1LZV

Site-Specific Mutant (Tyr7 replaced with His) of Human Carbonic Anhydrase II

Summary for 1LZV

Entry DOI	10.2210/pdb1lzv/pdb
Descriptor	Carbonic Anhydrase II, ZINC ION (3 entities in total)
Functional Keywords	twisted beta sheet, zinc metalloenzyme, lyase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P00918
Total number of polymer chains	1
Total formula weight	29329.44
Authors	Tu, C.K.,Qian, M.,An, H.,Wadhwa, N.R.,Duda, D.M.,Yoshioka, C.,Pathak, Y.,McKenna, R.,Laipis, P.J.,Silverman, D.N. (deposition date: 2002-06-11, release date: 2002-10-23, Last modification date: 2024-02-14)
Primary citation	Tu, C.,Qian, M.,An, H.,Wadhwa, N.R.,Duda, D.,Yoshioka, C.,Pathak, Y.,McKenna, R.,Laipis, P.J.,Silverman, D.N. Kinetic analysis of multiple proton shuttles in the active site of human carbonic anhydrase. J.Biol.Chem., 277:38870-38876, 2002 Cited by PubMed: 12171926 DOI: 10.1074/jbc.M205791200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation