1GZ6
 
 | | (3R)-HYDROXYACYL-COA DEHYDROGENASE FRAGMENT OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2 | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ESTRADIOL 17 BETA-DEHYDROGENASE 4, SULFATE ION | | 著者 | Haapalainen, A.M, Hiltunen, J.K, Glumoff, T. | | 登録日 | 2002-05-16 | | 公開日 | 2003-01-24 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Binary Structure of the Two-Domain (3R)-Hydroxyacyl-Coa Dehydrogenase from Rat Peroxisomal Multifunctional Enzyme Type 2 at 2.38 A Resolution
Structure, 11, 2003
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1HDC
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3L77
 | | X-ray structure alcohol dehydrogenase from archaeon Thermococcus sibiricus complexed with 5-hydroxy-NADP | | 分子名称: | 1,2-ETHANEDIOL, 5-hydroxy-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GLYCEROL, ... | | 著者 | Lyashenko, A.V, Lashkov, A.A, Gabdoulkhakov, A.G, Mikhailov, A.M. | | 登録日 | 2009-12-28 | | 公開日 | 2011-01-19 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | X-ray structure alcohol dehydrogenase from archaeon Thermococcus sibiricus complexed with 5-hydroxy-NADP
To be Published
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3LF1
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3L6E
 | | Crystal structure of putative short chain dehydrogenase/reductase family oxidoreductase from Aeromonas hydrophila subsp. hydrophila ATCC 7966 | | 分子名称: | Oxidoreductase, short-chain dehydrogenase/reductase family, SULFATE ION | | 著者 | Malashkevich, V.N, Patskovsky, Y, Toro, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2009-12-23 | | 公開日 | 2010-02-09 | | 最終更新日 | 2021-02-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of putative short chain dehydrogenase/reductase family oxidoreductase from Aeromonas
hydrophila subsp. hydrophila ATCC 7966
To be Published
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3LF2
 | | NADPH Bound Structure of the Short Chain Oxidoreductase Q9HYA2 from Pseudomonas aeruginosa PAO1 Containing an Atypical Catalytic Center | | 分子名称: | CHLORIDE ION, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Huether, R, Umland, T.C, Duax, W.L. | | 登録日 | 2010-01-15 | | 公開日 | 2010-04-14 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The short-chain oxidoreductase Q9HYA2 from Pseudomonas aeruginosa PAO1 contains an atypical catalytic center.
Protein Sci., 19, 2010
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3LZ6
 | | Guinea Pig 11beta hydroxysteroid dehydrogenase with PF-877423 | | 分子名称: | Corticosteroid 11-beta-dehydrogenase isozyme 1, N-adamantan-2-yl-1-ethyl-D-prolinamide, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Pauly, T.A. | | 登録日 | 2010-03-01 | | 公開日 | 2011-05-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | The development and SAR of pyrrolidine carboxamide 11beta-HSD1 inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
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3M1A
 | | The Crystal Structure of a Short-chain Dehydrogenase from Streptomyces avermitilis to 2A | | 分子名称: | ACETATE ION, Putative dehydrogenase, SODIUM ION | | 著者 | Stein, A.J, Evdokimova, E, Egorova, O, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2010-03-04 | | 公開日 | 2010-03-23 | | 最終更新日 | 2021-10-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Crystal Structure of a Short-chain Dehydrogenase from Streptomyces avermitilis to 2A
To be Published
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3NYW
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3OEC
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3ORF
 | | Crystal Structure of Dihydropteridine Reductase from Dictyostelium discoideum | | 分子名称: | Dihydropteridine reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Chen, C, Zhuang, N.N, Seo, K.H, Park, Y.S, Lee, K.H. | | 登録日 | 2010-09-07 | | 公開日 | 2011-07-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Structural insights into the dual substrate specificities of mammalian and Dictyostelium dihydropteridine reductases toward two stereoisomers of quinonoid dihydrobiopterin
Febs Lett., 585, 2011
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3OQ1
 | | Crystal Structure of 11beta-Hydroxysteroid Dehydrogenase-1 (11b-HSD1) in Complex with Diarylsulfone Inhibitor | | 分子名称: | 3-(2-fluoroethyl)-4-({4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]phenyl}sulfonyl)benzonitrile, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Wang, Z, Sudom, A, Walker, N.P. | | 登録日 | 2010-09-02 | | 公開日 | 2011-07-20 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The synthesis and SAR of novel diarylsulfone 11beta-HSD1 inhibitors
Bioorg.Med.Chem.Lett., 20, 2010
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3P19
 | | Improved NADPH-dependent Blue Fluorescent Protein | | 分子名称: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative blue fluorescent protein | | 著者 | Kao, T.H, Chen, Y, Pai, C.H, Wang, A.H.J. | | 登録日 | 2010-09-30 | | 公開日 | 2011-07-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure of a NADPH-dependent blue fluorescent protein revealed the unique role of Gly176 on the fluorescence enhancement.
J.Struct.Biol., 174, 2011
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3PDJ
 | | Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase 1 (11b-HSD1) in Complex with 4,4-Disubstituted Cyclohexylbenzamide Inhibitor | | 分子名称: | Corticosteroid 11-beta-dehydrogenase isozyme 1, N-[trans-4-(3-amino-3-oxopropyl)-4-phenylcyclohexyl]-N-cyclopropyl-4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]benzamide, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Wang, Z, Sudom, A, Walker, N.P. | | 登録日 | 2010-10-22 | | 公開日 | 2011-10-05 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Synthesis and Optimization of Novel 4,4-Disubstituted Cyclohexylbenzamide Derivatives as Potent 11beta-HSD1 Inhibitors
Bioorg.Med.Chem.Lett., 21, 2011
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3QLJ
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3QRW
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3QQP
 | | Crystal Structure of 11beta-Hydroxysteroid Dehydrogenase 1 (11b-HSD1) in Complex with Urea Inhibitor | | 分子名称: | 3,4-dihydroquinolin-1(2H)-yl[4-(1H-imidazol-5-yl)piperidin-1-yl]methanone, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Loenze, P, Schimanski-Breves, S, Engel, C.K. | | 登録日 | 2011-02-16 | | 公開日 | 2012-02-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | | 主引用文献 | Pyrrolidine-pyrazole ureas as potent and selective inhibitors of 11beta-hydroxysteroid-dehydrogenase type 1.
Bioorg.Med.Chem.Lett., 21, 2011
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3RKU
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3RJ5
 | | Structure of alcohol dehydrogenase from Drosophila lebanonesis T114V mutant complexed with NAD+ | | 分子名称: | ACETIC ACID, Alcohol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Morgunova, E, Wuxiuer, Y, Cols, N, Popov, A, Sylte, I, Karshikoff, A, Gonzales-Duarte, R, Ladenstein, R, Winberg, J.O. | | 登録日 | 2011-04-15 | | 公開日 | 2012-05-02 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | An intact eight-membered water chain in drosophilid alcohol dehydrogenases is essential for optimal enzyme activity.
Febs J., 279, 2012
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3RI3
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3RJ9
 | | Structure of alcohol dehydrogenase from Drosophila lebanonesis T114V mutant complexed with NAD+ | | 分子名称: | Alcohol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Morgunova, E, Wuxiuer, Y, Cols, N, Popov, A, Sylte, I, Karshikoff, A, Gonzales-Duarte, R, Ladenstein, R, Winberg, J.O. | | 登録日 | 2011-04-15 | | 公開日 | 2012-05-02 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | An intact eight-membered water chain in drosophilid alcohol dehydrogenases is essential for optimal enzyme activity.
Febs J., 279, 2012
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3RKR
 | | Crystal structure of a metagenomic short-chain oxidoreductase (SDR) in complex with NADP | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, Short chain oxidoreductase | | 著者 | Mayerhofer, H, Bijtenhoorn, P, Streit, W.R, Mueller-Dieckmann, J. | | 登録日 | 2011-04-18 | | 公開日 | 2011-11-30 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | A novel metagenomic short-chain dehydrogenase/reductase attenuates Pseudomonas aeruginosa biofilm formation and virulence on Caenorhabditis elegans.
Plos One, 6, 2011
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3RD5
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3S55
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3SC4
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