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8X63	CryoEM structure of the histamine H1 receptor-BRIL/Anti BRIL Fab complex with mepyramine Descriptor: Histamine H1 receptor,Soluble cytochrome b562, mepyramine Authors: Wang, D.D, Guo, Q. Deposit date: 2023-11-20 Release date: 2024-01-17 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Molecular mechanism of antihistamines recognition and regulation of the histamine H 1 receptor. Nat Commun, 15, 2024
8X64	CryoEM structure of the histamine H1 receptor-BRIL/Anti BRIL Fab complex with desloratadine Descriptor: Histamine H1 receptor,Soluble cytochrome b562, desloratadine Authors: Wang, D.D, Guo, Q. Deposit date: 2023-11-20 Release date: 2024-01-17 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Molecular mechanism of antihistamines recognition and regulation of the histamine H 1 receptor. Nat Commun, 15, 2024
6XPQ	Human antibody D1 H1-17/H3-14 in complex with the influenza hemagglutinin head domain of A/Texas/50/2012(H3N2) Descriptor: Hemagglutinin, antibody D1 H1-17/H3-14 light chain, antibody D1 H1-17/H3-14 heavy chain, ... Authors: McCarthy, K.R, Harrison, S.C. Deposit date: 2020-07-08 Release date: 2021-05-19 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (4.2 Å) Cite: A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface. Mbio, 12, 2021
6XPR	Human antibody D2 H1-1/H3-1 H3 in complex with the influenza hemagglutinin head domain of A/Texas/50/2012(H3N2) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: McCarthy, K.R, Harrison, S.C, Lee, J. Deposit date: 2020-07-08 Release date: 2021-05-19 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (4.092 Å) Cite: A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface. Mbio, 12, 2021
7T3D	CryoEM map of anchor 222-1C06 Fab and lateral patch 2B05 Fab binding H1 HA Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 222-1C06 mAb heavy chain, ... Authors: Han, J, Ward, A.B. Deposit date: 2021-12-07 Release date: 2022-01-12 Last modified: 2022-03-30 Method: ELECTRON MICROSCOPY (3.38 Å) Cite: Broadly neutralizing antibodies target a haemagglutinin anchor epitope. Nature, 602, 2022
6HQ1	Solution structure of the globular domain from human histone H1.0 Descriptor: Histone H1.0 Authors: Martinsen, J.H, Bugge, K, Kragelund, B.B. Deposit date: 2018-09-23 Release date: 2019-10-09 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Micromolar affinity association of an IDP and a folded protein without the involvement of persistent binding sites To Be Published
2WRG	structure of H1 1918 hemagglutinin with human receptor Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ HA1 CHAIN, HEMAGGLUTININ HA2 CHAIN, ... Authors: Liu, J, Stevens, D.J, Haire, L.F, Walker, P.A, Coombs, P.J, Russell, R.J, Gamblin, S.J, Skehel, J.J. Deposit date: 2009-09-01 Release date: 2009-09-29 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (3 Å) Cite: From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957. Proc.Natl.Acad.Sci.USA, 106, 2009
7MFG	Cryo-EM structure of the VRC310 clinical trial, vaccine-elicited, human antibody 310-030-1D06 Fab in complex with an H1 NC99 HA trimer Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 310-030-1D06 Heavy, 310-030-1D06 Light, ... Authors: Gorman, J, Kwong, P.D. Deposit date: 2021-04-09 Release date: 2021-11-03 Last modified: 2022-03-09 Method: ELECTRON MICROSCOPY (3.87 Å) Cite: A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination. Nat Med, 28, 2022
6A52	Oxidase ChaP-H1 Descriptor: FE (II) ION, dioxidase ChaP-H1 Authors: Zhang, B, Ge, H.M. Deposit date: 2018-06-21 Release date: 2018-08-29 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (2 Å) Cite: Molecular Basis for the Final Oxidative Rearrangement Steps in Chartreusin Biosynthesis. J. Am. Chem. Soc., 140, 2018
4RSY	Crystal structures of the Human leukotriene A4 Hydrolase complex with a potential inhibitor H7 Descriptor: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, ACETIC ACID, IMIDAZOLE, ... Authors: Ouyang, P, Lu, W, Cui, K, Huang, J. Deposit date: 2014-11-12 Release date: 2015-12-02 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Structure of Human Leukotriene A4 Hydrolase in complex with inhibitor H1 To be Published
3F81	Interaction of VHR with SA3 Descriptor: 2-[(5~{E})-5-[[3-[4-(2-fluoranylphenoxy)phenyl]-1-phenyl-pyrazol-4-yl]methylidene]-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-3-yl]ethanesulfonic acid, Dual specificity protein phosphatase 3 Authors: Wu, S, Mutelin, T, Tautz, L. Deposit date: 2008-11-11 Release date: 2009-11-10 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Multidentate small-molecule inhibitors of vaccinia H1-related (VHR) phosphatase decrease proliferation of cervix cancer cells. J.Med.Chem., 52, 2009
3DM1	Crystal structure of the complex of human chromobox homolog 3 (CBX3) with peptide Descriptor: Chromobox protein homolog 3, Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Authors: Amaya, M.F, Ravichandran, M, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC) Deposit date: 2008-06-30 Release date: 2008-08-19 Last modified: 2017-10-25 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural basis of the chromodomain of Cbx3 bound to methylated peptides from histone h1 and G9a. Plos One, 7, 2012
2RHI	Crystal structure of the 3-MBT domain from human L3MBTL1 in complex with H1.5K27me2 at 1.66 angstrom Descriptor: DI(HYDROXYETHYL)ETHER, Histone H1.5, Lethal(3)malignant brain tumor-like protein, ... Authors: Li, H, Patel, D.J. Deposit date: 2007-10-09 Release date: 2007-12-11 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.66 Å) Cite: Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger. Mol.Cell, 28, 2007
2WRH	structure of H1 duck albert hemagglutinin with human receptor Descriptor: HEMAGGLUTININ HA1 CHAIN, HEMAGGLUTININ HA2 CHAIN, N-acetyl-alpha-neuraminic acid Authors: Liu, J, Stevens, D.J, Haire, L.F, Walker, P.A, Coombs, P.J, Russell, R.J, Gamblin, S.J, Skehel, J.J. Deposit date: 2009-09-01 Release date: 2009-09-29 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (3 Å) Cite: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957 Proc.Natl.Acad.Sci.USA, 106, 2009
4ALO	STRUCTURE AND PROPERTIES OF H1 CRUSTACYANIN FROM LOBSTER HOMARUS AMERICANUS Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, H1 APOCRUSTACYANIN, SODIUM ION, ... Authors: Ferrari, M, Folli, C, Pincolini, E, Mcclintock, T.S, Roessle, M, Berni, R, Cianci, M. Deposit date: 2012-03-05 Release date: 2012-08-08 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.37 Å) Cite: Structural Characterization of Recombinant Crustacyanin Subunits from the Lobster Homarus Americanus. Acta Crystallogr.,Sect.F, 68, 2012
6DOB	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mg2+ and 200 mM K+ for 200 s at 21 C Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*AP*TP*GP*T)-3'), GLYCEROL, ... Authors: Samara, N.L, Yang, W. Deposit date: 2018-06-09 Release date: 2018-08-15 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.343 Å) Cite: Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
6DOL	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mg2+ and 25 mM K+ for 120 s at 21 C (dataset 2) Descriptor: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of intact RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), 5'-R(P*CP*G)-3' portion of intact RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), ... Authors: Samara, N.L, Yang, W. Deposit date: 2018-06-09 Release date: 2018-08-15 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.433 Å) Cite: Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
6DOZ	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 1 mM Mg2+ and 75 mM K+ for 40 s at 21 C Descriptor: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of uncleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', 5'-R(P*CP*G)-3' portion of uncleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', ... Authors: Samara, N.L, Yang, W. Deposit date: 2018-06-09 Release date: 2018-08-15 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.573 Å) Cite: Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
6DPE	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 20 mM Mn2+ and 200 mM K+ for 40 s at 21 C Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*AP*TP*GP*T)-3'), GLYCEROL, ... Authors: Samara, N.L, Yang, W. Deposit date: 2018-06-09 Release date: 2018-08-15 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.56 Å) Cite: Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
6DOM	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mg2+ and 50 mM K+ for 120 s at 21 C Descriptor: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of cleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', 5'-R(P*CP*G)-3' portion of cleaved RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), ... Authors: Samara, N.L, Yang, W. Deposit date: 2018-06-09 Release date: 2018-08-15 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.425 Å) Cite: Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
6DP2	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 7.5 mM Mg2+ and 75 mM K+ for 40 s at 21 C Descriptor: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of uncleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', 5'-R(P*CP*G)-3' portion of uncleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', ... Authors: Samara, N.L, Yang, W. Deposit date: 2018-06-09 Release date: 2018-08-15 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.662 Å) Cite: Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
6DPO	Crystal Structure of Bacillus Halodurans Ribonuclease H1 E188A in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mg2+ and 200 mM K+ for 360 s at 21 C Descriptor: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of cleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', 5'-R(P*CP*G)-3' portion of cleaved RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), ... Authors: Samara, N.L, Yang, W. Deposit date: 2018-06-09 Release date: 2018-08-15 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
6DMN	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Soaked in 2 mM Ca2+ and 200 mM K+ at 21 C Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, DNA (5'-D(*CP*GP*AP*TP*GP*T)-3'), ... Authors: Samara, N.L, Yang, W. Deposit date: 2018-06-05 Release date: 2018-08-15 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.27 Å) Cite: Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
6DOW	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 5 mM Mg2+ and 200 mM Rb+ for 160 s at 21 C Descriptor: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of cleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', 5'-R(P*CP*G)-3' portion of cleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', ... Authors: Samara, N.L, Yang, W. Deposit date: 2018-06-09 Release date: 2018-08-15 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.495 Å) Cite: Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
6DP9	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mn2+ and 200 mM K+ for 40 s at 21 C Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*AP*TP*GP*T)-3'), GLYCEROL, ... Authors: Samara, N.L, Yang, W. Deposit date: 2018-06-09 Release date: 2018-08-15 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018

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