PDB: 230 resultsInfo pagesStatus searchChemie searchBIRD

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2WP1	Structure of Brdt bromodomain 2 bound to an acetylated histone H3 peptide Descriptor: BROMODOMAIN TESTIS-SPECIFIC PROTEIN, HISTONE H3 Authors: Moriniere, J, Rousseaux, S, Steuerwald, U, Soler-Lopez, M, Curtet, S, Vitte, A.-L, Govin, J, Gaucher, J, Sadoul, K, Hart, D.J, Krijgsveld, J, Khochbin, S, Mueller, C.W, Petosa, C. Deposit date: 2009-08-02 Release date: 2009-09-22 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Cooperative Binding of Two Acetylation Marks on a Histone Tail by a Single Bromodomain. Nature, 461, 2009
3GAT	SOLUTION NMR STRUCTURE OF THE C-TERMINAL DOMAIN OF CHICKEN GATA-1 BOUND TO DNA, 34 STRUCTURES Descriptor: DNA (5'-D(*AP*AP*TP*GP*TP*TP*TP*AP*TP*CP*TP*GP*CP*AP*AP*C)-3'), DNA (5'-D(*GP*TP*TP*GP*CP*AP*GP*AP*TP*AP*AP*AP*CP*AP*TP*T)-3'), ERYTHROID TRANSCRIPTION FACTOR GATA-1, ... Authors: Clore, G.M, Tjandra, N, Starich, M, Omichinski, J.G, Gronenborn, A.M. Deposit date: 1997-11-07 Release date: 1998-01-28 Last modified: 2022-03-16 Method: SOLUTION NMR Cite: Use of dipolar 1H-15N and 1H-13C couplings in the structure determination of magnetically oriented macromolecules in solution. Nat.Struct.Biol., 4, 1997
1TAC	HIV-1 TAT CYS-, NMR, 10 STRUCTURES Descriptor: TAT PROTEIN Authors: Roesch, P, Boehm, M, Sticht, H. Deposit date: 1998-03-13 Release date: 1999-03-23 Last modified: 2021-11-03 Method: SOLUTION NMR Cite: Solution Structure of HIV-1 Tat Protein To be Published
1TIV	STRUCTURAL STUDIES OF HIV-1 TAT PROTEIN Descriptor: HIV-1 TRANSACTIVATOR PROTEIN Authors: Bayer, P, Kraft, M, Frank, R, Roesch, P. Deposit date: 1995-02-14 Release date: 1995-07-31 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: Structural studies of HIV-1 Tat protein. J.Mol.Biol., 247, 1995
1TBC	HIV-1 TAT, NMR, 10 STRUCTURES Descriptor: TAT PROTEIN Authors: Roesch, P, Boehm, M, Sticht, H. Deposit date: 1998-03-13 Release date: 1999-03-23 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: Solution Structure of HIV-1 Tat Protein To be Published
8CDK	CAND1 b-hairpin++-SCF-SKP2 CAND1 partly engaged SCF partly rocked Descriptor: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ... Authors: Baek, K, Schulman, B.A. Deposit date: 2023-01-31 Release date: 2023-04-19 Last modified: 2023-05-10 Method: ELECTRON MICROSCOPY (3.32 Å) Cite: Systemwide disassembly and assembly of SCF ubiquitin ligase complexes. Cell, 186, 2023
8CCW	Crystal structure of human Sirt3 in complex with an acetylated HIV1 Tat-46-54 substrate peptide Descriptor: NAD-dependent protein deacetylase sirtuin-3, mitochondrial, Protein Tat, ... Authors: Adolph, R.S, Steegborn, C. Deposit date: 2023-01-27 Release date: 2023-05-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Molecular Mechanism of Sirtuin 1 Inhibition by Human Immunodeficiency Virus 1 Tat Protein. Life, 13, 2023
8CCZ	Crystal structure of human Sirt3 in complex with an inhibiting HIV1 Tat-37-59 peptide Descriptor: NAD-dependent protein deacetylase sirtuin-3, mitochondrial, Protein Tat, ... Authors: Adolph, R.S, Steegborn, C. Deposit date: 2023-01-28 Release date: 2023-05-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Molecular Mechanism of Sirtuin 1 Inhibition by Human Immunodeficiency Virus 1 Tat Protein. Life, 13, 2023
6MCF	Solution structure of 7SK stem-loop 1 with HIV-1 Tat RNA Binding Domain Descriptor: 7SK Stem-loop 1 RNA, Protein Tat Authors: Pham, V.V, D'Souza, V.M. Deposit date: 2018-08-31 Release date: 2018-10-31 Last modified: 2019-11-20 Method: SOLUTION NMR Cite: HIV-1 Tat interactions with cellular 7SK and viral TAR RNAs identifies dual structural mimicry. Nat Commun, 9, 2018
6MCE	Solution structure of HIV-1 TAR with Tat RNA Binding Domain Descriptor: Protein Tat, TAR RNA Authors: Pham, V.V, D'Souza, V.M. Deposit date: 2018-08-31 Release date: 2018-10-31 Last modified: 2019-11-20 Method: SOLUTION NMR Cite: HIV-1 Tat interactions with cellular 7SK and viral TAR RNAs identifies dual structural mimicry. Nat Commun, 9, 2018
1NFI	I-KAPPA-B-ALPHA/NF-KAPPA-B COMPLEX Descriptor: I-KAPPA-B-ALPHA, NF-KAPPA-B P50, NF-KAPPA-B P65 Authors: Jacobs, M.D, Harrison, S.C. Deposit date: 1998-08-25 Release date: 1998-11-18 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure of an IkappaBalpha/NF-kappaB complex. Cell(Cambridge,Mass.), 95, 1998
1DSZ	STRUCTURE OF THE RXR/RAR DNA-BINDING DOMAIN HETERODIMER IN COMPLEX WITH THE RETINOIC ACID RESPONSE ELEMENT DR1 Descriptor: DNA (5'-D(*CP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*G)-3'), RETINOIC ACID RECEPTOR ALPHA, ... Authors: Rastinejad, F, Wagner, T, Zhao, Q, Khorasanizadeh, S. Deposit date: 2000-01-10 Release date: 2000-07-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structure of the RXR-RAR DNA-binding complex on the retinoic acid response element DR1. EMBO J., 19, 2000
2GAT	SOLUTION STRUCTURE OF THE C-TERMINAL DOMAIN OF CHICKEN GATA-1 BOUND TO DNA, NMR, REGULARIZED MEAN STRUCTURE Descriptor: DNA (5'-D(*AP*AP*TP*GP*TP*TP*TP*AP*TP*CP*TP*GP*CP*AP*AP*C)-3'), DNA (5'-D(*GP*TP*TP*GP*CP*AP*GP*AP*TP*AP*AP*AP*CP*AP*TP*T)-3'), ERYTHROID TRANSCRIPTION FACTOR GATA-1, ... Authors: Clore, G.M, Tjandra, N, Starich, M, Omichinski, J.G, Gronenborn, A.M. Deposit date: 1997-11-07 Release date: 1998-01-28 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: Use of dipolar 1H-15N and 1H-13C couplings in the structure determination of magnetically oriented macromolecules in solution. Nat.Struct.Biol., 4, 1997
1E9N	A second divalent metal ion in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1, and its implications for the catalytic mechanism Descriptor: DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE, LEAD (II) ION Authors: Beernink, P.T, Segelke, B.W, Rupp, B. Deposit date: 2000-10-24 Release date: 2001-02-16 Last modified: 2019-05-08 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Two Divalent Metal Ions in the Active Site of a New Crystal Form of Human Apurinic/Apyrimidinic Endonuclease, Ape1: Implications for the Catalytic Mechanism J.Mol.Biol., 307, 2001
4NQA	Crystal structure of liganded hRXR-alpha/hLXR-beta heterodimer on DNA Descriptor: (9cis)-retinoic acid, 5'-D(*TP*AP*AP*GP*GP*TP*CP*AP*CP*TP*TP*CP*AP*GP*GP*TP*CP*A)-3', 5'-D(*TP*AP*TP*GP*AP*CP*CP*TP*GP*AP*AP*GP*TP*GP*AP*CP*CP*T)-3', ... Authors: Lou, X.H, Toresson, G, Benod, C, Suh, J.H, Phillips, K.J, Webb, P, Gustafsson, J.A. Deposit date: 2013-11-24 Release date: 2014-02-26 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.102 Å) Cite: Structure of the retinoid X receptor alpha-liver X receptor beta (RXR alpha-LXR beta ) heterodimer on DNA. Nat.Struct.Mol.Biol., 21, 2014
2ISI	Crystal structure of Ape1 from Homo sapiens in a new crystal form complexed with a ligand Descriptor: DNA-(apurinic or apyrimidinic site) lyase, MAGNESIUM ION, PHOSPHATE ION Authors: Agarwal, R, Naidu, M.D. Deposit date: 2006-10-17 Release date: 2006-10-31 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.76 Å) Cite: Crystal structure of hApe1 in a new crystal form with a bound ligand: implications on catalytic mechanism and its inhibition To be Published
4OR5	Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4 Descriptor: AF4/FMR2 family member 4, Cyclin-T1, Cyclin-dependent kinase 9, ... Authors: Gu, J, Babayeva, N.D, Suwa, Y, Baranovskiy, A.G, Price, D.H, Tahirov, T.H. Deposit date: 2014-02-10 Release date: 2014-04-16 Last modified: 2014-06-11 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4. Cell Cycle, 13, 2014
1GAT	SOLUTION STRUCTURE OF THE SPECIFIC DNA COMPLEX OF THE ZINC CONTAINING DNA BINDING DOMAIN OF THE ERYTHROID TRANSCRIPTION FACTOR GATA-1 BY MULTIDIMENSIONAL NMR Descriptor: DNA (5'-D(P*AP*GP*AP*TP*AP*AP*AP*C)3'), DNA (5'-D(P*GP*TP*TP*TP*AP*TP*CP*T)-3'), ERYTHROID TRANSCRIPTION FACTOR GATA-1, ... Authors: Clore, G.M, Omichinski, J.G, Gronenborn, A.M. Deposit date: 1993-06-28 Release date: 1993-10-31 Last modified: 2012-09-05 Method: SOLUTION NMR Cite: NMR structure of a specific DNA complex of Zn-containing DNA binding domain of GATA-1. Science, 261, 1993
1R0N	Crystal Structure of Heterodimeric Ecdsyone receptor DNA binding complex Descriptor: Ecdsyone Response Element, Ecdysone Response Element, Ecdysone receptor, ... Authors: Devarakonda, S, Harp, J.M, Kim, Y, Ozyhar, A, Rastinejad, F. Deposit date: 2003-09-22 Release date: 2003-10-21 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure of the heterodimeric Ecdysone Receptor DNA-binding complex Embo J., 22, 2003
4OGR	crystal structure of P-TEFb complex with AFF4 and Tat Descriptor: ADENOSINE, AF4/FMR2 family member 4, Cyclin-T1, ... Authors: Schulze-Gahmen, U, Alber, T. Deposit date: 2014-01-16 Release date: 2014-05-07 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3 Å) Cite: AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter. Elife, 3, 2014
1GAU	SOLUTION STRUCTURE OF THE SPECIFIC DNA COMPLEX OF THE ZINC CONTAINING DNA BINDING DOMAIN OF THE ERYTHROID TRANSCRIPTION FACTOR GATA-1 BY MULTIDIMENSIONAL NMR Descriptor: DNA (5'-D(P*AP*GP*AP*TP*AP*AP*AP*C)-3'), DNA (5'-D(P*GP*TP*TP*TP*AP*TP*CP*T)-3'), ERYTHROID TRANSCRIPTION FACTOR GATA-1 Authors: Clore, G.M, Omichinski, J.G, Gronenborn, A.M. Deposit date: 1993-06-28 Release date: 1993-10-31 Last modified: 2012-09-05 Method: SOLUTION NMR Cite: NMR structure of a specific DNA complex of Zn-containing DNA binding domain of GATA-1. Science, 261, 1993
1GNF	SOLUTION STRUCTURE OF THE N-TERMINAL ZINC FINGER OF MURINE GATA-1, NMR, 25 STRUCTURES Descriptor: TRANSCRIPTION FACTOR GATA-1, ZINC ION Authors: Kowalski, K, Czolij, R, King, G.F, Crossley, M, Mackay, J.P. Deposit date: 1998-10-12 Release date: 1999-06-08 Last modified: 2017-11-29 Method: SOLUTION NMR Cite: The solution structure of the N-terminal zinc finger of GATA-1 reveals a specific binding face for the transcriptional co-factor FOG. J.Biomol.NMR, 13, 1999
1HD7	A Second Divalent Metal Ion in the Active Site of a New Crystal Form of Human Apurinic/Apyridinimic Endonuclease, Ape1, and its Implications for the Catalytic Mechanism Descriptor: DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE, LEAD (II) ION Authors: Beernink, P.T, Segelke, B.W, Rupp, B. Deposit date: 2000-11-09 Release date: 2001-02-16 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Two Divalent Metal Ions in the Active Site of a New Crystal Form of Human Apurinic/Apyrimidinic Endonuclease, Ape1: Implications for the Catalytic Mechanism J.Mol.Biol., 307, 2001
1RAM	A NOVEL DNA RECOGNITION MODE BY NF-KB P65 HOMODIMER Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, DNA (5'-D(*CP*GP*GP*CP*TP*GP*GP*AP*AP*AP*TP*TP*TP*CP*CP*AP*GP*CP*CP*G)-3'), PROTEIN (TRANSCRIPTION FACTOR NF-KB P65) Authors: Chen, Y.-Q, Ghosh, S, Ghosh, G. Deposit date: 1997-11-22 Release date: 1998-05-27 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.7 Å) Cite: A novel DNA recognition mode by the NF-kappa B p65 homodimer. Nat.Struct.Biol., 5, 1998
1RXR	HIGH RESOLUTION SOLUTION STRUCTURE OF THE RETINOID X RECEPTOR DNA BINDING DOMAIN, NMR, 20 STRUCTURE Descriptor: RETINOIC ACID RECEPTOR-ALPHA, ZINC ION Authors: Holmbeck, S.M.A, Foster, M.P, Casimiro, D.R, Sem, D.S, Dyson, H.J, Wright, P.E. Deposit date: 1998-06-12 Release date: 1998-11-11 Last modified: 2018-03-14 Method: SOLUTION NMR Cite: High-resolution solution structure of the retinoid X receptor DNA-binding domain. J.Mol.Biol., 281, 1998

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