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PDB: 10 results

8SPM
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BU of 8spm by Molmil
Crystal structure of NikA in complex Ni-AMA
Descriptor: Aspergillomarasmine A, NICKEL (II) ION, Nickel ABC transporter, ...
Authors:Sychantha, D, Prehna, G, Wright, G.D.
Deposit date:2023-05-03
Release date:2024-04-10
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Targeting bacterial nickel transport inhibits virulence-associated Ni-dependent enzymes
To Be Published
8UK6
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BU of 8uk6 by Molmil
Candida albicans glutaminyl tRNA synthetase (GLN4) in complex with N-pyrimidinyl-beta-thiophenylacrylamide
Descriptor: (2E)-N-(pyrimidin-2-yl)-3-(thiophen-2-yl)prop-2-enamide, ZINC ION, glutamine--tRNA ligase
Authors:Sychantha, D, Wright, G.D.
Deposit date:2023-10-12
Release date:2024-03-06
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-beta-thiophenylacrylamides exerts highly selective antifungal activity.
Cell Chem Biol, 2024
6BT4
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Crystal structure of the SLH domain of Sap from Bacillus anthracis in complex with a pyruvylated SCWP unit
Descriptor: 2-(acetylamino)-4-O-{2-(acetylamino)-4,6-O-[(1S)-1-carboxyethylidene]-2-deoxy-beta-D-mannopyranosyl}-2-deoxy-beta-D-glucopyranose, S-layer protein sap, SULFATE ION
Authors:Sychantha, D, Chapman, R.N, Bamford, N.C, Boons, G.J, Howell, P.L, Clarke, A.J.
Deposit date:2017-12-05
Release date:2018-03-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.306 Å)
Cite:Molecular Basis for the Attachment of S-Layer Proteins to the Cell Wall of Bacillus anthracis.
Biochemistry, 57, 2018
5UG1
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BU of 5ug1 by Molmil
Structure of Streptococcus pneumoniae peptidoglycan O-acetyltransferase A (OatA) C-terminal catalytic domain with methylsulfonyl adduct
Descriptor: Acyltransferase, SODIUM ION, methanesulfonic acid
Authors:Sychantha, D, Jones, C, Little, D.J, Moynihan, P.J, Robinson, H, Galley, N.F, Roper, D.I, Dowson, C.G, Howell, P.L, Clarke, A.J.
Deposit date:2017-01-06
Release date:2017-10-25
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:In vitro characterization of the antivirulence target of Gram-positive pathogens, peptidoglycan O-acetyltransferase A (OatA).
PLoS Pathog., 13, 2017
5V8D
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BU of 5v8d by Molmil
Structure of Bacillus cereus PatB1 with sulfonyl adduct
Descriptor: Bacillus cereus PatB1, SULFATE ION
Authors:Sychantha, D, Little, D.J, Chapman, R.N, Boons, G.J, Robinson, H, Howell, P.L, Clarke, A.J.
Deposit date:2017-03-21
Release date:2017-10-18
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:PatB1 is an O-acetyltransferase that decorates secondary cell wall polysaccharides.
Nat. Chem. Biol., 14, 2018
5UFY
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BU of 5ufy by Molmil
Structure of Streptococcus pneumoniae peptidoglycan O-acetyltransferase A (OatA) C-terminal catalytic domain
Descriptor: Acyltransferase, SODIUM ION
Authors:Sychantha, D, Jones, C, Little, D.J, Moynihan, P.J, Robinson, H, Galley, N.F, Roper, D.I, Dowson, C.G, Howell, P.L, Clarke, A.J.
Deposit date:2017-01-06
Release date:2017-10-25
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:In vitro characterization of the antivirulence target of Gram-positive pathogens, peptidoglycan O-acetyltransferase A (OatA).
PLoS Pathog., 13, 2017
5V8E
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BU of 5v8e by Molmil
Structure of Bacillus cereus PatB1
Descriptor: Bacillus cereus PatB1, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Sychantha, D, Little, D.J, Chapman, R.N, Boons, G.J, Robinson, H, Howell, P.L, Clarke, A.J.
Deposit date:2017-03-21
Release date:2017-10-18
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:PatB1 is an O-acetyltransferase that decorates secondary cell wall polysaccharides.
Nat. Chem. Biol., 14, 2018
7MK5
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BU of 7mk5 by Molmil
Crystal structure of Escherichia coli ClpP covalently inhibited by clipibicyclene
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-[(1E)-3-{[(2E,4E,6E,8S)-8-hydroxy-4-methyldeca-2,4,6-trienoyl]amino}-3-oxoprop-1-en-1-yl]azete-1(2H)-carboxylic acid, ACETATE ION, ...
Authors:Culp, E.J, Sychantha, D, Hobson, C, Pawlowski, A.J, Prehna, G, Wright, G.D.
Deposit date:2021-04-21
Release date:2022-02-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:ClpP inhibitors are produced by a widespread family of bacterial gene clusters.
Nat Microbiol, 7, 2022
6VJP
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BU of 6vjp by Molmil
Structure of Staphylococcus aureus peptidoglycan O-acetyltransferase A (OatA) C-terminal catalytic domain
Descriptor: Acetyltransferase, SODIUM ION
Authors:Jones, C.J, Sychantha, D, Howell, P.L, Clarke, A.J.
Deposit date:2020-01-16
Release date:2020-05-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.711 Å)
Cite:Structural basis for theO-acetyltransferase function of the extracytoplasmic domain of OatA fromStaphylococcus aureus.
J.Biol.Chem., 295, 2020
6WN9
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BU of 6wn9 by Molmil
Structure of Staphylococcus aureus peptidoglycan O-acetyltransferase A (OatA) C-terminal catalytic domain, Zn-bound
Descriptor: Acetyltransferase, ZINC ION
Authors:Jones, C.J, Sychantha, D, Howell, P.L, Clarke, A.J.
Deposit date:2020-04-22
Release date:2020-05-06
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis for theO-acetyltransferase function of the extracytoplasmic domain of OatA fromStaphylococcus aureus.
J.Biol.Chem., 295, 2020

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