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7FF8
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BU of 7ff8 by Molmil
Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and Cl(triethylphosphine)gold(I)
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CHLORIDE ION, GOLD ION, ...
Authors:Chew, B.L.A, Luo, D.
Deposit date:2021-07-22
Release date:2022-07-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Inhibitory mechanism of gold analogues against Pseudomonas global virulence factor regulator Vfr
To Be Published
7FF9
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BU of 7ff9 by Molmil
Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and Cl(triethylphosphine)gold(I)
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CHLORIDE ION, GOLD ION, ...
Authors:Chew, B.L.A, Luo, D.
Deposit date:2021-07-23
Release date:2022-07-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Inhibitory mechanism of gold analogues against Pseudomonas global virulence factor regulator Vfr
To Be Published
7FEW
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BU of 7few by Molmil
Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and auranofin gold analogues
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SULFATE ION, cAMP-activated global transcriptional regulator Vfr
Authors:Chew, B.L.A, Luo, D.
Deposit date:2021-07-22
Release date:2022-07-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for the inhibitory mechanism of auranofin and gold(I) analogues against Pseudomonas aeruginosa global virulence factor regulator Vfr.
Comput Struct Biotechnol J, 21, 2023
7FF0
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BU of 7ff0 by Molmil
Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and auranofin
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GOLD ION, SULFATE ION, ...
Authors:Chew, B.L.A, Luo, D.
Deposit date:2021-07-22
Release date:2022-07-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the inhibitory mechanism of auranofin and gold(I) analogues against Pseudomonas aeruginosa global virulence factor regulator Vfr.
Comput Struct Biotechnol J, 21, 2023
7ETS
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BU of 7ets by Molmil
Crystal structure of crp protein from Gardnerella Vaginalis
Descriptor: Crp/Fnr family transcriptional regulator, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Dong, H.J, Wang, S, Zhang, J.M, Gu, L.
Deposit date:2021-05-13
Release date:2022-04-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Crystal structure of crp protein from Gardnerella Vaginalis
To Be Published
2XKO
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BU of 2xko by Molmil
Crystal structure of the complex of NtcA with its transcriptional co- activator PipX
Descriptor: 2-OXOGLUTARIC ACID, GLOBAL NITROGEN REGULATOR, PIPX
Authors:Llacer, J.L, Castells, M.A, Rubio, V.
Deposit date:2010-07-11
Release date:2010-08-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural Basis for the Regulation of Ntca-Dependent Transcription by Proteins Pipx and Pii.
Proc.Natl.Acad.Sci.USA, 107, 2010
2XKP
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BU of 2xkp by Molmil
NtcA from Synechococcus elongatus: active and inactive
Descriptor: 2-OXOGLUTARIC ACID, GLOBAL NITROGEN REGULATOR
Authors:Llacer, J.L, Castells, M.A, Rubio, V.
Deposit date:2010-07-11
Release date:2010-08-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural Basis for the Regulation of Ntca-Dependent Transcription by Proteins Pipx and Pii.
Proc.Natl.Acad.Sci.USA, 107, 2010
2XHK
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BU of 2xhk by Molmil
Crystal structure of transcription factor NtcA from Synechococcus elongatus bound to 2-oxoglutarate
Descriptor: 2-OXOGLUTARIC ACID, GLOBAL NITROGEN REGULATOR
Authors:Llacer, J.L, Castells, M.A, Rubio, V.
Deposit date:2010-06-17
Release date:2010-08-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for the Regulation of Ntca-Dependent Transcription by Proteins Pipx and Pii.
Proc.Natl.Acad.Sci.USA, 107, 2010
2CGP
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BU of 2cgp by Molmil
CATABOLITE GENE ACTIVATOR PROTEIN/DNA COMPLEX, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA (5'-D(*AP*TP*TP*AP*AP*TP*GP*TP*GP*AP*CP*AP*TP*AP*T)-3'), DNA (5'-D(*GP*TP*CP*AP*CP*AP*TP*TP*AP*AP*T)-3'), ...
Authors:Passner, J.M, Steitz, T.A.
Deposit date:1997-01-31
Release date:1998-02-04
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of a CAP-DNA complex having two cAMP molecules bound to each monomer.
Proc.Natl.Acad.Sci.USA, 94, 1997
5FET
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BU of 5fet by Molmil
Crystal Structure of PVX_084705 in presence of Compound 2
Descriptor: 4-[7-[(dimethylamino)methyl]-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-amine, cGMP-dependent protein kinase, putative
Authors:Wernimont, A.K, Tempel, W, Walker, J.R, He, H, Seitova, A, Hills, T, Neculai, A.M, Baker, D.A, Flueck, C, Kettleborough, C.A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hui, R, Hutchinson, A, El Bakkouri, M, Structural Genomics Consortium (SGC)
Deposit date:2015-12-17
Release date:2016-01-13
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.07 Å)
Cite:Crystal Structure of PVX_084705 in presence of Compound 2
To be published
5H3O
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BU of 5h3o by Molmil
Structure of a eukaryotic cyclic nucleotide-gated channel
Descriptor: CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel, SODIUM ION
Authors:Li, M, Zhou, X, Wang, S, Michailidis, I, Gong, Y, Su, D, Li, H, Li, X, Yang, J.
Deposit date:2016-10-26
Release date:2017-01-25
Last modified:2022-03-23
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of a eukaryotic cyclic-nucleotide-gated channel.
Nature, 542, 2017
7LFT
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BU of 7lft by Molmil
Cryo-EM structure of human Apo CNGA1 channel in K+/Ca2+
Descriptor: 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL, POTASSIUM ION, ...
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-01-18
Release date:2021-03-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural mechanisms of gating and selectivity of human rod CNGA1 channel.
Neuron, 109, 2021
7LFX
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BU of 7lfx by Molmil
Cryo-EM structure of human cGMP-bound open CNGA1 channel in Na+/Ca2+
Descriptor: CALCIUM ION, CYCLIC GUANOSINE MONOPHOSPHATE, cGMP-gated cation channel alpha-1
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-01-19
Release date:2021-03-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural mechanisms of gating and selectivity of human rod CNGA1 channel.
Neuron, 109, 2021
7LFW
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BU of 7lfw by Molmil
Cryo-EM structure of human cGMP-bound open CNGA1 channel in K+/Ca2+
Descriptor: CALCIUM ION, CYCLIC GUANOSINE MONOPHOSPHATE, cGMP-gated cation channel alpha-1
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-01-18
Release date:2021-03-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural mechanisms of gating and selectivity of human rod CNGA1 channel.
Neuron, 109, 2021
7LG1
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BU of 7lg1 by Molmil
Cryo-EM structure of human cGMP-bound CNGA1_E365Q channel in Na+/Ca2+
Descriptor: CALCIUM ION, CYCLIC GUANOSINE MONOPHOSPHATE, cGMP-gated cation channel alpha-1
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-01-19
Release date:2021-03-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural mechanisms of gating and selectivity of human rod CNGA1 channel.
Neuron, 109, 2021
7LFY
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BU of 7lfy by Molmil
Cryo-EM structure of human cGMP-bound open CNGA1 channel in Na+
Descriptor: CYCLIC GUANOSINE MONOPHOSPHATE, SODIUM ION, cGMP-gated cation channel alpha-1
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-01-19
Release date:2021-03-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural mechanisms of gating and selectivity of human rod CNGA1 channel.
Neuron, 109, 2021
7LV3
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BU of 7lv3 by Molmil
Crystal structure of human protein kinase G (PKG) R-C complex in inhibited state
Descriptor: 1,2-ETHANEDIOL, Isoform Beta of cGMP-dependent protein kinase 1, MANGANESE (II) ION, ...
Authors:Sharma, R, Lying, Q, Casteel, D, Kim, C.
Deposit date:2021-02-23
Release date:2022-08-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:An auto-inhibited state of protein kinase G and implications for selective activation.
Elife, 11, 2022
5I2D
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BU of 5i2d by Molmil
Crystal structure of T. thermophilus TTHB099 class II transcription activation complex: TAP-RPo
Descriptor: DNA (72-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Feng, Y, Zhang, Y, Ebright, R.H.
Deposit date:2016-02-08
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (4.405 Å)
Cite:Structural basis of transcription activation.
Science, 352, 2016
2FMY
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BU of 2fmy by Molmil
CO-dependent transcription factor CooA from Carboxydothermus hydrogenoformans (Imidazole-bound form)
Descriptor: IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, carbon monoxide oxidation system transcription regulator CooA-1
Authors:Higuchi, Y, Komori, H.
Deposit date:2006-01-10
Release date:2007-01-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of CO-sensing Transcription Activator CooA Bound to Exogenous Ligand Imidazole
J.Mol.Biol., 367, 2007
4AVC
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BU of 4avc by Molmil
Crystal structure of protein lysine acetyltransferase Rv0998 in complex with acetyl CoA and cAMP
Descriptor: 1,2-ETHANEDIOL, ACETYL COENZYME *A, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ...
Authors:Lee, H.J, Lang, P.T, Fortune, S.M, Sassetti, C.M, Alber, T.
Deposit date:2012-05-24
Release date:2012-07-11
Last modified:2012-08-22
Method:X-RAY DIFFRACTION (2.806 Å)
Cite:Cyclic AMP Regulation of Protein Lysine Acetylation in Mycobacterium Tuberculosis.
Nat.Struct.Mol.Biol., 19, 2012
2GAU
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BU of 2gau by Molmil
Crystal structure of transcriptional regulator, Crp/Fnr family from Porphyromonas gingivalis (APC80792), Structural genomics, MCSG
Descriptor: transcriptional regulator, Crp/Fnr family
Authors:Rotella, F.J, Zhang, R.G, Mulligan, R, Moy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2006-03-09
Release date:2006-04-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The 1.9-A crystal structure of transcriptional regulator, Crp/Fnr family from Porphyromonas gingivalis
To be Published
4BH9
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BU of 4bh9 by Molmil
A structural model of CAP mutant (T127L and S128I) in the apo state
Descriptor: cAMP-activated global transcriptional regulator CRP
Authors:Tzeng, S.R, Kalodimos, C.G.
Deposit date:2013-03-30
Release date:2013-05-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Allosteric inhibition through suppression of transient conformational states.
Nat. Chem. Biol., 9, 2013
4BHP
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BU of 4bhp by Molmil
A structural model of CAP mutant (T127L and S128I) in cGMP-bound state
Descriptor: CAMP RECEPTOR PROTEIN
Authors:Tzeng, S.R, Kalodimos, C.G.
Deposit date:2013-04-04
Release date:2013-05-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Allosteric Inhibition Through Suppression of Transient Conformational States.
Nat.Chem.Biol., 9, 2013
2GZW
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BU of 2gzw by Molmil
Crystal structure of the E.coli CRP-cAMP complex
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator
Authors:Kumarevel, T.S, Tanaka, T, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-05-12
Release date:2007-05-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal structure of activated CRP protein from E coli
To be Published
4AVB
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BU of 4avb by Molmil
Crystal structure of protein lysine acetyltransferase Rv0998 in complex with acetyl CoA and cAMP
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, ACETYL COENZYME *A, ...
Authors:Lee, H.J, Lang, P.T, Fortune, S.M, Sassetti, C.M, Alber, T.
Deposit date:2012-05-24
Release date:2012-07-11
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Cyclic AMP Regulation of Protein Lysine Acetylation in Mycobacterium Tuberculosis.
Nat.Struct.Mol.Biol., 19, 2012

220113

數據於2024-05-22公開中

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