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PDB: 10 results

8I2C
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BU of 8i2c by Molmil
E. coli tryptophanyl-tRNA synthetase bound with a chemical fragment at the dimerization interface
Descriptor: 1,2-ETHANEDIOL, 4-methoxyaniline, SULFATE ION, ...
Authors:Xiang, M, Zhou, H.
Deposit date:2023-01-14
Release date:2023-04-12
Last modified:2023-06-07
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening.
Nucleic Acids Res., 51, 2023
8I1Z
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BU of 8i1z by Molmil
E. coli tryptophanyl-tRNA synthetase bound with a chemical fragment
Descriptor: 1-(2,3-dihydro-1-benzofuran-5-yl)ethanone, SULFATE ION, TRYPTOPHANYL-5'AMP, ...
Authors:Xiang, M, Zhou, H.
Deposit date:2023-01-13
Release date:2023-04-12
Last modified:2023-06-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening.
Nucleic Acids Res., 51, 2023
8I27
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BU of 8i27 by Molmil
E. coli tryptophanyl-tRNA synthetase bound with a chemical fragment at the dimerization interface
Descriptor: 1,2-ETHANEDIOL, 4-methoxybenzenecarbonitrile, SULFATE ION, ...
Authors:Xiang, M, Zhou, H.
Deposit date:2023-01-14
Release date:2023-04-12
Last modified:2023-06-07
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening.
Nucleic Acids Res., 51, 2023
8I2M
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BU of 8i2m by Molmil
The crystal structure of homodimeric E. coli tryptophanyl-tRNA synthetase bound with niraparib at one of its two active sites
Descriptor: 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide, SULFATE ION, TRYPTOPHANYL-5'AMP, ...
Authors:Xiang, M, Zhou, H.
Deposit date:2023-01-14
Release date:2023-04-12
Last modified:2023-06-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening.
Nucleic Acids Res., 51, 2023
8I2J
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BU of 8i2j by Molmil
E. coli tryptophanyl-tRNA synthetase bound with a chemical fragment at the dimerization interface
Descriptor: 1-(4-methoxyphenyl)ethanone, SULFATE ION, TRYPTOPHANYL-5'AMP, ...
Authors:Xiang, M, Zhou, H.
Deposit date:2023-01-14
Release date:2023-04-12
Last modified:2023-06-07
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening.
Nucleic Acids Res., 51, 2023
8I2A
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BU of 8i2a by Molmil
E. coli tryptophanyl-tRNA synthetase bound with a chemical fragment at the dimerization interface
Descriptor: 1,2-ETHANEDIOL, 5-METHOXYBENZIMIDAZOLE, SULFATE ION, ...
Authors:Xiang, M, Zhou, H.
Deposit date:2023-01-14
Release date:2023-04-12
Last modified:2023-06-07
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening.
Nucleic Acids Res., 51, 2023
8I4I
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BU of 8i4i by Molmil
The asymmetric structure of homodimeric E. coli TrpRS bound with tryptophanyl adenylate and L-tryptophan
Descriptor: SULFATE ION, TRYPTOPHAN, TRYPTOPHANYL-5'AMP, ...
Authors:Xiang, M, Zhou, H.
Deposit date:2023-01-19
Release date:2023-04-12
Last modified:2023-06-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening.
Nucleic Acids Res., 51, 2023
8I1W
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BU of 8i1w by Molmil
The asymmetric structure of homodimeric E. coli TrpRS bound with tryptophanyl adenylate at one of its two active pockets
Descriptor: SULFATE ION, TRYPTOPHANYL-5'AMP, Tryptophan--tRNA ligase
Authors:Xiang, M, Zhou, H.
Deposit date:2023-01-13
Release date:2023-04-12
Last modified:2023-06-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening.
Nucleic Acids Res., 51, 2023
8I1Y
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BU of 8i1y by Molmil
The structure of E. coli TrpRS bound with a chemical fragment
Descriptor: 5-ethanoylthiophene-2-carbonitrile, SULFATE ION, TRYPTOPHANYL-5'AMP, ...
Authors:Xiang, M, Zhou, H.
Deposit date:2023-01-13
Release date:2023-04-12
Last modified:2023-06-07
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening.
Nucleic Acids Res., 51, 2023
8I2L
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BU of 8i2l by Molmil
E. coli tryptophanyl-tRNA synthetase bound with a chemical fragment at the dimerization interface
Descriptor: 1,2-ETHANEDIOL, CHLORZOXAZONE, SULFATE ION, ...
Authors:Xiang, M, Zhou, H.
Deposit date:2023-01-14
Release date:2023-04-12
Last modified:2023-06-07
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening.
Nucleic Acids Res., 51, 2023

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