7FF0

Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and auranofin

Summary for 7FF0

Entry DOI	10.2210/pdb7ff0/pdb
Descriptor	cAMP-activated global transcriptional regulator Vfr, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SULFATE ION, ... (5 entities in total)
Functional Keywords	cyclic amp receptor protein, dna binding protein
Biological source	Pseudomonas aeruginosa PAO1
Total number of polymer chains	2
Total formula weight	49463.15
Authors	Chew, B.L.A.,Luo, D. (deposition date: 2021-07-22, release date: 2022-07-27, Last modification date: 2024-02-07)
Primary citation	Zhang, Y.,Chew, B.L.A.,Wang, J.,Yuan, M.,Yam, J.K.H.,Luo, D.,Yang, L. Structural basis for the inhibitory mechanism of auranofin and gold(I) analogues against Pseudomonas aeruginosa global virulence factor regulator Vfr. Comput Struct Biotechnol J, 21:2137-2146, 2023 Cited by PubMed: 37007650 DOI: 10.1016/j.csbj.2023.03.013 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation