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PDB: 8 results
8SH1
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BU of 8sh1 by Molmil
Structure of human POT1 DNA binding domain bound to a 5'-phosphorylated junction of a telomeric double-stranded DNA duplex with a 3'-overhang
Descriptor: DNA (5'-D(*CP*GP*CP*GP*CP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3'), DNA (5'-D(P*CP*TP*AP*AP*CP*GP*CP*GP*CP*G)-3'), Protection of telomeres protein 1
Authors:Nandakumar, J, Tesmer, V.M.
Deposit date:2023-04-13
Release date:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Human POT1 protects the telomeric ds-ss DNA junction by capping the 5' end of the chromosome.
Science, 381, 2023
8SH0
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BU of 8sh0 by Molmil
Structure of human POT1 DNA binding domain bound to a 5'-phosphorylated junction of a telomeric DNA hairpin with a 3'-overhang
Descriptor: ACETATE ION, DNA (5'-D(P*CP*CP*AP*GP*CP*AP*GP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3'), Protection of telomeres protein 1
Authors:Nandakumar, J, Tesmer, V.M.
Deposit date:2023-04-13
Release date:2023-08-30
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Human POT1 protects the telomeric ds-ss DNA junction by capping the 5' end of the chromosome.
Science, 381, 2023
2ACX
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BU of 2acx by Molmil
Crystal Structure of G protein coupled receptor kinase 6 bound to AMPPNP
Descriptor: G protein-coupled receptor kinase 6, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Lodowski, D.T, Tesmer, V.M, Benovic, J.L, Tesmer, J.J.
Deposit date:2005-07-19
Release date:2006-04-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Structure of G Protein-coupled Receptor Kinase (GRK)-6 Defines a Second Lineage of GRKs.
J.Biol.Chem., 281, 2006
3UZT
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BU of 3uzt by Molmil
Structure of the C13.18 RNA Aptamer in Complex with G Protein-Coupled Receptor Kinase 2
Descriptor: Beta-adrenergic receptor kinase 1, C13.18 RNA Aptamer, MAGNESIUM ION
Authors:Tesmer, J.J.G, Tesmer, V.M.
Deposit date:2011-12-07
Release date:2012-07-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.51 Å)
Cite:Molecular mechanism for inhibition of g protein-coupled receptor kinase 2 by a selective RNA aptamer.
Structure, 20, 2012
3UZS
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BU of 3uzs by Molmil
Structure of the C13.28 RNA Aptamer Bound to the G Protein-Coupled Receptor Kinase 2-Heterotrimeric G Protein Beta 1 and Gamma 2 Subunit Complex
Descriptor: Beta-adrenergic receptor kinase 1, C13.28 RNA Aptamer, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Tesmer, J.J.G, Tesmer, V.M.
Deposit date:2011-12-07
Release date:2012-07-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (4.52 Å)
Cite:Molecular mechanism for inhibition of g protein-coupled receptor kinase 2 by a selective RNA aptamer.
Structure, 20, 2012
3KRW
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BU of 3krw by Molmil
Human GRK2 in complex with Gbetgamma subunits and balanol (soak)
Descriptor: BALANOL, Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Tesmer, J.J.G, Tesmer, V.M.
Deposit date:2009-11-19
Release date:2010-02-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of human g protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol.
J.Med.Chem., 53, 2010
3KRX
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BU of 3krx by Molmil
Human GRK2 in complex with Gbetgamma subunits and balanol (co-crystal)
Descriptor: BALANOL, Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Tesmer, J.J.G, Tesmer, V.M.
Deposit date:2009-11-19
Release date:2010-02-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of human g protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol.
J.Med.Chem., 53, 2010
5WIR
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BU of 5wir by Molmil
Structure of the TRF1-TERB1 interface
Descriptor: TERB1-TBM, Telomeric repeat-binding factor 1
Authors:Nandakumar, J, Pendlebury, D.F, Smith, E.M, Tesmer, V.M.
Deposit date:2017-07-20
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Dissecting the telomere-inner nuclear membrane interface formed in meiosis.
Nat. Struct. Mol. Biol., 24, 2017

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