2ISI

Crystal structure of Ape1 from Homo sapiens in a new crystal form complexed with a ligand

Summary for 2ISI

• Entry DOI: 10.2210/pdb2isi/pdb
• Related: 1DE8 1DE9 1DEW 1E9N 1HD7
• Descriptor: DNA-(apurinic or apyrimidinic site) lyase, PHOSPHATE ION, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: ape1, magnesium, lyase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus. DNA-(apurinic or apyrimidinic site) lyase, mitochondrial: Mitochondrion: P27695
• Total number of polymer chains: 3
• Total formula weight: 106688.74

Authors

Agarwal, R.,Naidu, M.D. (deposition date: 2006-10-17, release date: 2006-10-31, Last modification date: 2023-08-30)

• Primary citation: Agarwal, R.,Naidu, M.D.; Crystal structure of hApe1 in a new crystal form with a bound ligand: implications on catalytic mechanism and its inhibition; To be Published,

Experimental method

X-RAY DIFFRACTION (2.76 Å)