura, H, Kurumizaka, H. | Deposit date: | 2013-04-30 | Release date: | 2013-12-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural polymorphism in the L1 loop regions of human H2A.Z.1 and H2A.Z.2 Acta Crystallogr.,Sect.D, 69, 2013
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3WA9
| The nucleosome containing human H2A.Z.1 | Descriptor: | DNA (146-MER), Histone H2A.Z, Histone H2B type 1-J, ... | Authors: | Horikoshi, N, Sato, K, Shimada, K, Arimura, Y, Osakabe, A, Tachiwana, H, Iwasaki, W, Kagawa, W, Harata, M, Kimura, H, Kurumizaka, H. | Deposit date: | 2013-04-30 | Release date: | 2013-12-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.07 Å) | Cite: | Structural polymorphism in the L1 loop regions of human H2A.Z.1 and H2A.Z.2 Acta Crystallogr.,Sect.D, 69, 2013
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5B32
| The crystal structure of the heterotypic H2AZ/H2A nucleosome with H3.3. | Descriptor: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... | Authors: | Horikoshi, N, Taguchi, H, Arimura, Y, Kurumizaka, H. | Deposit date: | 2016-02-08 | Release date: | 2016-08-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal structures of heterotypic nucleosomes containing histones H2A.Z and H2A. Open Biology, 6, 2016
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5B24
| The crystal structure of the nucleosome containing cyclobutane pyrimidine dimer | Descriptor: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Horikoshi, N, Tachiwana, H, Kagawa, W, Osakabe, A, Kurumizaka, H. | Deposit date: | 2015-12-31 | Release date: | 2016-03-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Crystal structure of the nucleosome containing ultraviolet light-induced cyclobutane pyrimidine dimer Biochem.Biophys.Res.Commun., 471, 2016
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5B31
| The crystal structure of the heterotypic H2AZ/H2A nucleosome with H3.1. | Descriptor: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... | Authors: | Horikoshi, N, Taguchi, H, Arimura, Y, Kurumizaka, H. | Deposit date: | 2016-02-08 | Release date: | 2016-08-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of heterotypic nucleosomes containing histones H2A.Z and H2A. Open Biology, 6, 2016
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5B33
| The crystal structure of the H2AZ nucleosome with H3.3. | Descriptor: | DNA (146-MER), Histone H2A.Z, Histone H2B type 1-J, ... | Authors: | Horikoshi, N, Taguchi, H, Arimura, Y, Kurumizaka, H. | Deposit date: | 2016-02-08 | Release date: | 2016-08-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.925 Å) | Cite: | Crystal structures of heterotypic nucleosomes containing histones H2A.Z and H2A. Open Biology, 6, 2016
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3APM
| Crystal structure of the human SNP PAD4 protein | Descriptor: | Protein-arginine deiminase type-4 | Authors: | Horikoshi, N, Tachiwana, H, Saito, K, Osakabe, A, Sato, M, Yamada, M, Akashi, S, Nishimura, Y, Kagawa, W, Kurumizaka, H. | Deposit date: | 2010-10-19 | Release date: | 2011-01-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and biochemical analyses of the human PAD4 variant encoded by a functional haplotype gene Acta Crystallogr.,Sect.D, 67, 2011
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3APN
| Crystal structure of the human wild-type PAD4 protein | Descriptor: | Protein-arginine deiminase type-4 | Authors: | Horikoshi, N, Tachiwana, H, Saito, K, Osakabe, A, Sato, M, Yamada, M, Akashi, S, Nishimura, Y, Kagawa, W, Kurumizaka, H. | Deposit date: | 2010-10-19 | Release date: | 2011-01-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and biochemical analyses of the human PAD4 variant encoded by a functional haplotype gene Acta Crystallogr.,Sect.D, 67, 2011
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5JRG
| Crystal structure of the nucleosome containing the DNA with tetrahydrofuran (THF) | Descriptor: | CHLORIDE ION, DNA (145-MER), Histone H2A type 1-B/E, ... | Authors: | Osakabe, A, Arimura, Y, Horikoshi, N, Kurumizaka, H. | Deposit date: | 2016-05-06 | Release date: | 2017-03-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Polymorphism of apyrimidinic DNA structures in the nucleosome Sci Rep, 7, 2017
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5XM0
| The mouse nucleosome structure containing H2A, H2B type3-A, H3.3, and H4 | Descriptor: | DNA (146-MER), Histone H2A type 1-B, Histone H2B type 3-A, ... | Authors: | Taguchi, H, Horikoshi, N, Kurumizaka, H. | Deposit date: | 2017-05-12 | Release date: | 2018-03-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.874 Å) | Cite: | Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration. Nat Commun, 9, 2018
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3W99
| Crystal Structure of Human Nucleosome Core Particle lacking H4 N-terminal region | Descriptor: | 146-mer DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Iwasaki, W, Miya, Y, Horikoshi, N, Osakabe, A, Tachiwana, H, Shibata, T, Kagawa, W, Kurumizaka, H. | Deposit date: | 2013-04-01 | Release date: | 2013-08-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Contribution of histone N-terminal tails to the structure and stability of nucleosomes FEBS Open Bio, 3, 2013
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3W98
| Crystal Structure of Human Nucleosome Core Particle lacking H3.1 N-terminal region | Descriptor: | 146-mer DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Iwasaki, W, Miya, Y, Horikoshi, N, Osakabe, A, Tachiwana, H, Shibata, T, Kagawa, W, Kurumizaka, H. | Deposit date: | 2013-04-01 | Release date: | 2013-08-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.42 Å) | Cite: | Contribution of histone N-terminal tails to the structure and stability of nucleosomes FEBS Open Bio, 3, 2013
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7TBH
| cryo-EM structure of MBP-KIX-apoferritin complex with peptide 7 | Descriptor: | Isoform 2 of CREB-binding protein,Ferritin heavy chain, N-terminally processed, LEU-SER-ARG-ARG-PRO-SEP-TYR-ARG-LYS-ILE-LEU-ASN-ASP-LEU-SER-SER-ASP-ALA-PRO | Authors: | Zhang, K, Horikoshi, N, Li, S, Powers, A, Hameedi, M, Pintilie, G, Chae, H, Khan, Y, Suomivuori, C, Dror, R, Sakamoto, K, Chiu, W, Wakatsuki, S. | Deposit date: | 2021-12-22 | Release date: | 2022-03-16 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Cryo-EM, Protein Engineering, and Simulation Enable the Development of Peptide Therapeutics against Acute Myeloid Leukemia. Acs Cent.Sci., 8, 2022
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8J92
| Cryo-EM structure of nucleosome containing Arabidopsis thaliana H2A.W | Descriptor: | DNA (169-MER), HTA6, HTB9, ... | Authors: | Osakabe, A, Takizawa, Y, Horikoshi, N, Hatazawa, S, Berger, F, Kurumizaka, H, Kakutani, T. | Deposit date: | 2023-05-02 | Release date: | 2024-07-03 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Molecular and structural basis of the chromatin remodeling activity by Arabidopsis DDM1. Nat Commun, 15, 2024
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8J91
| Cryo-EM structure of nucleosome containing Arabidopsis thaliana histones | Descriptor: | DNA (169-MER), HTA13, Histone H2B.6, ... | Authors: | Osakabe, A, Takizawa, Y, Horikoshi, N, Hatazawa, S, Berger, F, Kurumizaka, H, Kakutani, T. | Deposit date: | 2023-05-02 | Release date: | 2024-07-03 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Molecular and structural basis of the chromatin remodeling activity by Arabidopsis DDM1. Nat Commun, 15, 2024
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8J90
| Cryo-EM structure of DDM1-nucleosome complex | Descriptor: | ATP-dependent DNA helicase DDM1, DNA (169-MER), HTA6, ... | Authors: | Osakabe, A, Takizawa, Y, Horikoshi, N, Hatazawa, S, Berger, F, Kurumizaka, H, Kakutani, T. | Deposit date: | 2023-05-02 | Release date: | 2024-07-03 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (4.71 Å) | Cite: | Molecular and structural basis of the chromatin remodeling activity by Arabidopsis DDM1. Nat Commun, 15, 2024
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7TB3
| cryo-EM structure of MBP-KIX-apoferritin | Descriptor: | Isoform 2 of CREB-binding protein,Ferritin heavy chain, N-terminally processed | Authors: | Zhang, K, Horikoshi, N, Li, S, Powers, A, Hameedi, M, Pintilie, G, Chae, H, Khan, Y, Suomivuori, C, Dror, R, Sakamoto, K, Chiu, W, Wakatsuki, S. | Deposit date: | 2021-12-21 | Release date: | 2022-03-16 | Method: | ELECTRON MICROSCOPY (2.57 Å) | Cite: | Cryo-EM, Protein Engineering, and Simulation Enable the Development of Peptide Therapeutics against Acute Myeloid Leukemia. Acs Cent.Sci., 8, 2022
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5GXQ
| The crystal structure of the nucleosome containing H3.6 | Descriptor: | DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Taguchi, H, Xie, Y, Horikoshi, N, Kurumizaka, H. | Deposit date: | 2016-09-19 | Release date: | 2017-04-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystal Structure and Characterization of Novel Human Histone H3 Variants, H3.6, H3.7, and H3.8 Biochemistry, 56, 2017
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