5H1C
 
 | | Human RAD51 post-synaptic complexes | | Descriptor: | DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA repair protein RAD51 homolog 1, ... | | Authors: | Xu, J, Zhao, L, Xu, Y, Zhao, W, Sung, P, Wang, H.W. | | Deposit date: | 2016-10-08 | | Release date: | 2016-12-21 | | Last modified: | 2022-03-23 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Cryo-EM structures of human RAD51 recombinase filaments during catalysis of DNA-strand exchange
Nat. Struct. Mol. Biol., 24, 2017
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8W1O
 | | Cryo-EM structure of BTV virion | | Descriptor: | Core protein VP3, Outer capsid protein VP2, RNA-1, ... | | Authors: | Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H. | | Deposit date: | 2024-02-16 | | Release date: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells.
Cell, 2024
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5H1B
 | | Human RAD51 presynaptic complex | | Descriptor: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA repair protein RAD51 homolog 1, MAGNESIUM ION, ... | | Authors: | Xu, J, Zhao, L, Xu, Y, Zhao, W, Sung, P, Wang, H.W. | | Deposit date: | 2016-10-08 | | Release date: | 2016-12-21 | | Last modified: | 2022-03-23 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Cryo-EM structures of human RAD51 recombinase filaments during catalysis of DNA-strand exchange
Nat. Struct. Mol. Biol., 24, 2017
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8W12
 | | Cryo-EM structure of VP3-VP6 heterohexamer | | Descriptor: | Core protein VP3, VP6 | | Authors: | Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H. | | Deposit date: | 2024-02-14 | | Release date: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells.
Cell, 2024
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8W19
 | | Cryo-EM structure of BTV star-subcore | | Descriptor: | Core protein VP3, VP6 | | Authors: | Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H. | | Deposit date: | 2024-02-15 | | Release date: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells.
Cell, 2024
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8W1C
 | | Cryo-EM structure of BTV pre-subcore | | Descriptor: | Core protein VP3, VP6 | | Authors: | Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H. | | Deposit date: | 2024-02-15 | | Release date: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells.
Cell, 2024
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8W1I
 | | Cryo-EM structure of BTV subcore | | Descriptor: | Core protein VP3 | | Authors: | Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H. | | Deposit date: | 2024-02-16 | | Release date: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (6.5 Å) | | Cite: | RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells.
Cell, 2024
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8W1R
 | | Cryo-EM structure of BTV core | | Descriptor: | Core protein VP3, RNA-directed RNA polymerase | | Authors: | Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H. | | Deposit date: | 2024-02-17 | | Release date: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells.
Cell, 2024
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8W1S
 | | Cryo-EM structure of BTV pre-core | | Descriptor: | Core protein VP3, RNA-directed RNA polymerase | | Authors: | Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H. | | Deposit date: | 2024-02-17 | | Release date: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells.
Cell, 2024
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4REB
 | | Structural Insights into 5' Flap DNA Unwinding and Incision by the Human FAN1 Dimer | | Descriptor: | DNA (5'-D(P*CP*GP*TP*GP*GP*CP*GP*AP*GP*CP*GP*CP*TP*CP*GP*CP*CP*AP*CP*G)-3'), DNA (5'-D(P*GP*CP*TP*CP*GP*CP*CP*AP*CP*G)-3'), DNA (5'-D(P*GP*TP*GP*GP*CP*GP*AP*GP*C)-3'), ... | | Authors: | Zhao, Q, Xue, X, Longerich, S, Sung, P, Xiong, Y. | | Deposit date: | 2014-09-22 | | Release date: | 2014-12-24 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (4.2 Å) | | Cite: | Structural insights into 5' flap DNA unwinding and incision by the human FAN1 dimer.
Nat Commun, 5, 2014
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4REA
 | | A Nuclease DNA complex | | Descriptor: | DNA (5'-D(*TP*GP*CP*TP*CP*GP*CP*CP*AP*C)-3'), DNA (5'-D(P*CP*GP*TP*GP*GP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*GP*GP*CP*GP*AP*GP*CP*GP*CP*TP*CP*GP*CP*CP*AP*CP*G)-3'), ... | | Authors: | Zhao, Q, Xue, X, Longerich, S, Sung, P, Xiong, Y. | | Deposit date: | 2014-09-22 | | Release date: | 2014-12-24 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.81 Å) | | Cite: | Structural insights into 5' flap DNA unwinding and incision by the human FAN1 dimer.
Nat Commun, 5, 2014
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4REC
 | | A nuclease-DNA complex form 3 | | Descriptor: | DNA (40-MER), Fanconi-associated nuclease 1, IODIDE ION | | Authors: | Zhao, Q, Xue, X, Longerich, S, Sung, P, Xiong, Y. | | Deposit date: | 2014-09-22 | | Release date: | 2014-12-24 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural insights into 5' flap DNA unwinding and incision by the human FAN1 dimer.
Nat Commun, 5, 2014
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4NE1
 | | Human MHF1 MHF2 DNA complexes | | Descriptor: | Centromere protein S, Centromere protein X, DNA (26-MER) | | Authors: | Zhao, Q, Saro, D, Sachpatzidis, A, Sung, P, Xiong, Y. | | Deposit date: | 2013-10-28 | | Release date: | 2014-01-22 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (6.499 Å) | | Cite: | The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
Nat Commun, 5, 2014
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2MH2
 | | Structural insights into the DNA recognition and protein interaction domains reveal fundamental homologous DNA pairing properties of HOP2 | | Descriptor: | Homologous-pairing protein 2 homolog | | Authors: | Moktan, H, Guiraldelli, M.F, Eyter, C.A, Zhao, W, Camerini-Otero, R.D, Sung, P, Zhou, D.H, Pezza, R.J. | | Deposit date: | 2013-11-13 | | Release date: | 2014-04-16 | | Last modified: | 2014-08-06 | | Method: | SOLUTION NMR | | Cite: | Solution Structure and DNA-binding Properties of the Winged Helix Domain of the Meiotic Recombination HOP2 Protein.
J.Biol.Chem., 289, 2014
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4NDY
 | | Human MHF1-MHF2 DNA complex | | Descriptor: | Centromere protein S, Centromere protein X, DNA (26-MER) | | Authors: | Zhao, Q, Saro, D, Sachpatzidis, A, Sung, P, Xiong, Y. | | Deposit date: | 2013-10-28 | | Release date: | 2014-01-22 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (6.999 Å) | | Cite: | The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
Nat Commun, 5, 2014
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8FY0
 | | E3:PROTAC:target ternary complex structure (VCB/753b/BCL-xL) | | Descriptor: | Bcl-2-like protein 1, CACODYLIC ACID, Elongin-B, ... | | Authors: | Olsen, S.K, Nayak, D, Lv, D, Yuan, Y, Zhang, P, Hu, W, Lv, Z, Sung, P, Hromas, R, Zheng, G, Zhou, D. | | Deposit date: | 2023-01-25 | | Release date: | 2024-04-10 | | Method: | X-RAY DIFFRACTION (2.94 Å) | | Cite: | Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL.
Nat Commun, 15, 2024
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8FY2
 | | E3:PROTAC:target ternary complex structure (VCB/WH244/BCL-2) | | Descriptor: | Apoptosis regulator Bcl-2, Elongin-B, Elongin-C, ... | | Authors: | Nayak, D, Lv, D, Yuan, Y, Zhang, P, Hu, W, Ruben, E, Lv, Z, Sung, P, Hromas, R, Zheng, G, Zhou, D, Olsen, S.K. | | Deposit date: | 2023-01-25 | | Release date: | 2024-04-10 | | Method: | X-RAY DIFFRACTION (2.98 Å) | | Cite: | Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL.
Nat Commun, 15, 2024
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8FY1
 | | E3:PROTAC:target ternary complex structure (VCB/753b/BCL-2) | | Descriptor: | Apoptosis regulator Bcl-2, Elongin-B, Elongin-C, ... | | Authors: | Nayak, D, Lv, D, Yuan, Y, Zhang, P, Hu, W, Lv, Z, Sung, P, Hromas, R, Zheng, G, Zhou, D, Olsen, S.K. | | Deposit date: | 2023-01-25 | | Release date: | 2024-04-10 | | Method: | X-RAY DIFFRACTION (2.56 Å) | | Cite: | Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL.
Nat Commun, 15, 2024
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8GBJ
 | | Cryo-EM structure of a human BCDX2/ssDNA complex | | Descriptor: | DNA (5'-D(P*CP*CP*CP*CP*CP*C)-3'), DNA repair protein RAD51 homolog 2, DNA repair protein RAD51 homolog 3, ... | | Authors: | Jia, L, Wasmuth, E.V, Ruben, E.A, Sung, P, Rawal, Y, Greene, E.C, Meir, A, Olsen, S.K. | | Deposit date: | 2023-02-26 | | Release date: | 2023-06-21 | | Last modified: | 2023-08-02 | | Method: | ELECTRON MICROSCOPY (3.11 Å) | | Cite: | Structural insights into BCDX2 complex function in homologous recombination.
Nature, 619, 2023
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6E49
 | | Pif1 peptide bound to PCNA trimer | | Descriptor: | ATP-dependent DNA helicase PIF1, Proliferating cell nuclear antigen | | Authors: | Buzovetsky, O, Kwon, Y, Pham, N.T, Kim, C, Ira, G, Sung, P, Xiong, Y. | | Deposit date: | 2018-07-17 | | Release date: | 2018-08-22 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Role of the Pif1-PCNA Complex in Pol delta-Dependent Strand Displacement DNA Synthesis and Break-Induced Replication.
Cell Rep, 21, 2017
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4NE5
 | | Human MHF1-MHF2 complex | | Descriptor: | Centromere protein S, Centromere protein X | | Authors: | Zhao, Q, Saro, D, Sachpatzidis, A, Sung, P, Xiong, Y. | | Deposit date: | 2013-10-28 | | Release date: | 2013-12-25 | | Last modified: | 2014-02-12 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
Nat Commun, 5, 2014
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3NBI
 | | Crystal structure of human RMI1 N-terminus | | Descriptor: | RecQ-mediated genome instability protein 1 | | Authors: | Wang, F, Yang, Y, Singh, T.R, Busygina, V, Guo, R, Wan, K, Wang, W, Sung, P, Meetei, A.R, Lei, M. | | Deposit date: | 2010-06-03 | | Release date: | 2010-09-22 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structures of RMI1 and RMI2, Two OB-Fold Regulatory Subunits of the BLM Complex.
Structure, 18, 2010
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3NBH
 | | Crystal structure of human RMI1C-RMI2 complex | | Descriptor: | RecQ-mediated genome instability protein 1, RecQ-mediated genome instability protein 2 | | Authors: | Wang, F, Yang, Y, Singh, T.R, Busygina, V, Guo, R, Wan, K, Wang, W, Sung, P, Meetei, A.R, Lei, M. | | Deposit date: | 2010-06-03 | | Release date: | 2010-09-22 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structures of RMI1 and RMI2, Two OB-Fold Regulatory Subunits of the BLM Complex.
Structure, 18, 2010
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4NE6
 | | Human MHF1-MHF2 complex | | Descriptor: | Centromere protein S, Centromere protein X | | Authors: | Zhao, Q, Saro, D, Sachpatzidis, A, Sung, P, Xiong, Y. | | Deposit date: | 2013-10-28 | | Release date: | 2013-12-25 | | Last modified: | 2014-02-12 | | Method: | X-RAY DIFFRACTION (2.1001 Å) | | Cite: | The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
Nat Commun, 5, 2014
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8FAZ
 | | Cryo-EM structure of the human BCDX2 complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA repair protein RAD51 homolog 2, DNA repair protein RAD51 homolog 3, ... | | Authors: | Jia, L, Wasmuth, E.V, Ruben, E.A, Sung, P, Rawal, Y, Greene, E.C, Meir, A, Olsen, S.K. | | Deposit date: | 2022-11-29 | | Release date: | 2023-06-21 | | Last modified: | 2023-08-02 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | Structural insights into BCDX2 complex function in homologous recombination.
Nature, 619, 2023
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