1S6B

X-ray Crystal Structure of a Complex Formed Between Two Homologous Isoforms of Phospholipase A2 from Naja naja sagittifera: Principle of Molecular Association and Inactivation

Replaces:  1LFJ

Summary for 1S6B

• Entry DOI: 10.2210/pdb1s6b/pdb
• Descriptor: Phospholipase A2 isoform 1, Phospholipase A2 isoform 2, CALCIUM ION, ... (6 entities in total)
• Functional Keywords: phospholipase a2, molecular conformation, enzyme activity, hydrolase
• Biological source: Naja sagittifera; More
• Cellular location: Secreted: P60043 P60044
• Total number of polymer chains: 2
• Total formula weight: 26899.57

Authors

Jabeen, T.,Sharma, S.,Singh, R.K.,Kaur, P.,Singh, T.P. (deposition date: 2004-01-23, release date: 2004-02-10, Last modification date: 2023-10-25)

• Primary citation: Jabeen, T.,Sharma, S.,Singh, N.,Singh, R.K.,Kaur, P.,Perbandt, M.,Betzel, C.h.,Srinivasan, A.,Singh, T.P.; Crystal structure of a calcium-induced dimer of two isoforms of cobra phospholipase A2 at 1.6 A resolution.; Proteins, 59:856-863, 2005; PubMed: 15828003; DOI: 10.1002/prot.20464

Experimental method

X-RAY DIFFRACTION (1.6 Å)