4IJF
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![BU of 4ijf by Molmil](/molmil-images/mine/4ijf) | Crystal structure of the Zaire ebolavirus VP35 interferon inhibitory domain K222A/R225A/K248A/K251A mutant | Descriptor: | Polymerase cofactor VP35 | Authors: | Binning, J.B, Wang, T, Leung, D.W, Xu, W, Borek, D, Amarasinghe, G.K. | Deposit date: | 2012-12-21 | Release date: | 2013-10-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.506 Å) | Cite: | Development of RNA Aptamers Targeting Ebola Virus VP35. Biochemistry, 52, 2013
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4IBK
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![BU of 4ibk by Molmil](/molmil-images/mine/4ibk) | Ebola virus VP35 bound to small molecule | Descriptor: | 3-{(2S)-2-(7-chloro-1,3-benzodioxol-5-yl)-3-[(5-chlorothiophen-2-yl)carbonyl]-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl}benzoic acid, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Brown, C.S, Leung, D.W, Xu, W, Borek, D.M, Otwinowski, Z, Ramanan, P, Stubbs, A.J, Peterson, D.S, Binning, J.M, Amarasinghe, G.K. | Deposit date: | 2012-12-08 | Release date: | 2014-03-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | In Silico Derived Small Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor Activity. J.Mol.Biol., 426, 2014
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4IJE
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![BU of 4ije by Molmil](/molmil-images/mine/4ije) | Crystal structure of the Zaire ebolavirus VP35 interferon inhibitory domain R312A/K319A/R322A mutant | Descriptor: | PHOSPHATE ION, POTASSIUM ION, Polymerase cofactor VP35, ... | Authors: | Binning, J.B, Wang, T, Leung, D.W, Xu, W, Borek, D, Amarasinghe, G.K. | Deposit date: | 2012-12-21 | Release date: | 2013-10-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.899 Å) | Cite: | Development of RNA Aptamers Targeting Ebola Virus VP35. Biochemistry, 52, 2013
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4IBC
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![BU of 4ibc by Molmil](/molmil-images/mine/4ibc) | Ebola virus VP35 bound to small molecule | Descriptor: | DIMETHYL SULFOXIDE, Polymerase cofactor VP35, {4-[(2R)-3-(2-chlorobenzoyl)-2-(2-chlorophenyl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl]phenyl}acetic acid | Authors: | Brown, C.S, Leung, D.W, Xu, W, Borek, D.M, Otwinowski, Z, Ramanan, P, Stubbs, A.J, Peterson, D.S, Binning, J.M, Amarasinghe, G.K. | Deposit date: | 2012-12-08 | Release date: | 2014-03-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.745 Å) | Cite: | In Silico Derived Small Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor Activity. J.Mol.Biol., 426, 2014
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7MSY
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![BU of 7msy by Molmil](/molmil-images/mine/7msy) | Structure of CalU17 from the Calicheamicin Biosynthesis Pathway of Micromonospora echinospora | Descriptor: | CALCIUM ION, CHLORIDE ION, CalU17, ... | Authors: | Kosgei, A.J, Miller, M.D, Xu, W, Van Lanen, S.G, Thorson, J.S, Phillips Jr, G.N. | Deposit date: | 2021-05-12 | Release date: | 2021-07-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | The crystal structure of DynF from the dynemicin-biosynthesis pathway of Micromonospora chersina. Acta Crystallogr.,Sect.F, 78, 2022
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5WZZ
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![BU of 5wzz by Molmil](/molmil-images/mine/5wzz) | The SIAH E3 ubiquitin ligases promote Wnt/ beta-catenin signaling through mediating Wnt-induced Axin degradation | Descriptor: | Axin-1, E3 ubiquitin-protein ligase SIAH1, ZINC ION | Authors: | Ji, L, Jiang, B, Jiang, X, Charlat, O, Chen, A, Mickanin, C, Bauer, A, Xu, W, Yan, X.-X, Cong, F. | Deposit date: | 2017-01-19 | Release date: | 2017-08-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.103 Å) | Cite: | The SIAH E3 ubiquitin ligases promote Wnt/ beta-catenin signaling through mediating Wnt-induced Axin degradation Genes Dev., 31, 2017
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7DRT
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![BU of 7drt by Molmil](/molmil-images/mine/7drt) | Human Wntless in complex with Wnt3a | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhong, Q, Zhao, Y, Ye, F, Xiao, Z, Huang, G, Zhang, Y, Lu, P, Xu, W, Zhou, Q, Ma, D. | Deposit date: | 2020-12-29 | Release date: | 2021-07-14 | Last modified: | 2021-09-08 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Cryo-EM structure of human Wntless in complex with Wnt3a. Nat Commun, 12, 2021
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4XAU
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![BU of 4xau by Molmil](/molmil-images/mine/4xau) | Crystal structure of AtS13 from Actinomadura melliaura | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, Putative aminotransferase | Authors: | Wang, F, Singh, S, Xu, W, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2014-12-15 | Release date: | 2014-12-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.0012 Å) | Cite: | Structural characterization of AtmS13, a putative sugar aminotransferase involved in indolocarbazole AT2433 aminopentose biosynthesis. Proteins, 83, 2015
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6KHX
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![BU of 6khx by Molmil](/molmil-images/mine/6khx) | Crystal structure of Prx from Akkermansia muciniphila | Descriptor: | CALCIUM ION, Peroxiredoxin | Authors: | Li, M, Wang, J, Xu, W, Wang, Y, Zhang, M, Wang, M. | Deposit date: | 2019-07-16 | Release date: | 2020-02-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Crystal structure of Akkermansia muciniphila peroxiredoxin reveals a novel regulatory mechanism of typical 2-Cys Prxs by a distinct loop. Febs Lett., 594, 2020
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6LND
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![BU of 6lnd by Molmil](/molmil-images/mine/6lnd) | Crystal structure of transposition protein TniQ | Descriptor: | ZINC ION, transposition protein TniQ | Authors: | Wang, B, Xu, W, Yang, H. | Deposit date: | 2019-12-28 | Release date: | 2020-02-19 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Structural basis of a Tn7-like transposase recruitment and DNA loading to CRISPR-Cas surveillance complex. Cell Res., 30, 2020
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6LNB
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![BU of 6lnb by Molmil](/molmil-images/mine/6lnb) | CryoEM structure of Cascade-TniQ-dsDNA complex | Descriptor: | CRISPR RNA (60-MER), CRISPR-associated protein Cas6, CRISPR-associated protein Cas7, ... | Authors: | Wang, B, Xu, W, Yang, H. | Deposit date: | 2019-12-28 | Release date: | 2020-02-19 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | Structural basis of a Tn7-like transposase recruitment and DNA loading to CRISPR-Cas surveillance complex. Cell Res., 30, 2020
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6LNC
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![BU of 6lnc by Molmil](/molmil-images/mine/6lnc) | CryoEM structure of Cascade-TniQ complex | Descriptor: | CRISPR RNA (60-MER), CRISPR-associated protein Cas6, CRISPR-associated protein Cas7, ... | Authors: | Wang, B, Xu, W, Yang, H. | Deposit date: | 2019-12-28 | Release date: | 2020-02-19 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | Structural basis of a Tn7-like transposase recruitment and DNA loading to CRISPR-Cas surveillance complex. Cell Res., 30, 2020
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7UX8
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![BU of 7ux8 by Molmil](/molmil-images/mine/7ux8) | Crystal structure of MfnG, an L- and D-tyrosine O-methyltransferase from the marformycin biosynthesis pathway of Streptomyces drozdowiczii, with SAH and L-Tyrosine bound at 1.4 A resolution (P212121 - form II) | Descriptor: | MfnG, S-ADENOSYL-L-HOMOCYSTEINE, TYROSINE, ... | Authors: | Miller, M.D, Wu, K.-L, Xu, W, Xiao, H, Philips Jr, G.N. | Deposit date: | 2022-05-05 | Release date: | 2022-09-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Expanding the eukaryotic genetic code with a biosynthesized 21st amino acid. Protein Sci., 31, 2022
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7UX7
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![BU of 7ux7 by Molmil](/molmil-images/mine/7ux7) | Crystal structure of MfnG, an L- and D-tyrosine O-methyltransferase from the marformycin biosynthesis pathway of Streptomyces drozdowiczii, with SAH bound at 1.2 A resolution (P212121 - form II) | Descriptor: | MfnG, S-ADENOSYL-L-HOMOCYSTEINE, UNKNOWN LIGAND | Authors: | Miller, M.D, Wu, K.-L, Xu, W, Xiao, H, Philips Jr, G.N. | Deposit date: | 2022-05-05 | Release date: | 2022-10-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.14 Å) | Cite: | Expanding the eukaryotic genetic code with a biosynthesized 21st amino acid. Protein Sci., 31, 2022
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7UX6
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![BU of 7ux6 by Molmil](/molmil-images/mine/7ux6) | Crystal structure of MfnG, an L- and D-tyrosine O-methyltransferase from the marformycin biosynthesis pathway of Streptomyces drozdowiczii, with SAH bound at 1.35 A resolution (P212121 - form I) | Descriptor: | MfnG, S-ADENOSYL-L-HOMOCYSTEINE, UNKNOWN LIGAND | Authors: | Miller, M.D, Wu, K.-L, Xu, W, Xiao, H, Philips Jr, G.N. | Deposit date: | 2022-05-05 | Release date: | 2022-10-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Expanding the eukaryotic genetic code with a biosynthesized 21st amino acid. Protein Sci., 31, 2022
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7VUX
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![BU of 7vux by Molmil](/molmil-images/mine/7vux) | Complex structure of PD1 and 609A-Fab | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Huang, H, Zhu, Z, Zhao, J, Jiang, L, Yang, H, Deng, L, Meng, X, Ding, J, Yang, S, Zhao, L, Xu, W, Wang, X. | Deposit date: | 2021-11-04 | Release date: | 2021-11-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | A strategy for the efficient construction of anti-PD1-based bispecific antibodies with desired IgG-like properties. Mabs, 14, 2022
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2NV5
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![BU of 2nv5 by Molmil](/molmil-images/mine/2nv5) | Crystal structure of a C-terminal phosphatase domain of Rattus norvegicus ortholog of human protein tyrosine phosphatase, receptor type, D (PTPRD) | Descriptor: | PTPRD, PHOSPHATASE | Authors: | Bonanno, J.B, Gilmore, J, Bain, K.T, Iizuka, M, Xu, W, Wasserman, S, Smith, D, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2006-11-10 | Release date: | 2006-11-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural genomics of protein phosphatases. J.STRUCT.FUNCT.GENOM., 8, 2007
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2P8E
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![BU of 2p8e by Molmil](/molmil-images/mine/2p8e) | Crystal structure of the serine/threonine phosphatase domain of human PPM1B | Descriptor: | MAGNESIUM ION, PPM1B beta isoform variant 6 | Authors: | Bonanno, J.B, Freeman, J, Bain, K.T, Lau, C, Xu, W, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-03-22 | Release date: | 2007-04-03 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.816 Å) | Cite: | Structural genomics of protein phosphatases. J.Struct.Funct.Genom., 8, 2007
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2P4U
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![BU of 2p4u by Molmil](/molmil-images/mine/2p4u) | Crystal structure of acid phosphatase 1 (Acp1) from Mus musculus | Descriptor: | Acid phosphatase 1, PHOSPHATE ION | Authors: | Bonanno, J.B, Freeman, J, Bain, K.T, Wu, B, Xu, W, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-03-13 | Release date: | 2007-03-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural genomics of protein phosphatases. J.Struct.Funct.Genom., 8, 2007
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6DRU
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![BU of 6dru by Molmil](/molmil-images/mine/6dru) | Xylosidase from Aspergillus niger | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Glycosyl hydrolases family 31 family protein, ... | Authors: | Cao, H, Xu, W, Betancourt, M, Walton, J.D, Brumm, P, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2018-06-13 | Release date: | 2018-08-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structure of alpha-Xylosidase fromAspergillus nigerin Complex with a Hydrolyzed Xyloglucan Product and New Insights in Accurately Predicting Substrate Specificities of GH31 Family Glycosidases. Acs Sustain Chem Eng, 8, 2020
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