7T2U
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8EUA
| Structure of SARS-CoV2 PLpro bound to a covalent inhibitor | Descriptor: | Papain-like protease nsp3, SULFATE ION, ZINC ION, ... | Authors: | Mathews, I.I, Pokhrel, S, Wakatsuki, S. | Deposit date: | 2022-10-18 | Release date: | 2023-04-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Potent and selective covalent inhibition of the papain-like protease from SARS-CoV-2. Nat Commun, 14, 2023
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6XZC
| CryoEM structure of the ring-shaped virulence factor EspB from Mycobacterium tuberculosis | Descriptor: | ESX-1 secretion-associated protein EspB | Authors: | Piton, J, Pojer, F, Wakatsuki, S, Gati, C, Cole, S.T. | Deposit date: | 2020-02-03 | Release date: | 2020-06-17 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | High resolution CryoEM structure of the ring-shaped virulence factor EspB fromMycobacterium tuberculosis. J Struct Biol X, 4, 2020
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4XKH
| CRYSTAL STRUCTURE OF THE AIRAPL TANDEM UIMS IN COMPLEX WITH A LYS48-LINKED TRI-UBIQUITIN | Descriptor: | AN1-type zinc finger protein 2B, Polyubiquitin-C | Authors: | Rahighi, S, Kawasaki, M, Stanhill, A, Wakatsuki, S. | Deposit date: | 2015-01-11 | Release date: | 2016-02-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Selective Binding of AIRAPL Tandem UIMs to Lys48-Linked Tri-Ubiquitin Chains. Structure, 24, 2016
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7SEI
| Glucose-6-phosphate 1-dehydrogenase (K403Q) | Descriptor: | Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Mathews, I.I, Garcia, A.A, Wakatsuki, S, Mochly-Rosen, D. | Deposit date: | 2021-09-30 | Release date: | 2022-08-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | Stabilization of glucose-6-phosphate dehydrogenase oligomers enhances catalytic activity and stability of clinical variants. J.Biol.Chem., 298, 2022
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7SEH
| Glucose-6-phosphate 1-dehydrogenase (K403QdLtL) | Descriptor: | Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Mathews, I.I, Garcia, A.A, Wakatsuki, S, Mochly-Rosen, D. | Deposit date: | 2021-09-30 | Release date: | 2022-08-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Stabilization of glucose-6-phosphate dehydrogenase oligomers enhances catalytic activity and stability of clinical variants. J.Biol.Chem., 298, 2022
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4WAA
| Crystal structure of Nix LIR-fused human LC3B_2-119 | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B | Authors: | Suzuki, H, Ravichandran, A.C, Dobson, R.C.J, Novak, I, Wakatsuki, S. | Deposit date: | 2014-08-29 | Release date: | 2015-09-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Phosphorylation of the mitochondrial autophagy receptor Nix enhances its interaction with LC3 proteins. Sci Rep, 7, 2017
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6P5T
| Surface-layer (S-layer) RsaA protein from Caulobacter crescentus bound to strontium and iodide | Descriptor: | IODIDE ION, S-layer protein, STRONTIUM ION | Authors: | Chan, A.C, Herrmann, J, Smit, J, Wakatsuki, S, Murphy, M.E. | Deposit date: | 2019-05-30 | Release date: | 2020-01-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A bacterial surface layer protein exploits multistep crystallization for rapid self-assembly. Proc.Natl.Acad.Sci.USA, 117, 2020
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1A2X
| COMPLEX OF TROPONIN C WITH A 47 RESIDUE (1-47) FRAGMENT OF TROPONIN I | Descriptor: | CALCIUM ION, TROPONIN C, TROPONIN I | Authors: | Vassylyev, D.G, Takeda, S, Wakatsuki, S, Maeda, K, Maeda, Y. | Deposit date: | 1998-01-13 | Release date: | 1998-07-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of troponin C in complex with troponin I fragment at 2.3-A resolution. Proc.Natl.Acad.Sci.USA, 95, 1998
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6E07
| Crystal structure of Canton G6PD in complex with structural NADP | Descriptor: | GLYCEROL, Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Rahighi, S, Mochly-Rosen, D, Wakatsuki, S. | Deposit date: | 2018-07-06 | Release date: | 2018-07-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Correcting glucose-6-phosphate dehydrogenase deficiency with a small-molecule activator. Nat Commun, 9, 2018
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6E08
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3H3Q
| Crystal structure of the CERT START domain in complex with HPA-13 | Descriptor: | Goodpasture antigen binding protein, N-[(1R,3R)-3-hydroxy-1-(hydroxymethyl)-3-phenylpropyl]tridecanamide | Authors: | Kudo, N, Wakatsuki, S, Kato, R. | Deposit date: | 2009-04-17 | Release date: | 2010-03-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of the CERT START domain with inhibitors provide insights into the mechanism of ceramide transfer. J.Mol.Biol., 396, 2010
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3H3R
| Crystal structure of the CERT START domain in complex with HPA-14 | Descriptor: | Goodpasture antigen binding protein, N-[(1R,3R)-3-hydroxy-1-(hydroxymethyl)-3-phenylpropyl]tetradecanamide | Authors: | Kudo, N, Wakatsuki, S, Kato, R. | Deposit date: | 2009-04-17 | Release date: | 2010-03-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structures of the CERT START domain with inhibitors provide insights into the mechanism of ceramide transfer. J.Mol.Biol., 396, 2010
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1EBE
| Laue diffraction study on the structure of cytochrome c peroxidase compound I | Descriptor: | CYTOCHROME C PEROXIDASE, OXYGEN ATOM, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Fulop, V, Phizackerley, R.P, Soltis, S.M, Clifton, I.J, Wakatsuki, S, Erman, J.E, Hajdu, J, Edwards, S.L. | Deposit date: | 2001-07-25 | Release date: | 2001-07-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Laue Diffraction Study on the Structure of Cytochrome C Peroxidase Compound I Structure, 2, 1994
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4Z4K
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4Z4M
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7T2V
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7T2T
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4FW9
| Crystal structure of the Lon-like protease MtaLonC | Descriptor: | PHOSPHATE ION, TTC1975 peptidase | Authors: | Chang, C.I, Ihara, K, Kuo, C.I, Huang, K.F, Wakatsuki, S. | Deposit date: | 2012-06-30 | Release date: | 2013-06-26 | Last modified: | 2013-09-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of an ATP-independent Lon-like protease and its complexes with covalent inhibitors Acta Crystallogr.,Sect.D, 69, 2013
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1F2D
| 1-AMINOCYCLOPROPANE-1-CARBOXYLATE DEAMINASE | Descriptor: | 1-AMINOCYCLOPROPANE-1-CARBOXYLATE DEAMINASE, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION | Authors: | Yao, M, Ose, T, Sugimoto, H, Horiuchi, A, Nakagawa, A, Yokoi, D, Murakami, T, Honma, M, Wakatsuki, S, Tanaka, I. | Deposit date: | 2000-05-24 | Release date: | 2000-12-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of 1-aminocyclopropane-1-carboxylate deaminase from Hansenula saturnus. J.Biol.Chem., 275, 2000
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4NC5
| Human sialidase 2 in complex with 2,3-difluorosialic acid (covalent intermediate) | Descriptor: | 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, PHOSPHATE ION, Sialidase-2 | Authors: | Buchini, S, Gallat, F.-X, Greig, I.R, Kim, J.-H, Wakatsuki, S, Chavas, L.M.G, Withers, S.G. | Deposit date: | 2013-10-24 | Release date: | 2013-11-06 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.513 Å) | Cite: | Tuning mechanism-based inactivators of neuraminidases: mechanistic and structural insights. Angew.Chem.Int.Ed.Engl., 53, 2014
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4NCS
| Human sialidase 2 in complex with 2,3-difluorosialic acid (covalent intermediate) | Descriptor: | (2S,3S,4R,5R,6R)-5-acetamido-2,3-bis(fluoranyl)-4-oxidanyl-6-[(1S,2S)-1,2,3-tris(oxidanyl)propyl]oxane-2-carboxylic acid, PHOSPHATE ION, Sialidase-2 | Authors: | Buchini, S, Gallat, F.-X, Greig, I.R, Kim, J.-H, Wakatsuki, S, Chavas, L.M.G, Withers, S.G. | Deposit date: | 2013-10-25 | Release date: | 2013-12-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.201 Å) | Cite: | Tuning mechanism-based inactivators of neuraminidases: mechanistic and structural insights. Angew.Chem.Int.Ed.Engl., 53, 2014
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3F89
| NEMO CoZi domain | Descriptor: | NF-kappa-B essential modulator | Authors: | Rahighi, S, Ikeda, F, Kawasaki, M, Akutsu, M, Suzuki, N, Kato, R, Kensche, T, Uejima, T, Bloor, S, Komander, D, Randow, F, Wakatsuki, S, Dikic, I. | Deposit date: | 2008-11-11 | Release date: | 2009-03-24 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation Cell(Cambridge,Mass.), 136, 2009
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6VA7
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6VA8
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