2PX9
 
 | | The intrinsic affinity between E2 and the Cys domain of E1 in Ubiquitin-like modifications | | Descriptor: | SUMO-activating enzyme subunit 2, SUMO-conjugating enzyme UBC9 | | Authors: | Wang, J.H, Hu, W.D, Cai, S, Lee, B, Song, J, Chen, Y. | | Deposit date: | 2007-05-14 | | Release date: | 2007-07-24 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The intrinsic affinity between E2 and the Cys domain of E1 in ubiquitin-like modifications.
Mol.Cell, 27, 2007
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2PWQ
 | | Crystal structure of a putative ubiquitin conjugating enzyme from Plasmodium yoelii | | Descriptor: | Ubiquitin conjugating enzyme | | Authors: | Qiu, W, Dong, A, Hassanali, A, Lin, L, Brokx, S, Altamentova, S, Hills, T, Lew, J, Ravichandran, M, Kozieradzki, I, Zhao, Y, Schapira, M, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Structural Genomics Consortium (SGC) | | Deposit date: | 2007-05-11 | | Release date: | 2007-05-22 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of a putative ubiquitin conjugating enzyme from Plasmodium yoelii.
To be Published
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2OXQ
 | | Structure of the UbcH5 :CHIP U-box complex | | Descriptor: | CHLORIDE ION, STIP1 homology and U-Box containing protein 1, Ubiquitin-conjugating enzyme E2D 1 | | Authors: | Xu, Z, Nix, J.C, Devlin, K.I, Misra, S. | | Deposit date: | 2007-02-20 | | Release date: | 2008-02-19 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Interactions between the quality control ubiquitin ligase CHIP and ubiquitin conjugating enzymes.
Bmc Struct.Biol., 8, 2008
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2LXP
 | | NMR structure of two domains in ubiquitin ligase gp78, RING and G2BR, bound to its conjugating enzyme Ube2g | | Descriptor: | E3 ubiquitin-protein ligase AMFR, Ubiquitin-conjugating enzyme E2 G2, ZINC ION | | Authors: | Das, R, Linag, Y, Mariano, J, Li, J, Huang, T, King, A, Weissman, A, Ji, X, Byrd, R. | | Deposit date: | 2012-08-30 | | Release date: | 2013-08-28 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine.
Embo J., 32, 2013
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6ZHT
 | | Uba1-Ubc13 disulfide mediated complex | | Descriptor: | CHLORIDE ION, GLYCEROL, Ubiquitin-activating enzyme E1 1, ... | | Authors: | Schaefer, A, Misra, M, Schindelin, H. | | Deposit date: | 2020-06-23 | | Release date: | 2022-01-12 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | ATP induced conformational changes facilitate E1-E2 disulfide bridging in the ubiquitin system.
To Be Published
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6ZHS
 | | Uba1 bound to two E2 (Ubc13) molecules | | Descriptor: | GLYCEROL, SULFATE ION, Ubiquitin-activating enzyme E1 1, ... | | Authors: | Misra, M, Schindelin, H. | | Deposit date: | 2020-06-23 | | Release date: | 2022-01-12 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | ATP induced conformational changes facilitate E1-E2 disulfide bridging in the ubiquitin system.
To Be Published
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6ZHU
 | | Yeast Uba1 in complex with Ubc3 and ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ubiquitin-activating enzyme E1 1, ... | | Authors: | Misra, M, Schindelin, H. | | Deposit date: | 2020-06-23 | | Release date: | 2022-01-12 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.18 Å) | | Cite: | ATP induced conformational changes facilitate E1-E2 disulfide bridging in the ubiquitin system
To Be Published
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7AI0
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7AHZ
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7AI1
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7BXG
 | | MavC-UBE2N-Ub complex | | Descriptor: | MavC, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N | | Authors: | Gao, P, Wang, Y. | | Deposit date: | 2020-04-19 | | Release date: | 2020-05-20 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.705 Å) | | Cite: | Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors.
Nat Commun, 11, 2020
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7BBF
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2BF8
 | | Crystal structure of SUMO modified ubiquitin conjugating enzyme E2- 25K | | Descriptor: | UBIQUITIN-CONJUGATING ENZYME E2-25 KDA, UBIQUITIN-LIKE PROTEIN SMT3C | | Authors: | Pichler, A, Knipscheer, P, Oberhofer, E, Van Dijk, W.J, Korner, R, Velgaard Olsen, J, Jentsch, S, Melchior, F, Sixma, T.K. | | Deposit date: | 2004-12-06 | | Release date: | 2005-02-16 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Sumo Imodification of the Ubiquitin Conjugating Enzyme E2-25K
Nat.Struct.Mol.Biol., 12, 2005
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2C2V
 | | Crystal structure of the CHIP-UBC13-UEV1a complex | | Descriptor: | STIP1 homology and U box-containing protein 1, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 1 | | Authors: | Zhang, M, Roe, S.M, Pearl, L.H. | | Deposit date: | 2005-09-30 | | Release date: | 2005-11-23 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex.
Mol. Cell, 20, 2005
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2EKE
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1YLA
 | | Ubiquitin-conjugating enzyme E2-25 kDa (Huntington interacting protein 2) | | Descriptor: | Ubiquitin-conjugating enzyme E2-25 kDa | | Authors: | Choe, J, Avvakumov, G.V, Newman, E.M, Mackenzie, F, Kozieradzki, I, Bochkarev, A, Sundstrom, M, Arrowsmith, C, Edwards, A, Dhe-paganon, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2005-01-19 | | Release date: | 2005-02-01 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity
J.Biol.Chem., 285, 2010
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1ZGU
 | | Solution structure of the human Mms2-Ubiquitin complex | | Descriptor: | Ubiquitin, Ubiquitin-conjugating enzyme E2 variant 2 | | Authors: | Lewis, M.J, Saltibus, L.F, Hau, D.D, Xiao, W, Spyracopoulos, L. | | Deposit date: | 2005-04-22 | | Release date: | 2006-04-04 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structural Basis for Non-Covalent Interaction Between Ubiquitin and the Ubiquitin Conjugating Enzyme Variant Human MMS2.
J.Biomol.Nmr, 34, 2006
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1Z5S
 | | Crystal structure of a complex between UBC9, SUMO-1, RANGAP1 and NUP358/RANBP2 | | Descriptor: | Ran GTPase-activating protein 1, Ran-binding protein 2, Ubiquitin-conjugating enzyme E2 I, ... | | Authors: | Reverter, D, Lima, C.D. | | Deposit date: | 2005-03-19 | | Release date: | 2005-06-07 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.01 Å) | | Cite: | Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex.
Nature, 435, 2005
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1Y8X
 | | Structural basis for recruitment of Ubc12 by an E2-binding domain in NEDD8's E1 | | Descriptor: | Ubiquitin-activating enzyme E1C, Ubiquitin-conjugating enzyme E2 M | | Authors: | Huang, D.T, Paydar, A, Zhuang, M, Waddell, M.B, Holton, J.M, Schulman, B.A. | | Deposit date: | 2004-12-13 | | Release date: | 2005-02-08 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1.
Mol.Cell, 17, 2005
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8IVQ
 | | Cryo-EM structure of mouse BIRC6, Global map | | Descriptor: | Isoform 2 of Baculoviral IAP repeat-containing protein 6 | | Authors: | Liu, S, Jiang, T, Bu, F, Zhao, J, Wang, G, Li, N, Gao, N, Qiu, X. | | Deposit date: | 2023-03-28 | | Release date: | 2024-01-24 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Molecular mechanisms underlying the BIRC6-mediated regulation of apoptosis and autophagy.
Nat Commun, 15, 2024
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5D1L
 | | Crystal Structure of UbcH5B in Complex with the RING-U5BR Fragment of AO7 (Y165A) | | Descriptor: | DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase RNF25, OXALATE ION, ... | | Authors: | Liang, Y.-H, Li, S, Weissman, A.M, Ji, X. | | Deposit date: | 2015-08-04 | | Release date: | 2015-10-28 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.618 Å) | | Cite: | Insights into Ubiquitination from the Unique Clamp-like Binding of the RING E3 AO7 to the E2 UbcH5B.
J.Biol.Chem., 290, 2015
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5DFL
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8JWU
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8JWJ
 | | PHD Finger Protein 7 (PHF7) in complex with UBE2D2 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, PHD finger protein 7, ... | | Authors: | Lee, H.S, Bang, I, Choi, H.-J. | | Deposit date: | 2023-06-29 | | Release date: | 2023-12-20 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.96 Å) | | Cite: | Molecular basis for PHF7-mediated ubiquitination of histone H3.
Genes Dev., 37, 2023
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5D0K
 | | Structure of UbE2D2:RNF165:Ub complex | | Descriptor: | Polyubiquitin-B, RING finger protein 165, Ubiquitin-conjugating enzyme E2 D2, ... | | Authors: | Wright, J.D, Day, C.L, Mace, P.D. | | Deposit date: | 2015-08-03 | | Release date: | 2015-12-09 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity.
Nat.Struct.Mol.Biol., 23, 2016
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