7LV3

Crystal structure of human protein kinase G (PKG) R-C complex in inhibited state

Summary for 7LV3

Entry DOI	10.2210/pdb7lv3/pdb
Descriptor	Isoform Beta of cGMP-dependent protein kinase 1, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total)
Functional Keywords	protein kinase g, transferase-inhibitor complex, transferase/inhibitor
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	141141.43
Authors	Sharma, R.,Lying, Q.,Casteel, D.,Kim, C. (deposition date: 2021-02-23, release date: 2022-08-24, Last modification date: 2023-10-18)
Primary citation	Sharma, R.,Kim, J.J.,Qin, L.,Henning, P.,Akimoto, M.,VanSchouwen, B.,Kaur, G.,Sankaran, B.,MacKenzie, K.R.,Melacini, G.,Casteel, D.E.,Herberg, F.W.,Kim, C.W. An auto-inhibited state of protein kinase G and implications for selective activation. Elife, 11:-, 2022 Cited by PubMed: 35929723 DOI: 10.7554/eLife.79530 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.41 Å)

Structure validation