4OR5

Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4

Summary for 4OR5

Entry DOI	10.2210/pdb4or5/pdb
Descriptor	Cyclin-dependent kinase 9, Cyclin-T1, Protein Tat, ... (8 entities in total)
Functional Keywords	cdk9, tat, aff4, zinc finger, transcription, rna binding, phosphorylation, transferase-transcription complex, transferase/transcription
Biological source	Homo sapiens (human) More
Cellular location	Nucleus: P50750 O60563 Q9UHB7 Host nucleus, host nucleolus: P04608
Total number of polymer chains	8
Total formula weight	159543.94
Authors	Gu, J.,Babayeva, N.D.,Suwa, Y.,Baranovskiy, A.G.,Price, D.H.,Tahirov, T.H. (deposition date: 2014-02-10, release date: 2014-04-16, Last modification date: 2014-06-11)
Primary citation	Gu, J.,Babayeva, N.D.,Suwa, Y.,Baranovskiy, A.G.,Price, D.H.,Tahirov, T.H. Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4. Cell Cycle, 13:1788-1797, 2014 Cited by PubMed: 24727379 DOI: 10.4161/cc.28756 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation