PDB: 34 resultsInfo pagesStatus searchChemie searchBIRD

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1N7D	Extracellular domain of the LDL receptor Descriptor: 12-TUNGSTOPHOSPHATE, CALCIUM ION, Low-density lipoprotein receptor, ... Authors: Rudenko, G, Henry, L, Henderson, K, Ichtchenko, K, Brown, M.S, Goldstein, J.L, Deisenhofer, J. Deposit date: 2002-11-13 Release date: 2003-01-21 Last modified: 2021-10-27 Method: X-RAY DIFFRACTION (3.7 Å) Cite: Structure of the LDL receptor extracellular domain at endosomal pH Science, 298, 2002
8CTG	Extracellular architecture of an engineered canonical Wnt signaling ternary complex Descriptor: Frizzled-8, Low-density lipoprotein receptor-related protein 6, PALMITOLEIC ACID, ... Authors: Tsutsumi, N, Jude, K.M, Garcia, K.C. Deposit date: 2022-05-14 Release date: 2023-03-15 Last modified: 2023-03-22 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structure of the Wnt-Frizzled-LRP6 initiation complex reveals the basis for coreceptor discrimination. Proc.Natl.Acad.Sci.USA, 120, 2023
6L6R	Crystal structure of LRP6 E1E2-SOST complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... Authors: Choi, H.-J, Kim, J. Deposit date: 2019-10-29 Release date: 2020-10-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.8 Å) Cite: Sclerostin inhibits Wnt signaling through tandem interaction with two LRP6 ectodomains. Nat Commun, 11, 2020
8S9P	1:1:1 agrin/LRP4/MuSK complex Descriptor: Agrin, Low-density lipoprotein receptor-related protein 4, Muscle, ... Authors: Xie, T, Xu, G.J, Liu, Y, Quade, B, Lin, W.C, Bai, X.C. Deposit date: 2023-03-29 Release date: 2023-05-17 Last modified: 2023-06-14 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structural insights into the assembly of the agrin/LRP4/MuSK signaling complex. Proc.Natl.Acad.Sci.USA, 120, 2023
8UFB	Eastern equine encephalitis virus (PE-6) VLP in complex with full-length VLDLR (asymmetric unit) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Capsid protein, ... Authors: Adams, L.J, Fremont, D.H, Center for Structural Biology of Infectious Diseases (CSBID) Deposit date: 2023-10-04 Release date: 2024-01-17 Last modified: 2024-01-31 Method: ELECTRON MICROSCOPY (3.89 Å) Cite: Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus. Cell, 187, 2024
3P5C	The structure of the LDLR/PCSK9 complex reveals the receptor in an extended conformation Descriptor: CALCIUM ION, Low density lipoprotein receptor variant, Proprotein convertase subtilisin/kexin type 9 Authors: Lo Surdo, P, Bottomley, M.J, Calzetta, A, Settembre, E.C, Cirillo, A, Pandit, S, Ni, Y, Hubbard, B, Sitlani, A, Carfi, A. Deposit date: 2010-10-08 Release date: 2011-10-26 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (4.2 Å) Cite: Mechanistic implications for LDL receptor degradation from the PCSK9/LDLR structure at neutral pH. Embo Rep., 12, 2011
8S7C	Ternary Complex of Cachd1, FZD5 and LRP6 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-5, ... Authors: Zhao, Y, Ren, J, Jones, E.Y. Deposit date: 2024-02-29 Release date: 2024-04-24 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (4.7 Å) Cite: Cachd1 interacts with Wnt receptors and regulates neuronal asymmetry in the zebrafish brain. Science, 384, 2024
3M0C	The X-ray Crystal Structure of PCSK9 in Complex with the LDL receptor Descriptor: CALCIUM ION, Low-density lipoprotein receptor, Proprotein convertase subtilisin/kexin type 9 Authors: Spraggon, G, Hampton, E.N. Deposit date: 2010-03-02 Release date: 2011-03-16 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (7.01 Å) Cite: The X-ray Crystal Structure of PCSK9 in Complex with the LDL receptor To be Published
5GJE	Three-dimensional reconstruction of human LRP6 ectodomain complexed with Dkk1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Matoba, K, Mihara, E, Tamura-Kawakami, K, Hirai, H, Thompson, S, Iwasaki, K, Takagi, J. Deposit date: 2016-06-29 Release date: 2017-01-18 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (21 Å) Cite: Conformational Freedom of the LRP6 Ectodomain Is Regulated by N-glycosylation and the Binding of the Wnt Antagonist Dkk1 Cell Rep, 18, 2017

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