8A46
 
 | | Crystal structure of the human Kelch domain of Keap1 in complex with compound S217879 | | Descriptor: | 2-[(1S,2R,8S)-2,4,32-trimethyl-28,28-bis(oxidanylidene)-19,22,27-trioxa-28$l^{6}-thia-1,14,15,16-tetrazahexacyclo[21.5.3.1^{3,7}.1^{9,13}.0^{12,16}.0^{26,30}]tritriaconta-3(33),4,6,9(32),10,12,14,23,25,30-decaen-8-yl]ethanoic acid, Kelch-like ECH-associated protein 1 | | Authors: | Weber, C, Vuillard, L, Delerive, P, Miallau, L. | | Deposit date: | 2022-06-10 | | Release date: | 2022-07-13 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.323 Å) | | Cite: | Selective disruption of NRF2-KEAP1 interaction leads to NASH resolution and reduction of liver fibrosis in mice.
JHEP Rep, 5, 2023
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1A03
 | | THE THREE-DIMENSIONAL STRUCTURE OF CA2+-BOUND CALCYCLIN: IMPLICATIONS FOR CA2+-SIGNAL TRANSDUCTION BY S100 PROTEINS, NMR, 20 STRUCTURES | | Descriptor: | CALCYCLIN (RABBIT, CA2+) | | Authors: | Sastry, M, Ketchem, R.R, Crescenzi, O, Weber, C, Lubienski, M.J, Hidaka, H, Chazin, W.J. | | Deposit date: | 1997-12-08 | | Release date: | 1999-03-02 | | Last modified: | 2022-02-16 | | Method: | SOLUTION NMR | | Cite: | The three-dimensional structure of Ca(2+)-bound calcyclin: implications for Ca(2+)-signal transduction by S100 proteins.
Structure, 6, 1998
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8A66
 | | Crystal structure of MST2 in complex with XMU-MP-1 | | Descriptor: | 4-[(5,10-dimethyl-6-oxo-6,10-dihydro-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide, SODIUM ION, Serine/threonine-protein kinase 3 36kDa subunit | | Authors: | Nawrotek, A, Vuillard, L, Miallau, L, Weber, C. | | Deposit date: | 2022-06-16 | | Release date: | 2022-07-20 | | Last modified: | 2022-12-07 | | Method: | X-RAY DIFFRACTION (1.901 Å) | | Cite: | Crystal structure of the Kelch domain of human Keap1in complex with ligand S217879
To Be Published
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