5Y4D
| Crystal Structure of AnkB Ankyrin Repeats in Complex with AnkR/AnkB Chimeric Autoinhibition Segment | Descriptor: | Ankyrin-1,Ankyrin-2,Ankyrin-2, SULFATE ION | Authors: | Chen, K, Li, J, Wang, C, Wei, Z, Zhang, M. | Deposit date: | 2017-08-03 | Release date: | 2017-09-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions. Elife, 6, 2017
|
|
5Y4F
| Crystal Structure of AnkB Ankyrin Repeats R13-24 in complex with autoinhibition segment AI-c | Descriptor: | ACETATE ION, Ankyrin-2, CALCIUM ION | Authors: | Chen, K, Li, J, Wang, C, Wei, Z, Zhang, M. | Deposit date: | 2017-08-03 | Release date: | 2017-09-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.953 Å) | Cite: | Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions. Elife, 6, 2017
|
|
6C1R
| Crystal structure of human C5a receptor in complex with an orthosteric antagonist PMX53 and an allosteric antagonist avacopan | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, MALONATE ION, OLEIC ACID, ... | Authors: | Liu, H, Wang, L, Wei, Z, Zhang, C. | Deposit date: | 2018-01-05 | Release date: | 2018-05-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Orthosteric and allosteric action of the C5a receptor antagonists. Nat. Struct. Mol. Biol., 25, 2018
|
|
6C1Q
| Crystal structure of human C5a receptor in complex with an orthosteric antagonist PMX53 and an allosteric antagonist NDT9513727 | Descriptor: | 1-(1,3-benzodioxol-5-yl)-~{N}-(1,3-benzodioxol-5-ylmethyl)-~{N}-[(3-butyl-2,5-diphenyl-imidazol-4-yl)methyl]methanamine, PMX53, Soluble cytochrome b562, ... | Authors: | Liu, H, Wang, L, Wei, Z, Zhang, C. | Deposit date: | 2018-01-05 | Release date: | 2018-05-30 | Last modified: | 2020-01-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Orthosteric and allosteric action of the C5a receptor antagonists. Nat. Struct. Mol. Biol., 25, 2018
|
|
7D2T
| Crystal structure of Rsu1/PINCH1_LIM45C complex | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, LIM and senescent cell antigen-like-containing domain protein 1, ... | Authors: | Yang, H, Wei, Z, Yu, C. | Deposit date: | 2020-09-17 | Release date: | 2021-02-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics. Elife, 10, 2021
|
|
7D2S
| Crystal structure of Rsu1/PINCH1_LIM5C complex | Descriptor: | GLYCEROL, LIM and senescent cell antigen-like-containing domain protein 1, Ras suppressor protein 1, ... | Authors: | Yang, H, Wei, Z, Cong, Y. | Deposit date: | 2020-09-17 | Release date: | 2021-02-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.653 Å) | Cite: | Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics. Elife, 10, 2021
|
|
7D2U
| Crystal structure of Rsu1/PINCH1_LIM45C complex | Descriptor: | GLYCEROL, LIM and senescent cell antigen-like-containing domain protein 1, MALONATE ION, ... | Authors: | Yang, H, Wei, Z, Cong, Y. | Deposit date: | 2020-09-17 | Release date: | 2021-02-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics. Elife, 10, 2021
|
|
7D2E
| Tetrameric coiled-coil structure of liprin-alpha2_H3 | Descriptor: | Liprin-alpha-2 | Authors: | Liang, M, Wei, Z. | Deposit date: | 2020-09-16 | Release date: | 2021-04-07 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Oligomerized liprin-alpha promotes phase separation of ELKS for compartmentalization of presynaptic active zone proteins. Cell Rep, 34, 2021
|
|
7D2H
| Tetrameric coiled-coil structure of liprin-alpha2_H2 | Descriptor: | GLYCEROL, Liprin-alpha-2 | Authors: | Liang, M, Wei, Z. | Deposit date: | 2020-09-16 | Release date: | 2021-04-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Oligomerized liprin-alpha promotes phase separation of ELKS for compartmentalization of presynaptic active zone proteins. Cell Rep, 34, 2021
|
|
7D2G
| Coiled-coil structure of liprin-alpha2_H2delC | Descriptor: | GLYCEROL, Liprin-alpha-2 | Authors: | Liang, M, Wei, Z. | Deposit date: | 2020-09-16 | Release date: | 2021-04-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Oligomerized liprin-alpha promotes phase separation of ELKS for compartmentalization of presynaptic active zone proteins. Cell Rep, 34, 2021
|
|
7DDX
| Crystal structure of KANK1 S1179F mutant in complex wtih eIF4A1 | Descriptor: | Eukaryotic initiation factor 4A-I, GLYCEROL, KN motif and ankyrin repeat domains 1, ... | Authors: | Pan, W, Xu, Y, Wei, Z. | Deposit date: | 2020-10-30 | Release date: | 2021-09-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Nephrotic-syndrome-associated mutation of KANK2 induces pathologic binding competition with physiological interactor KIF21A. J.Biol.Chem., 297, 2021
|
|
8IJ9
| Crystal structure of the ELKS1/Rab6B complex | Descriptor: | ELKS/Rab6-interacting/CAST family member 1, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Jin, G, Wei, Z. | Deposit date: | 2023-02-26 | Release date: | 2023-06-14 | Last modified: | 2023-06-28 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Structural basis of ELKS/Rab6B interaction and its role in vesicle capturing enhanced by liquid-liquid phase separation. J.Biol.Chem., 299, 2023
|
|
8IW5
| Crystal structure of liprin-beta H2H3 dimer | Descriptor: | CALCIUM ION, Liprin-beta-1 | Authors: | Zhang, J, Chen, S, Wei, Z. | Deposit date: | 2023-03-29 | Release date: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | KANK1 shapes focal adhesions by orchestrating protein binding, mechanical force sensing, and phase separation. Cell Rep, 42, 2023
|
|
8IVZ
| Crystal structure of talin R7 in complex with KANK1 KN motif | Descriptor: | KN motif and ankyrin repeat domains 1, Talin-1 | Authors: | Xu, Y, Li, K, Wei, Z, Cong, Y. | Deposit date: | 2023-03-29 | Release date: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | KANK1 shapes focal adhesions by orchestrating protein binding, mechanical force sensing, and phase separation. Cell Rep, 42, 2023
|
|
8IW0
| Crystal structure of the KANK1/liprin-beta1 complex | Descriptor: | Liprin-beta-1,KN motif and ankyrin repeat domain-containing protein 1 | Authors: | Zhang, J, Chen, S, Wei, Z, Yu, C. | Deposit date: | 2023-03-29 | Release date: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | KANK1 shapes focal adhesions by orchestrating protein binding, mechanical force sensing, and phase separation. Cell Rep, 42, 2023
|
|
7Y8W
| Crystal structure of DLC-1/SAO-1 complex | Descriptor: | Dynein light chain 1, cytoplasmic, GLYCEROL, ... | Authors: | Yan, H, Zhao, C, Wei, Z, Yu, C. | Deposit date: | 2022-06-24 | Release date: | 2023-07-26 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Interaction between DLC-1 and SAO-1 facilitates CED-4 translocation during apoptosis in the Caenorhabditis elegans germline. Cell Death Discov, 8, 2022
|
|
7YV9
| |
5Y7N
| Crystal structure of AKR1B10 in complex with NADP+ and Androst-4-ene-3-beta-6-alpha-diol | Descriptor: | (3S,6S,8S,9S,10R,13S,14R)-10,13-dimethyl-2,3,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,6-diol, Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Hong, Z, Liping, Z, Cuiyun, L, Wei, Z. | Deposit date: | 2017-08-17 | Release date: | 2018-08-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural determinants for the inhibition of AKR1B10 by steroids To Be Published
|
|
6F4V
| |
6F4U
| |