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2X11
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Crystal structure of the complete EphA2 ectodomain in complex with ephrin A5 receptor binding domain
分子名称: EPHRIN TYPE-A RECEPTOR 2, EPHRIN-A5
著者Seiradake, E, Harlos, K, Sutton, G, Aricescu, A.R, Jones, E.Y.
登録日2009-12-21
公開日2010-03-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (4.83 Å)
主引用文献An Extracellular Steric Seeding Mechanism for Eph-Ephrin Signalling Platform Assembly
Nat.Struct.Mol.Biol., 17, 2010
4BQ6
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Crystal structure of the RGMB-NEO1 complex form 1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, NEOGENIN, RGM DOMAIN FAMILY MEMBER B
著者Bell, C.H, Healey, E, van Erp, S, Bishop, B, Tang, C, Gilbert, R.J.C, Aricescu, A.R, Pasterkamp, R.J, Siebold, C.
登録日2013-05-30
公開日2013-06-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the Repulsive Guidance Molecule (Rgm)-Neogenin Signaling Hub
Science, 341, 2013
4BQ7
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Crystal structure of the RGMB-Neo1 complex form 2
分子名称: NEOGENIN, RGM DOMAIN FAMILY MEMBER B
著者Bell, C.H, Healey, E, van Erp, S, Bishop, B, Tang, C, Gilbert, R.J.C, Aricescu, A.R, Pasterkamp, R.J, Siebold, C.
登録日2013-05-30
公開日2013-06-12
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (6.601 Å)
主引用文献Structure of the Repulsive Guidance Molecule (Rgm)-Neogenin Signaling Hub
Science, 341, 2013
4BQ8
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Crystal structure of the RGMB-NEO1 complex form 3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, NEOGENIN, RGM DOMAIN FAMILY MEMBER B
著者Bell, C.H, Healey, E, van Erp, S, Bishop, B, Tang, C, Gilbert, R.J.C, Aricescu, A.R, Pasterkamp, R.J, Siebold, C.
登録日2013-05-30
公開日2013-06-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the Repulsive Guidance Molecule (Rgm)-Neogenin Signaling Hub
Science, 341, 2013
2XYC
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BU of 2xyc by Molmil
CRYSTAL STRUCTURE OF NCAM2 IGIV-FN3I
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NEURAL CELL ADHESION MOLECULE 2, ...
著者Kulahin, N, Rasmussen, K.K, Kristensen, O, Berezin, V, Bock, E, Walmod, P.S, Gajhede, M.
登録日2010-11-17
公開日2011-02-23
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structural Model and Trans-Interaction of the Entire Ectodomain of the Olfactory Cell Adhesion Molecule.
Structure, 19, 2011
4ZXB
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BU of 4zxb by Molmil
Structure of the human insulin receptor ectodomain, IRDeltabeta construct, in complex with four Fab molecules
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Croll, T, Smith, B.J, Margetts, M.B, Whittaker, J, Weiss, M.A, Ward, C.W, Lawrence, M.C.
登録日2015-05-20
公開日2016-02-24
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Higher-Resolution Structure of the Human Insulin Receptor Ectodomain: Multi-Modal Inclusion of the Insert Domain.
Structure, 24, 2016
3L5H
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Crystal structure of the full ectodomain of human gp130: New insights into the molecular assembly of receptor complexes
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6 receptor subunit beta, SULFATE ION, ...
著者Xu, Y, Garrett, T.P.J, Zhang, J.G.
登録日2009-12-21
公開日2010-05-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Crystal structure of the entire ectodomain of gp130: insights into the molecular assembly of the tall cytokine receptor complexes.
J.Biol.Chem., 285, 2010
1CN4
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ERYTHROPOIETIN COMPLEXED WITH EXTRACELLULAR DOMAINS OF ERYTHROPOIETIN RECEPTOR
分子名称: PROTEIN (ERYTHROPOIETIN RECEPTOR), PROTEIN (ERYTHROPOIETIN)
著者Stroud, R.M, Reid, S.W.
登録日1999-05-25
公開日1999-08-11
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Efficiency of signalling through cytokine receptors depends critically on receptor orientation.
Nature, 395, 1998
6IAA
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BU of 6iaa by Molmil
hRobo2 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Roundabout homolog 2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Barak, R, Isupov, N.M, Opatowsky, Y.
登録日2018-11-26
公開日2019-03-13
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structural Principles in Robo Activation and Auto-inhibition.
Cell, 177, 2019
3MTR
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BU of 3mtr by Molmil
Crystal structure of the Ig5-FN1 tandem of human NCAM
分子名称: Neural cell adhesion molecule 1, SULFATE ION
著者Lavie, A, Foley, D.A.
登録日2010-04-30
公開日2010-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and mutagenesis of neural cell adhesion molecule domains: evidence for flexibility in the placement of polysialic acid attachment sites
J.Biol.Chem., 285, 2010
3MX0
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BU of 3mx0 by Molmil
Crystal Structure of EphA2 ectodomain in complex with ephrin-A5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-A receptor 2, ...
著者Himanen, J.P, Yermekbayeva, L, Janes, P.W, Walker, J.R, Xu, K, Atapattu, L, Rajashankar, K.R, Mensinga, A, Lackmann, M, Nikolov, D.B, Dhe-Paganon, S.
登録日2010-05-06
公開日2010-06-30
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.506 Å)
主引用文献Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
3N1Q
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Crystal Structure of DhhN bound to CDOFn3
分子名称: CALCIUM ION, Cell adhesion molecule-related/down-regulated by oncogenes, Desert hedgehog protein, ...
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-16
公開日2010-06-02
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
3N1F
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BU of 3n1f by Molmil
Crystal Structure of IhhN bound to CDOFn3
分子名称: CALCIUM ION, Cell adhesion molecule-related/down-regulated by oncogenes, Indian hedgehog protein, ...
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-15
公開日2010-06-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
3N1M
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BU of 3n1m by Molmil
Crystal Structure of IhhN bound to BOCFn3
分子名称: Brother of CDO, CALCIUM ION, Indian hedgehog protein, ...
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-15
公開日2010-06-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
3N1G
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BU of 3n1g by Molmil
Crystal structure of DhhN bound to BOCFn3
分子名称: Brother of CDO, CALCIUM ION, Desert hedgehog protein, ...
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-15
公開日2010-06-02
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
6JK8
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BU of 6jk8 by Molmil
Cryo-EM structure of the full-length human IGF-1R in complex with insulin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin, ...
著者Zhang, X, Yu, D, Wang, T.
登録日2019-02-27
公開日2020-03-04
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Visualization of Ligand-Bound Ectodomain Assembly in the Full-Length Human IGF-1 Receptor by Cryo-EM Single-Particle Analysis.
Structure, 28, 2020
3N1P
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BU of 3n1p by Molmil
Crystal Structure of IhhN bound to BOCFn3
分子名称: Brother of CDO, CALCIUM ION, Indian hedgehog protein, ...
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-16
公開日2010-06-02
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
1EER
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BU of 1eer by Molmil
CRYSTAL STRUCTURE OF HUMAN ERYTHROPOIETIN COMPLEXED TO ITS RECEPTOR AT 1.9 ANGSTROMS
分子名称: ERYTHROPOIETIN, ERYTHROPOIETIN RECEPTOR
著者Syed, R.S, Li, C.
登録日1998-07-24
公開日1999-10-01
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Efficiency of signalling through cytokine receptors depends critically on receptor orientation.
Nature, 395, 1998
1EBA
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BU of 1eba by Molmil
COMPLEX BETWEEN THE EXTRACELLULAR DOMAIN OF ERYTHROPOIETIN (EPO) RECEPTOR [EBP] AND AN INACTIVE PEPTIDE [EMP33] CONTAINS 3,5-DIBROMOTYROSINE IN POSITION 4 (DENOTED DBY)
分子名称: PROTEIN (EPO MIMETICS PEPTIDE 33), PROTEIN (ERYTHROPOIETIN RECEPTOR)
著者Livnah, O, Stura, E.A, Wilson, I.A.
登録日1998-10-02
公開日1998-11-11
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献An antagonist peptide-EPO receptor complex suggests that receptor dimerization is not sufficient for activation.
Nat.Struct.Biol., 5, 1998
1EBP
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BU of 1ebp by Molmil
COMPLEX BETWEEN THE EXTRACELLULAR DOMAIN OF ERYTHROPOIETIN (EPO) RECEPTOR [EBP] AND AN AGONIST PEPTIDE [EMP1]
分子名称: EPO MIMETICS PEPTIDE 1, EPO RECEPTOR
著者Livnah, O, Stura, E.A, Wilson, I.A.
登録日1996-05-07
公開日1997-07-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A.
Science, 273, 1996
1ERN
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BU of 1ern by Molmil
NATIVE STRUCTURE OF THE EXTRACELLULAR DOMAIN OF ERYTHROPOIETIN (EPO) RECEPTOR [EBP]
分子名称: PROTEIN (ERYTHROPOIETIN RECEPTOR)
著者Livnah, O, Stura, E.A, Wilson, I.A.
登録日1999-01-11
公開日2000-01-07
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation.
Science, 283, 1999
3NPZ
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BU of 3npz by Molmil
Prolactin Receptor (PRLR) Complexed with the Natural Hormone (PRL)
分子名称: Prolactin, Prolactin receptor
著者Van Agthoven, J, England, P, Goffin, V, Broutin, I.
登録日2010-06-29
公開日2010-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Structural characterization of the stem-stem dimerization interface between prolactin receptor chains complexed with the natural hormone.
J.Mol.Biol., 404, 2010
1F6F
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CRYSTAL STRUCTURE OF THE TERNARY COMPLEX BETWEEN OVINE PLACENTAL LACTOGEN AND THE EXTRACELLULAR DOMAIN OF THE RAT PROLACTIN RECEPTOR
分子名称: PLACENTAL LACTOGEN, PROLACTIN RECEPTOR
著者Elkins, P.A, Christinger, H.W, Sandowski, Y, Sakal, E, Gertler, A, De Vos, A.M, Kossiakoff, A.A.
登録日2000-06-21
公開日2000-07-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Ternary complex between placental lactogen and the extracellular domain of the prolactin receptor.
Nat.Struct.Biol., 7, 2000
6MOH
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BU of 6moh by Molmil
Dimeric DARPin C_R3 complex with EpoR
分子名称: Dimeric DARPin E2C (C_R3), Erythropoietin receptor, PHOSPHATE ION, ...
著者Jude, K.M, Mohan, K, Garcia, K.C.
登録日2018-10-04
公開日2019-06-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.
Science, 364, 2019
6MOI
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Dimeric DARPin C_angle_R5 complex with EpoR
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Dimeric DARPing CCR5 (C_angle_R5), ...
著者Jude, K.M, Mohan, K, Garcia, K.C, Guo, Y.
登録日2018-10-04
公開日2019-06-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.065 Å)
主引用文献Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.
Science, 364, 2019

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