1PSJ
| ACIDIC PHOSPHOLIPASE A2 FROM AGKISTRODON HALYS PALLAS | Descriptor: | CALCIUM ION, PHOSPHOLIPASE A2 | Authors: | Wang, X.Q, Lin, Z.J. | Deposit date: | 1995-05-24 | Release date: | 1996-07-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of an acidic phospholipase A2 from the venom of Agkistrodon halys pallas at 2.0 A resolution. J.Mol.Biol., 255, 1996
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1PO8
| Crystal structure of a complex formed between krait venom phospholipase A2 and heptanoic acid at 2.7 A resolution. | Descriptor: | HEPTANOIC ACID, Phospholipase A2, SODIUM ION | Authors: | Singh, G, Jayasankar, J, Sharma, S, Kaur, P, Singh, T.P. | Deposit date: | 2003-06-14 | Release date: | 2004-05-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Crystal structure of a complex formed between krait venom phospholipase A2 and heptanoic acid at 2.7 A resolution. To be Published
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1POD
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1POA
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1PPA
| THE CRYSTAL STRUCTURE OF A LYSINE 49 PHOSPHOLIPASE A2 FROM THE VENOM OF THE COTTONMOUTH SNAKE AT 2.0 ANGSTROMS RESOLUTION | Descriptor: | ANILINE, PHOSPHOLIPASE A2 | Authors: | Holland, D.R, Clancy, L.L, Muchmore, S.W, Rydel, T.J, Einspahr, H.M, Finzel, B.C, Heinrikson, R.L, Watenpaugh, K.D. | Deposit date: | 1991-10-29 | Release date: | 1994-01-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structure of a lysine 49 phospholipase A2 from the venom of the cottonmouth snake at 2.0-A resolution. J.Biol.Chem., 265, 1990
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1PIS
| SOLUTION STRUCTURE OF PORCINE PANCREATIC PHOSPHOLIPASE A2 | Descriptor: | CALCIUM ION, PHOSPHOLIPASE A2 | Authors: | Van Den Berg, B.D, Tessari, M, De Haas, G.H, Verheij, H.M, Boelens, R, Kaptein, R. | Deposit date: | 1994-12-22 | Release date: | 1995-06-03 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structure of porcine pancreatic phospholipase A2. EMBO J., 14, 1995
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1Q7A
| Crystal structure of the complex formed between russell's viper phospholipase A2 and an antiinflammatory agent oxyphenbutazone at 1.6A resolution | Descriptor: | 4-BUTYL-1-(4-HYDROXYPHENYL)-2-PHENYLPYRAZOLIDINE-3,5-DIONE, METHANOL, Phospholipase A2 VRV-PL-VIIIa, ... | Authors: | Singh, N, Jabeen, T, Sharma, S, Singh, T.P. | Deposit date: | 2003-08-17 | Release date: | 2004-05-11 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Phospholipase A2 as a target protein for nonsteroidal anti-inflammatory drugs (NSAIDS): crystal structure of the complex formed between phospholipase A2 and oxyphenbutazone at 1.6 A resolution. Biochemistry, 43, 2004
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1Q6V
| First crystal structure of a C49 monomer PLA2 from the venom of Daboia russelli pulchella at 1.8 A resolution | Descriptor: | Phospholipase A2 VRV-PL-VIIIa, SULFATE ION | Authors: | Singh, N, Pal, A, Jabeen, T, Sharma, S, Singh, T.P. | Deposit date: | 2003-08-14 | Release date: | 2004-05-04 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | First crystal structure of a C49 PLA2 from the venom of Daboia russelli pulchella at 1.8A resolution To be Published
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1QLL
| Piratoxin-II (Prtx-II) - a K49 PLA2 from Bothrops pirajai | Descriptor: | N-TRIDECANOIC ACID, PHOSPHOLIPASE A2 | Authors: | Lee, W.-H, Polikarpov, I. | Deposit date: | 1999-09-01 | Release date: | 2000-09-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Structural Basis for Low Catalytic Activity in Lys49 Phospholipases A2-A Hypothesis: The Crystal Structure of Piratoxin II Complexed to Fatty Acid Biochemistry, 40, 2001
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1RGB
| Phospholipase A2 from Vipera ammodytes meridionalis | Descriptor: | (9E)-OCTADEC-9-ENAMIDE, Phospholipase A2 | Authors: | Georgieva, D.N. | Deposit date: | 2003-11-12 | Release date: | 2005-01-18 | Last modified: | 2018-10-03 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Asp49 phospholipase A(2)-elaidoylamide complex: a new mode of inhibition. Biochem.Biophys.Res.Commun., 319, 2004
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1S8G
| Crystal structure of Lys49-Phospholipase A2 from Agkistrodon contortrix laticinctus, fatty acid bound form | Descriptor: | GLYCEROL, LAURIC ACID, Phospholipase A2 homolog, ... | Authors: | Ambrosio, A.L.B, de Souza, D.H.F, Nonato, M.C, Selistre de Araujo, H.S, Ownby, C.L, Garratt, R.C. | Deposit date: | 2004-02-02 | Release date: | 2004-02-10 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A Molecular Mechanism for Lys49-Phospholipase A2 Activity Based on Ligand-induced Conformational Change. J.Biol.Chem., 280, 2005
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1SKG
| Structure-based rational drug design: Crystal structure of the complex formed between Phospholipase A2 and a pentapeptide Val-Ala-Phe-Arg-Ser | Descriptor: | METHANOL, Phospholipase A2, SULFATE ION, ... | Authors: | Ethayathulla, A.S, Singh, N, Sharma, S, Makker, J, Dey, S, Perbandt, M, Betzel, C, Singh, T.P. | Deposit date: | 2004-03-04 | Release date: | 2004-04-27 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.21 Å) | Cite: | Structure-based rational drug design: Crystal structure of the complex formed between Phospholipase A2 and a pentapeptide Val-Ala-Phe-Arg-Ser To be Published
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1SFW
| PORCINE PANCREAS PHOSPHOLIPASE A2, NMR, 18 STRUCTURES | Descriptor: | CALCIUM ION, PHOSPHOLIPASE A2 | Authors: | Van Den Berg, B, Tessari, M, Boelens, R, Dijkman, R, Kaptein, R, De Haas, G.H, Verheij, H.M. | Deposit date: | 1996-02-23 | Release date: | 1996-07-11 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Solution structure of porcine pancreatic phospholipase A2 complexed with micelles and a competitive inhibitor. J.Biomol.NMR, 5, 1995
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1S6B
| X-ray Crystal Structure of a Complex Formed Between Two Homologous Isoforms of Phospholipase A2 from Naja naja sagittifera: Principle of Molecular Association and Inactivation | Descriptor: | ACETIC ACID, CALCIUM ION, PHOSPHATE ION, ... | Authors: | Jabeen, T, Sharma, S, Singh, R.K, Kaur, P, Singh, T.P. | Deposit date: | 2004-01-23 | Release date: | 2004-02-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of a calcium-induced dimer of two isoforms of cobra phospholipase A2 at 1.6 A resolution. Proteins, 59, 2005
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1S8I
| Crystal structure of Lys49-Phospholipase A2 from Agkistrodon contortrix laticinctus, second fatty acid free form | Descriptor: | Phospholipase A2 homolog, SULFATE ION | Authors: | Ambrosio, A.L.B, de Souza, D.H.F, Nonato, M.C, Selistre de Araujo, H.S, Ownby, C.L, Garratt, R.C. | Deposit date: | 2004-02-02 | Release date: | 2004-02-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.609 Å) | Cite: | A Molecular Mechanism for Lys49-Phospholipase A2 Activity Based on Ligand-induced Conformational Change. J.Biol.Chem., 280, 2005
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1S8H
| Crystal structure of Lys49-Phospholipase A2 from Agkistrodon contortrix laticinctus, first fatty acid free form | Descriptor: | Phospholipase A2 homolog, SULFATE ION | Authors: | Ambrosio, A.L.B, de Souza, D.H.F, Nonato, M.C, Selistre de Araujo, H.S, Ownby, C.L, Garratt, R.C. | Deposit date: | 2004-02-02 | Release date: | 2004-02-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A Molecular Mechanism for Lys49-Phospholipase A2 Activity Based on Ligand-induced Conformational Change. J.Biol.Chem., 280, 2005
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1SQZ
| Design of specific inhibitors of Phopholipase A2: Crystal structure of the complex formed between Group II Phopholipase A2 and a designed peptide Dehydro-Ile-Ala-Arg-Ser at 1.2A resolution | Descriptor: | Phospholipase A2, SULFATE ION, synthetic peptide | Authors: | Singh, N, Prem Kumar, R, Somvanshi, R.K, Bilgrami, S, Ethayathulla, A.S, Sharma, S, Dey, S, Singh, T.P. | Deposit date: | 2004-03-22 | Release date: | 2004-04-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Design of specific inhibitors of Phopholipase A2: Crystal structure of the complex formed between GroupII Phopholipase A2 and a designed peptide Dehydro-Ile-Ala-Arg-Ser at 1.2A resolution To be Published
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1SFV
| PORCINE PANCREAS PHOSPHOLIPASE A2, NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | CALCIUM ION, PHOSPHOLIPASE A2 | Authors: | Van Den Berg, B, Tessari, M, Boelens, R, Dijkman, R, Kaptein, R, De Haas, G.H, Verheij, H.M. | Deposit date: | 1996-02-20 | Release date: | 1996-07-11 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Solution structure of porcine pancreatic phospholipase A2 complexed with micelles and a competitive inhibitor. J.Biomol.NMR, 5, 1995
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1SV9
| Crystal structure of the complex formed between groupII phospholipase A2 and anti-inflammatory agent 2-[(2,6-Dichlorophenyl)amino] benzeneacetic acid at 2.7A resolution | Descriptor: | 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, Phospholipase A2 | Authors: | Senthil kumar, R, Singh, N, Ethayathulla, A.S, Prem kumar, R, Sharma, S, Singh, T.P. | Deposit date: | 2004-03-29 | Release date: | 2004-04-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Crystal structure of the complex formed between group II phospholipase A2 and anti-inflammatory agent 2-[(2,6-Dichlorophenyl)amino] benzeneacetic acid at 2.7A resolution To be Published
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1TDV
| Non-specific binding to phospholipase A2:Crystal structure of the complex of PLA2 with a designed peptide Tyr-Trp-Ala-Ala-Ala-Ala at 1.7A resolution | Descriptor: | Phospholipase A2 VRV-PL-VIIIa, SULFATE ION, YWAAAA | Authors: | Singh, N, Jabeen, T, Ethayathulla, A.S, Somvanshi, R.K, Sharma, S, Dey, S, Perbandt, M, Betzel, C, Singh, T.P. | Deposit date: | 2004-05-24 | Release date: | 2004-06-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Non-specific binding to phospholipase A2:Crystal structure of the complex of PLA2 with a designed peptide Tyr-Trp-Ala-Ala-Ala-Ala at 1.7A resolution to be published
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1TG1
| Crystal Structure of the complex formed between russells viper phospholipase A2 and a designed peptide inhibitor PHQ-Leu-Val-Arg-Tyr at 1.2A resolution | Descriptor: | ACETIC ACID, METHANOL, Phospholipase A2, ... | Authors: | Singh, N, Kaur, P, Somvanshi, R.K, Sharma, S, Dey, S, Perbandt, M, Betzel, C, Singh, T.P. | Deposit date: | 2004-05-28 | Release date: | 2004-06-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Crystal Structure of the complex formed between russells viper phospholipase A2 and a designed peptide inhibitor Cbz-dehydro-Leu-Val-Arg-Tyr at 1.2A resolution To be Published
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1TD7
| Interactions of a specific non-steroidal anti-inflammatory drug (NSAID) with group I phospholipase A2 (PLA2): Crystal structure of the complex formed between PLA2 and niflumic acid at 2.5 A resolution | Descriptor: | 2-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}NICOTINIC ACID, CALCIUM ION, Phospholipase A2 isoform 3 | Authors: | Jabeen, T, Singh, N, Singh, R.K, Sharma, S, Perbandt, M, Betzel, C, Singh, T.P. | Deposit date: | 2004-05-21 | Release date: | 2004-06-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Non-steroidal anti-inflammatory drugs as potent inhibitors of phospholipase A2: structure of the complex of phospholipase A2 with niflumic acid at 2.5 Angstroms resolution. Acta Crystallogr.,Sect.D, 61, 2005
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1TGM
| Crystal structure of a complex formed between group II phospholipase A2 and aspirin at 1.86 A resolution | Descriptor: | 2-(ACETYLOXY)BENZOIC ACID, CALCIUM ION, Phospholipase A2, ... | Authors: | Singh, N, Jabeen, T, Sharma, S, Bhushan, A, Singh, T.P. | Deposit date: | 2004-05-28 | Release date: | 2004-06-08 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Crystal structure of a complex formed between group II phospholipase A2 and aspirin at 1.86 A resolution To be Published
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1TJK
| Crystal structure of the complex formed between group II phospholipase A2 with a designed pentapeptide, Phe- Leu- Ser- Thr- Lys at 1.2 A resolution | Descriptor: | Phospholipase A2, SULFATE ION, synthetic peptide | Authors: | Singh, N, Jabeen, T, Somvanshi, R.K, Sharma, S, Perbandt, M, Dey, S, Betzel, C, Singh, T.P. | Deposit date: | 2004-06-06 | Release date: | 2004-06-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Crystal structure of the complex formed between group II phospholipase A2 with a designed pentapeptide, Phe - Leu - Ser - Thr - Lys at 1.2 A resolution To be Published
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1SV3
| Structure of the complex formed between Phospholipase A2 and 4-methoxybenzoic acid at 1.3A resolution. | Descriptor: | 4-METHOXYBENZOIC ACID, Phospholipase A2, SULFATE ION | Authors: | Singh, N, Prahathees, E, Jabeen, T, Pal, A, Ethayathulla, A.S, Prem kumar, R, Sharma, S, Singh, T.P. | Deposit date: | 2004-03-27 | Release date: | 2004-04-13 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Crystal structures of the complexes of a group IIA phospholipase A2 with two natural anti-inflammatory agents, anisic acid, and atropine reveal a similar mode of binding Proteins, 64, 2006
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