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PDB: 65 results

5KK2
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BU of 5kk2 by Molmil
Architecture of fully occupied GluA2 AMPA receptor - TARP complex elucidated by single particle cryo-electron microscopy
Descriptor: Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Zhao, Y, Chen, S, Yoshioka, C, Baconguis, I, Gouaux, E.
Deposit date:2016-06-20
Release date:2016-07-06
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:Architecture of fully occupied GluA2 AMPA receptor-TARP complex elucidated by cryo-EM.
Nature, 536, 2016
6PZC
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BU of 6pzc by Molmil
Cryo-EM structure of the pancreatic beta-cell SUR1 bound to carbamazepine
Descriptor: ATP-binding cassette sub-family C member 8
Authors:Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W.
Deposit date:2019-07-31
Release date:2019-08-14
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.34 Å)
Cite:Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.
Elife, 8, 2019
6PZA
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BU of 6pza by Molmil
Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and glibenclamide
Descriptor: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
Authors:Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W.
Deposit date:2019-07-31
Release date:2019-08-14
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.
Elife, 8, 2019
1Z97
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BU of 1z97 by Molmil
Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer.
Descriptor: Carbonic anhydrase III, ZINC ION
Authors:Duda, D.M, Tu, C, Fisher, S.Z, An, H, Yoshioka, C, Govindasamy, L, Laipis, P.J, Agbandje-McKenna, M, Silverman, D.N, McKenna, R.
Deposit date:2005-03-31
Release date:2005-08-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer
Biochemistry, 44, 2005
1Z93
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BU of 1z93 by Molmil
Human Carbonic Anhydrase III:Structural and Kinetic study of Catalysis and Proton Transfer.
Descriptor: Carbonic anhydrase III, ZINC ION
Authors:Duda, D.M, Tu, C, Fisher, S.Z, An, H, Yoshioka, C, Govindasamy, L, Laipis, P.J, Agbandje-McKenna, M, Silverman, D.N, McKenna, R.
Deposit date:2005-03-31
Release date:2005-08-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer
Biochemistry, 44, 2005
6PZ9
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BU of 6pz9 by Molmil
Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and repaglinide
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11, ...
Authors:Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W.
Deposit date:2019-07-31
Release date:2019-08-14
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.
Elife, 8, 2019
1LZV
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BU of 1lzv by Molmil
Site-Specific Mutant (Tyr7 replaced with His) of Human Carbonic Anhydrase II
Descriptor: Carbonic Anhydrase II, ZINC ION
Authors:Tu, C.K, Qian, M, An, H, Wadhwa, N.R, Duda, D.M, Yoshioka, C, Pathak, Y, McKenna, R, Laipis, P.J, Silverman, D.N.
Deposit date:2002-06-11
Release date:2002-10-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Kinetic analysis of multiple proton shuttles in the active site of human carbonic anhydrase.
J.Biol.Chem., 277, 2002
5TWV
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BU of 5twv by Molmil
Cryo-EM structure of the pancreatic ATP-sensitive K+ channel SUR1/Kir6.2 in the presence of ATP and glibenclamide
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11
Authors:Martin, G.M, Yoshioka, C, Chen, J.Z, Shyng, S.L.
Deposit date:2016-11-14
Release date:2017-01-25
Last modified:2019-12-25
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating.
Elife, 6, 2017
6NZ0
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BU of 6nz0 by Molmil
Cryo-EM structure of AAV-2 in complex with AAVR PKD domains 1 and 2
Descriptor: Capsid protein VP1, Dyslexia-associated protein KIAA0319-like protein, MAGNESIUM ION
Authors:Meyer, N.L, Xie, Q, Davulcu, O, Yoshioka, C, Chapman, M.S.
Deposit date:2019-02-12
Release date:2019-06-12
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structure of the gene therapy vector, adeno-associated virus with its cell receptor, AAVR.
Elife, 8, 2019
7JMC
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BU of 7jmc by Molmil
Sheep Connexin-50 at 2.5 angstroms resolution, Lipid Class 3
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-8 protein
Authors:Flores, J.A, Haddad, B.G, Dolan, K.D, Myers, J.B, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L.
Deposit date:2020-07-31
Release date:2020-09-09
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom.
Nat Commun, 11, 2020
6PZB
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BU of 6pzb by Molmil
Cryo-EM structure of the pancreatic beta-cell SUR1 Apo state
Descriptor: ATP-binding cassette sub-family C member 8
Authors:Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W.
Deposit date:2019-07-31
Release date:2019-08-14
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (4.55 Å)
Cite:Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.
Elife, 8, 2019
6PZI
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BU of 6pzi by Molmil
Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP only
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8
Authors:Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W.
Deposit date:2019-07-31
Release date:2019-08-14
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.
Elife, 8, 2019
7JMD
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BU of 7jmd by Molmil
Sheep Connexin-46 at 2.5 angstroms resolution, Lipid Class 1
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-3 protein
Authors:Flores, J.A, Haddad, B.G, Dolan, K.A, Myers, J.B, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L.
Deposit date:2020-07-31
Release date:2020-09-09
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom.
Nat Commun, 11, 2020
7JM9
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BU of 7jm9 by Molmil
Sheep Connexin-50 at 2.5 angstroms reoslution, Lipid Class 2
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-8 protein
Authors:Flores, J.A, Haddad, B.G, Dolan, K.A, Myers, J.A, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L.
Deposit date:2020-07-31
Release date:2020-09-09
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom.
Nat Commun, 11, 2020
7JLW
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BU of 7jlw by Molmil
Sheep Connexin-50 at 2.5 angstroms resolution, Lipid Class 1
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-8 protein
Authors:Flores, J.A, Haddad, B.G, Dolan, K.A, Myers, J.B, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L.
Deposit date:2020-07-30
Release date:2020-09-09
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom.
Nat Commun, 11, 2020
7JN0
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BU of 7jn0 by Molmil
Sheep Connexin-46 at 2.5 angstroms resolution, Lipid Class 2
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-3 protein
Authors:Flores, J.A, Haddad, B.G, Dolan, K.A, Myers, J.A, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L.
Deposit date:2020-08-03
Release date:2020-09-09
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom.
Nat Commun, 11, 2020
7JJP
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BU of 7jjp by Molmil
Sheep Connexin-50 at 1.9 angstroms resolution by CryoEM
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-8 protein
Authors:Flores, J.A, Haddad, B.G, Dolan, K.D, Myers, J.B, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L.
Deposit date:2020-07-27
Release date:2020-09-09
Method:ELECTRON MICROSCOPY (1.94 Å)
Cite:Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom.
Nat Commun, 11, 2020
7JN1
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BU of 7jn1 by Molmil
Sheep Connexin-46 at 2.5 angstroms resolution, Lipid Class 3
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-3 protein
Authors:Flores, J.A, Haddad, B.G, Dolan, K.D, Myers, J.B, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L.
Deposit date:2020-08-03
Release date:2020-09-09
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom.
Nat Commun, 11, 2020
5IPT
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BU of 5ipt by Molmil
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 5
Descriptor: Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a
Authors:Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E.
Deposit date:2016-03-09
Release date:2016-04-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (14.1 Å)
Cite:Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5IOU
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BU of 5iou by Molmil
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the glutamate/glycine-bound conformation
Descriptor: GLUTAMIC ACID, GLYCINE, Ionotropic glutamate receptor subunit NR2B, ...
Authors:Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E.
Deposit date:2016-03-09
Release date:2016-04-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5IPU
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BU of 5ipu by Molmil
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 6
Descriptor: Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a
Authors:Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E.
Deposit date:2016-03-09
Release date:2016-04-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (15.4 Å)
Cite:Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5IPS
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BU of 5ips by Molmil
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 4
Descriptor: Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a
Authors:Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E.
Deposit date:2016-03-09
Release date:2016-04-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (13.5 Å)
Cite:Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5IOV
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BU of 5iov by Molmil
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the glutamate/glycine/Ro25-6981-bound conformation
Descriptor: 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol, GLUTAMIC ACID, GLYCINE, ...
Authors:Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E.
Deposit date:2016-03-09
Release date:2016-04-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5IPV
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BU of 5ipv by Molmil
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 1
Descriptor: Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a
Authors:Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, McHaourab, S.H, Gouaux, E.
Deposit date:2016-03-10
Release date:2016-04-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (9.25 Å)
Cite:Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5IPR
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BU of 5ipr by Molmil
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 3
Descriptor: Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a
Authors:Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E.
Deposit date:2016-03-09
Release date:2016-04-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (14.1 Å)
Cite:Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016

 

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