2ACX

Crystal Structure of G protein coupled receptor kinase 6 bound to AMPPNP

Summary for 2ACX

• Entry DOI: 10.2210/pdb2acx/pdb
• Descriptor: G protein-coupled receptor kinase 6, MAGNESIUM ION, PHOSPHATE ION, ... (5 entities in total)
• Functional Keywords: kinase, g protein, grk, g protein coupled receptor kinase, grk6, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Membrane; Lipid-anchor: P43250
• Total number of polymer chains: 2
• Total formula weight: 133272.35

Authors

Lodowski, D.T.,Tesmer, V.M.,Benovic, J.L.,Tesmer, J.J. (deposition date: 2005-07-19, release date: 2006-04-25, Last modification date: 2023-08-23)

• Primary citation: Lodowski, D.T.,Tesmer, V.M.,Benovic, J.L.,Tesmer, J.J.; The Structure of G Protein-coupled Receptor Kinase (GRK)-6 Defines a Second Lineage of GRKs.; J.Biol.Chem., 281:16785-16793, 2006; PubMed: 16613860; DOI: 10.1074/jbc.M601327200

Experimental method

X-RAY DIFFRACTION (2.6 Å)