7XY7
| Adenosine receptor bound to a non-selective agonist in complex with a G protein obtained by cryo-EM | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Zhang, J.Y, Chen, Y, Hua, T, Song, G.J. | 登録日 | 2022-05-31 | 公開日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | Cryo-EM structure of the human adenosine A 2B receptor-G s signaling complex. Sci Adv, 8, 2022
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7XY6
| Adenosine receptor bound to an agonist in complex with G protein obtained by cryo-EM | 分子名称: | 2-[6-azanyl-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]pyridin-2-yl]sulfanylethanamide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhang, J.Y, Chen, Y, Hua, T, Song, G.J. | 登録日 | 2022-05-31 | 公開日 | 2023-05-03 | 最終更新日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | 主引用文献 | Cryo-EM structure of the human adenosine A 2B receptor-G s signaling complex. Sci Adv, 8, 2022
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7Y1F
| Cryo-EM structure of human k-opioid receptor-Gi complex | 分子名称: | Dynorphin, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Chen, B.O, Xu, F.E. | 登録日 | 2022-06-08 | 公開日 | 2023-05-24 | 最終更新日 | 2023-06-21 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structure of human kappa-opioid receptor-Gi complex bound to an endogenous agonist dynorphin A. Protein Cell, 14, 2023
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7XXH
| Cryo-EM structure of the purinergic receptor P2Y1R in complex with 2MeSADP and G11 | 分子名称: | 2-(methylsulfanyl)adenosine 5'-(trihydrogen diphosphate), Guanine nucleotide-binding protein G(11) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Tan, Q, Li, B, Han, S, Zhao, Q, Wu, B. | 登録日 | 2022-05-30 | 公開日 | 2023-06-07 | 最終更新日 | 2023-09-20 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural insights into signal transduction of the purinergic receptors P2Y1R and P2Y12R. Protein Cell, 14, 2023
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7Y3G
| Cryo-EM structure of a class A orphan GPCR | 分子名称: | G-protein coupled receptor 12, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Liu, Z.J, Hua, T, Li, H, Zhang, J.Y, Luo, F. | 登録日 | 2022-06-10 | 公開日 | 2023-06-07 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Structural insight into the constitutive activity of human orphan receptor GPR12. Sci Bull (Beijing), 68, 2023
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7XXI
| Cryo-EM structure of the purinergic receptor P2Y12R in complex with 2MeSADP and Gi | 分子名称: | 2-(methylsulfanyl)adenosine 5'-(trihydrogen diphosphate), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Tan, Q, Li, B, Han, S, Zhao, Q, Wu, B. | 登録日 | 2022-05-30 | 公開日 | 2023-06-07 | 最終更新日 | 2023-09-20 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural insights into signal transduction of the purinergic receptors P2Y1R and P2Y12R. Protein Cell, 14, 2023
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7YDM
| Cryo-EM structure of CD97/Gq complex | 分子名称: | Adhesion G protein-coupled receptor E5 subunit beta, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | He, Y, Wang, N. | 登録日 | 2022-07-04 | 公開日 | 2023-07-12 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | 主引用文献 | Structural basis of CD97 activation and G-protein coupling. Cell Chem Biol, 30, 2023
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7YDH
| Cryo EM structure of CD97/miniG13 complex | 分子名称: | Adhesion G protein-coupled receptor E5 subunit beta, G protein subunit 13 (Gi2-mini-G13 chimera), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | He, Y, Wang, N. | 登録日 | 2022-07-04 | 公開日 | 2023-07-12 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of CD97 activation and G-protein coupling. Cell Chem Biol, 30, 2023
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7YDP
| Cryo-EM structure of CD97/miniGs complex | 分子名称: | Adhesion G protein-coupled receptor E5 subunit beta, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | He, Y, Wang, N. | 登録日 | 2022-07-04 | 公開日 | 2023-07-12 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of CD97 activation and G-protein coupling. Cell Chem Biol, 30, 2023
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7YDJ
| Cryo EM structure of CD97/miniG12 complex | 分子名称: | Adhesion G protein-coupled receptor E5 subunit beta, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | He, Y, Wang, N. | 登録日 | 2022-07-04 | 公開日 | 2023-07-12 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | Cryo EM structure of CD97/miniG12 complex To Be Published
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7YFC
| Cryo-EM structure of the histamine-bound histamine H4 receptor and Gq complex | 分子名称: | CHOLESTEROL, Engineered G-alpha-q, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Im, D, Iwata, S, Asada, H. | 登録日 | 2022-07-08 | 公開日 | 2023-10-25 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural insights into the agonists binding and receptor selectivity of human histamine H 4 receptor. Nat Commun, 14, 2023
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7YFD
| Cryo-EM structure of the imetit-bound histamine H4 receptor and Gq complex | 分子名称: | 2-(1~{H}-imidazol-5-yl)ethyl carbamimidothioate, CHOLESTEROL, Engineered G-alpha-q, ... | 著者 | Im, D, Iwata, S, Asada, H. | 登録日 | 2022-07-08 | 公開日 | 2023-10-25 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into the agonists binding and receptor selectivity of human histamine H 4 receptor. Nat Commun, 14, 2023
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7YP7
| apo-ADGRG2 coupled to Gs | 分子名称: | Adhesion G-protein coupled receptor G2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Liu, Z.M, Bu, R.Q, Xue, C.Y, Guo, S.C, Yuan, D.P, Xiao, P, Sun, J.P. | 登録日 | 2022-08-02 | 公開日 | 2022-08-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | apo-ADGRG2 coupled to Gs Nat.Chem.Biol., 2022
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7YU3
| Human Lysophosphatidic Acid Receptor 1-Gi complex bound to ONO-0740556 | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Akasaka, H, Shihoya, W, Nureki, O. | 登録日 | 2022-08-16 | 公開日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure of the active G i -coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist. Nat Commun, 13, 2022
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7YU8
| Human Lysophosphatidic Acid Receptor 1-Gi complex bound to ONO-0740556, state4 | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Akasaka, H, Shihoya, W, Nureki, O. | 登録日 | 2022-08-16 | 公開日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structure of the active G i -coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist. Nat Commun, 13, 2022
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7YU5
| Human Lysophosphatidic Acid Receptor 1-Gi complex bound to ONO-0740556, state1 | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Akasaka, H, Shihoya, W, Nureki, O. | 登録日 | 2022-08-16 | 公開日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure of the active G i -coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist. Nat Commun, 13, 2022
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7YU7
| Human Lysophosphatidic Acid Receptor 1-Gi complex bound to ONO-0740556, state3 | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Akasaka, H, Shihoya, W, Nureki, O. | 登録日 | 2022-08-16 | 公開日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure of the active G i -coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist. Nat Commun, 13, 2022
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7YU6
| Human Lysophosphatidic Acid Receptor 1-Gi complex bound to ONO-0740556, state2 | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Akasaka, H, Shihoya, W, Nureki, O. | 登録日 | 2022-08-16 | 公開日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure of the active G i -coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist. Nat Commun, 13, 2022
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7YON
| Complex structure of Neuropeptide Y Y2 receptor in complex with PYY(3-36) and Gi | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Kang, H, Park, C, Kim, J, Choi, H.-J. | 登録日 | 2022-08-01 | 公開日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Structural basis for Y2 receptor-mediated neuropeptide Y and peptide YY signaling. Structure, 31, 2023
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7YOO
| Complex structure of Neuropeptide Y Y2 receptor in complex with NPY and Gi | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Kang, H, Park, C, Kim, J, Choi, H.-J. | 登録日 | 2022-08-01 | 公開日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | 主引用文献 | Structural basis for Y2 receptor-mediated neuropeptide Y and peptide YY signaling. Structure, 31, 2023
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8UNP
| CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class E) | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | 登録日 | 2023-10-19 | 公開日 | 2024-03-06 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 2024
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8UNW
| CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class L) | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | 登録日 | 2023-10-19 | 公開日 | 2024-03-06 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
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8UO1
| CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class Q) | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | 登録日 | 2023-10-19 | 公開日 | 2024-03-06 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 2024
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8UNY
| CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class N) | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | 登録日 | 2023-10-19 | 公開日 | 2024-03-06 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
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8UNM
| CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class B) | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | 登録日 | 2023-10-19 | 公開日 | 2024-03-06 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 2024
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