2RHI
Crystal structure of the 3-MBT domain from human L3MBTL1 in complex with H1.5K27me2 at 1.66 angstrom
Summary for 2RHI
Entry DOI | 10.2210/pdb2rhi/pdb |
Related | 2RHU 2RHX 2RHY 2RHZ 2RI2 2RI3 2RI5 |
Descriptor | Lethal(3)malignant brain tumor-like protein, Histone H1.5, TETRAETHYLENE GLYCOL, ... (5 entities in total) |
Functional Keywords | beta barrel, protein-peptide complex, dimethyl-lysine, alternative splicing, chromatin regulator, dna-binding, metal-binding, nucleus, repressor, transcription, transcription regulation, zinc, zinc-finger, transcription-nuclear protein complex, transcription/nuclear protein |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q9Y468 P16401 |
Total number of polymer chains | 2 |
Total formula weight | 40100.86 |
Authors | Li, H.,Patel, D.J. (deposition date: 2007-10-09, release date: 2007-12-11, Last modification date: 2023-08-30) |
Primary citation | Li, H.,Fischle, W.,Wang, W.,Duncan, E.M.,Liang, L.,Murakami-Ishibe, S.,Allis, C.D.,Patel, D.J. Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger. Mol.Cell, 28:677-691, 2007 Cited by PubMed: 18042461DOI: 10.1016/j.molcel.2007.10.023 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.66 Å) |
Structure validation
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