4F4L
| Open Channel Conformation of a Voltage Gated Sodium Channel | 分子名称: | Ion transport protein | 著者 | McCusker, E.C, Bagneris, C, Naylor, C.E, Cole, A.R, D'Avanzo, N, Nichols, C.G, Wallace, B.A. | 登録日 | 2012-05-10 | 公開日 | 2012-10-03 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.49 Å) | 主引用文献 | Structure of a bacterial voltage-gated sodium channel pore reveals mechanisms of opening and closing. Nat Commun, 3, 2012
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5OQK
| Solution NMR structure of truncated, human Hv1/VSOP (Voltage-gated proton channel) | 分子名称: | Voltage-gated hydrogen channel 1 | 著者 | Bayrhuber, M, Maslennikov, I, Kwiatowski, W, Sobol, A, Wierschem, C, Eichmann, C, Riek, R. | 登録日 | 2017-08-12 | 公開日 | 2019-04-03 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Nuclear Magnetic Resonance Solution Structure and Functional Behavior of the Human Proton Channel. Biochemistry, 58, 2019
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2KYH
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2A0L
| Crystal structure of KvAP-33H1 Fv complex | 分子名称: | 33H1 Fv fragment, POTASSIUM ION, Voltage-gated potassium channel | 著者 | Lee, S.Y, Lee, A, Chen, J, Mackinnon, R. | 登録日 | 2005-06-16 | 公開日 | 2005-11-01 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | Structure of the KvAP voltage-dependent K+ channel and its dependence on the lipid membrane. Proc.Natl.Acad.Sci.Usa, 102, 2005
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3ZJZ
| Open-form NavMS Sodium Channel Pore (with C-terminal Domain) | 分子名称: | DODECAETHYLENE GLYCOL, HEGA-10, ION TRANSPORT PROTEIN, ... | 著者 | Bagneris, C, Naylor, C.E, Wallace, B.A. | 登録日 | 2013-01-21 | 公開日 | 2013-10-02 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | 主引用文献 | Role of the C-Terminal Domain in the Structure and Function of Tetrameric Sodium Channels. Nat.Commun., 4, 2013
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4G7V
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4G7Y
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4G80
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4X8A
| NavMS pore and C-terminal domain grown from protein purified in LiCl | 分子名称: | HEGA-10, Ion transport protein, NONAETHYLENE GLYCOL, ... | 著者 | Naylor, C.E, Bagneris, C, Wallace, B.A. | 登録日 | 2014-12-10 | 公開日 | 2016-03-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | 主引用文献 | Molecular basis of ion permeability in a voltage-gated sodium channel. Embo J., 35, 2016
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3RVZ
| Crystal structure of the NavAb voltage-gated sodium channel (Ile217Cys, 2.8 A) | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein | 著者 | Payandeh, J, Scheuer, T, Zheng, N, Catterall, W.A. | 登録日 | 2011-05-06 | 公開日 | 2011-07-13 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The crystal structure of a voltage-gated sodium channel. Nature, 475, 2011
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4X88
| E178D Selectivity filter mutant of NavMS voltage-gated pore | 分子名称: | HEGA-10, Ion transport protein, PENTAETHYLENE GLYCOL, ... | 著者 | Naylor, C.E, Bagneris, C, Wallace, B.A. | 登録日 | 2014-12-10 | 公開日 | 2016-02-24 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Molecular basis of ion permeability in a voltage-gated sodium channel. Embo J., 35, 2016
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4X89
| NavMs voltage-gated sodium channal pore and C-terminal domain soaked with Silver nitrate | 分子名称: | HEGA-10, Ion transport protein, PENTAETHYLENE GLYCOL, ... | 著者 | Naylor, C.E, Bagneris, C, Wallace, B.A. | 登録日 | 2014-12-10 | 公開日 | 2016-03-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Molecular basis of ion permeability in a voltage-gated sodium channel. Embo J., 35, 2016
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3RW0
| Crystal structure of the NavAb voltage-gated sodium channel (Met221Cys, 2.95 A) | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein | 著者 | Payandeh, J, Scheuer, T, Zheng, N, Catterall, W.A. | 登録日 | 2011-05-06 | 公開日 | 2011-07-13 | 最終更新日 | 2011-07-27 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | The crystal structure of a voltage-gated sodium channel. Nature, 475, 2011
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3RVY
| Crystal structure of the NavAb voltage-gated sodium channel (Ile217Cys, 2.7 A) | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein | 著者 | Payandeh, J, Scheuer, T, Zheng, N, Catterall, W.A. | 登録日 | 2011-05-06 | 公開日 | 2011-07-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The crystal structure of a voltage-gated sodium channel. Nature, 475, 2011
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5BZB
| NavMs voltage-gated sodium channel pore and C-terminal domain | 分子名称: | DODECAETHYLENE GLYCOL, HEGA-10, Ion transport protein, ... | 著者 | Naylor, C.E, Bagneris, C, Wallace, B.A. | 登録日 | 2015-06-11 | 公開日 | 2016-02-24 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Molecular basis of ion permeability in a voltage-gated sodium channel. Embo J., 35, 2016
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6KZP
| calcium channel-ligand | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Yan, N. | 登録日 | 2019-09-25 | 公開日 | 2019-12-18 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM structures of apo and antagonist-bound human Cav3.1. Nature, 576, 2019
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6KZO
| membrane protein | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Yan, N. | 登録日 | 2019-09-25 | 公開日 | 2019-12-18 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structures of apo and antagonist-bound human Cav3.1. Nature, 576, 2019
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5DQQ
| Structure, inhibition and regulation of two-pore channel TPC1 from Arabidopsis thaliana | 分子名称: | CALCIUM ION, PALMITIC ACID, Two pore calcium channel protein 1, ... | 著者 | Kintzer, A.F, Stroud, R.M. | 登録日 | 2015-09-15 | 公開日 | 2016-03-09 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.872 Å) | 主引用文献 | Structure, inhibition and regulation of two-pore channel TPC1 from Arabidopsis thaliana Nature, 531, 2016
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5EK0
| Human Nav1.7-VSD4-NavAb in complex with GX-936. | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-cyano-4-[2-[2-(1-ethylazetidin-3-yl)pyrazol-3-yl]-4-(trifluoromethyl)phenoxy]-~{N}-(1,2,4-thiadiazol-5-yl)benzenesulfonamide, Chimera of bacterial Ion transport protein and human Sodium channel protein type 9 subunit alpha | 著者 | Ahuja, S, Mukund, S, Starovasnik, M.A, Koth, C.M, Payandeh, J. | 登録日 | 2015-11-03 | 公開日 | 2015-12-23 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.53 Å) | 主引用文献 | Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonist. Science, 350, 2015
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5E1J
| Structure of voltage-gated two-pore channel TPC1 from Arabidopsis thaliana | 分子名称: | BARIUM ION, CALCIUM ION, Two pore calcium channel protein 1 | 著者 | Guo, J, Zeng, W, Chen, Q, Lee, C, Chen, L, Yang, Y, Jiang, Y. | 登録日 | 2015-09-29 | 公開日 | 2015-12-16 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.308 Å) | 主引用文献 | Structure of the voltage-gated two-pore channel TPC1 from Arabidopsis thaliana. Nature, 531, 2016
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6XIW
| Cryo-EM structure of the sodium leak channel NALCN-FAM155A complex | 分子名称: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kschonsak, M, Chua, H.C, Noland, C.L, Weidling, C, Clairfeuille, T, Bahlke, O.O, Ameen, A.O, Li, Z.R, Arthur, C.P, Ciferri, C, Pless, S.A, Payandeh, J. | 登録日 | 2020-06-22 | 公開日 | 2020-07-29 | 最終更新日 | 2020-11-25 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structure of the human sodium leak channel NALCN. Nature, 587, 2020
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6YZ0
| Full length Open-form Sodium Channel NavMs F208L in complex with Cannabidiol (CBD) | 分子名称: | 2-[(1R,2R,5S)-5-methyl-2-(prop-1-en-2-yl)cyclohexyl]-5-pentylbenzene-1,3-diol, DODECAETHYLENE GLYCOL, HEGA-10, ... | 著者 | Sula, A, Sait, L.G, Hollingworth, D, Wallace, B.A. | 登録日 | 2020-05-06 | 公開日 | 2020-11-11 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Cannabidiol interactions with voltage-gated sodium channels. Elife, 9, 2020
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6YZ2
| Full length Open-form Sodium Channel NavMs F208L | 分子名称: | DODECAETHYLENE GLYCOL, HEGA-10, Ion transport protein, ... | 著者 | Sula, A, Sait, L.G, Hollingworth, D, Wallace, B.A. | 登録日 | 2020-05-06 | 公開日 | 2020-11-11 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Cannabidiol interactions with voltage-gated sodium channels. Elife, 9, 2020
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6Z8C
| Crystal Structure of the Voltage-Gated Sodium Channel NavMs (F208L) in complex with N-desmethyltamoxifen (3.2 A resolution) | 分子名称: | 2-[4-[(~{Z})-1,2-diphenylbut-1-enyl]phenoxy]-~{N}-methyl-ethanamine, DODECAETHYLENE GLYCOL, HEGA-10, ... | 著者 | Sula, A, Hollingworth, D, Wallace, B.A. | 登録日 | 2020-06-02 | 公開日 | 2021-02-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | A tamoxifen receptor within a voltage-gated sodium channel. Mol.Cell, 81, 2021
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4MVR
| Structural Basis for Ca2+ Selectivity of a Voltage-gated Calcium Channel | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein, MANGANESE (II) ION | 著者 | Tang, L, Gamal El-Din, T.M, Payandeh, J, Gilbert, Q.M, Heard, T.M, Scheuer, T, Zheng, N, Catterall, W.A. | 登録日 | 2013-09-24 | 公開日 | 2013-11-27 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.196 Å) | 主引用文献 | Structural basis for Ca2+ selectivity of a voltage-gated calcium channel. Nature, 505, 2014
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