3D6V
 
 | | Crystal structure of 4-(trifluoromethyldiazirinyl)phenylalanyl-tRNA synthetase | | Descriptor: | 4-(2,2,2-TRIFLUOROETHYL)-L-PHENYLALANINE, BETA-MERCAPTOETHANOL, Tyrosyl-tRNA synthetase | | Authors: | Liu, W, Tippmann, E, Mack, A.V, Schultz, P.G. | | Deposit date: | 2008-05-20 | | Release date: | 2008-05-27 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | A genetically encoded diazirine photocrosslinker in Escherichia coli
ChemBioChem, 8, 2007
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3D6U
 | | Crystal structure of 4-(trifluoromethyldiazirinyl)phenylalanyl-tRNA synthetase | | Descriptor: | 4-[3-(TRIFLUOROMETHYL)DIAZIRIDIN-3-YL]-L-PHENYLALANINE, BETA-MERCAPTOETHANOL, Tyrosyl-tRNA synthetase | | Authors: | Liu, W, Tippmann, E, Mack, A.V, Schultz, P.G. | | Deposit date: | 2008-05-20 | | Release date: | 2008-05-27 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | A genetically encoded diazirine photocrosslinker in Escherichia coli
ChemBioChem, 8, 2007
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4ZJ3
 | | Crystal structure of cephalexin bound acyl-enzyme intermediate of Val216AcrF mutant TEM1 beta-lactamase from Escherichia coli: E166N and V216AcrF mutant. | | Descriptor: | Beta-lactamase TEM | | Authors: | Xiao, H, Nasertorabi, F, Choi, S, Han, G.W, Reed, S.A, Stevens, R.C, Schultz, P.G. | | Deposit date: | 2015-04-29 | | Release date: | 2015-05-20 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Exploring the potential impact of an expanded genetic code on protein function.
Proc.Natl.Acad.Sci.USA, 112, 2015
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3FCA
 | | Genetic Incorporation of a Metal-ion Chelating Amino Acid into proteins as biophysical probe | | Descriptor: | Cysteine synthase, ZINC ION | | Authors: | Wang, F, Lee, H, Spraggon, G, Schultz, P.G. | | Deposit date: | 2008-11-21 | | Release date: | 2009-02-17 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.149 Å) | | Cite: | Genetic incorporation of a metal-ion chelating amino acid into proteins as a biophysical probe.
J.Am.Chem.Soc., 131, 2009
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2PW8
 | | Crystal structure of sulfo-hirudin complexed to thrombin | | Descriptor: | Hirudin variant-1, NICKEL (II) ION, SODIUM ION, ... | | Authors: | Liu, C.C, Brustad, E, Liu, W, Schultz, P.G. | | Deposit date: | 2007-05-10 | | Release date: | 2007-08-21 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Crystal structure of a biosynthetic sulfo-hirudin complexed to thrombin.
J.Am.Chem.Soc., 129, 2007
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1A4K
 | | DIELS ALDER CATALYTIC ANTIBODY WITH TRANSITION STATE ANALOGUE | | Descriptor: | ANTIBODY FAB, CADMIUM ION, [4-(4-ACETYLAMINO-PHENYL)-3,5-DIOXO-4-AZA-TRICYCLO[5.2.2.0 2,6]UNDEC-1-YLCARBAMOYLOXY]-ACETIC ACID | | Authors: | Spiller, B.W, Romesburg, F.E, Schultz, P.G, Stevens, R.C. | | Deposit date: | 1998-01-30 | | Release date: | 1998-05-13 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Immunological origins of binding and catalysis in a Diels-Alderase antibody.
Science, 279, 1998
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1D6V
 | | CONFORMATION EFFECTS IN BIOLOGICAL CATALYSIS INTRODUCED BY OXY-COPE ANTIBODY MATURATION | | Descriptor: | (1S,2S,5S)2-(4-GLUTARIDYLBENZYL)-5-PHENYL-1-CYCLOHEXANOL, CADMIUM ION, CHIMERIC GERMLINE PRECURSOR OF OXY-COPE CATALYTIC ANTIBODY AZ-28 (HEAVY CHAIN), ... | | Authors: | Mundorff, E.C, Hanson, M.A, Schultz, P.G, Stevens, R.C. | | Deposit date: | 1999-10-15 | | Release date: | 2000-02-09 | | Last modified: | 2017-06-21 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Conformational effects in biological catalysis: an antibody-catalyzed oxy-cope rearrangement.
Biochemistry, 39, 2000
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1CG7
 | | HMG PROTEIN NHP6A FROM SACCHAROMYCES CEREVISIAE | | Descriptor: | PROTEIN (NON HISTONE PROTEIN 6 A) | | Authors: | Allain, F.H.T, Yen, Y.M, Masse, J.E, Schultze, P, Dieckmann, T, Johnson, R.C, Feigon, J. | | Deposit date: | 1999-03-27 | | Release date: | 1999-10-14 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the HMG protein NHP6A and its interaction with DNA reveals the structural determinants for non-sequence-specific binding.
EMBO J., 18, 1999
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1D5B
 | | UNLIGANDED MATURE OXY-COPE CATALYTIC ANTIBODY | | Descriptor: | CADMIUM ION, chimeric OXY-COPE catalytic ANTIBODY AZ-28 (HEAVY chain), chimeric OXY-COPE catalytic ANTIBODY AZ-28 (light chain) | | Authors: | Mundorff, E.C, Hanson, M.A, Schultz, P.G, Stevens, R.C. | | Deposit date: | 1999-10-06 | | Release date: | 2000-02-09 | | Last modified: | 2017-06-21 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Conformational effects in biological catalysis: an antibody-catalyzed oxy-cope rearrangement.
Biochemistry, 39, 2000
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1D5I
 | | UNLIGANDED GERMLINE PRECURSOR OF AN OXY-COPE CATALYTIC ANTIBODY | | Descriptor: | CADMIUM ION, CHIMERIC GERMLINE PRECURSOR OF OXY-COPE CATALYTIC ANTIBODY AZ-28 (HEAVY CHAIN), CHIMERIC GERMLINE PRECURSOR OF OXY-COPE CATALYTIC ANTIBODY AZ-28 (LIGHT CHAIN) | | Authors: | Mundorff, E.C, Hanson, M.A, Schultz, P.G, Stevens, R.C. | | Deposit date: | 1999-10-07 | | Release date: | 2000-02-09 | | Last modified: | 2017-06-21 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Conformational effects in biological catalysis: an antibody-catalyzed oxy-cope rearrangement.
Biochemistry, 39, 2000
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1R3X
 | | INTRAMOLECULAR DNA TRIPLEX WITH RNA THIRD STRAND, NMR, 10 STRUCTURES | | Descriptor: | DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*TP*CP*TP*CP*TP*CP*T)-3'), RNA (5'-R(*UP*CP*UP*CP*UP*CP*UP*U)-3') | | Authors: | Gotfredsen, C.H, Schultze, P, Feigon, J. | | Deposit date: | 1998-02-06 | | Release date: | 1998-05-20 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of an Intramolecular Pyrimidine-Purine-Pyrimidine Triplex Containing an RNA Third Strand
J.Am.Chem.Soc., 120, 1998
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1T6H
 | | Crystal Structure T4 Lysozyme incorporating an unnatural amino acid p-iodo-L-phenylalanine at position 153 | | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme | | Authors: | Spraggon, G, Xie, J, Wang, L, Wu, N, Brock, A, Schultz, P.G. | | Deposit date: | 2004-05-06 | | Release date: | 2004-10-26 | | Last modified: | 2018-02-14 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | The site-specific incorporation of p-iodo-L-phenylalanine into proteins for structure determination.
Nat.Biotechnol., 22, 2004
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1UM4
 | | Catalytic Antibody 21H3 with hapten | | Descriptor: | (1R)-1-PHENYLETHYL 4-(ACETYLAMINO)BENZYLPHOSPHONATE, Antibody 21H3 H chain, Antibody 21H3 L chain | | Authors: | Beuscher IV, A.E, Reuter, J, Olson, A.J, Romesberg, F.E, Schultz, P.G, Wirsching, P, Janda, K.D, Lerner, R.A, Stevens, R.C. | | Deposit date: | 2003-09-23 | | Release date: | 2004-10-05 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural Studies of an Efficient Catalytic Antibody Operating by Ping-Pong and Induced Fit Mechanisms
To be Published
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1UM6
 | | catalytic antibody 21h3 | | Descriptor: | antibody 21h3, H chain, L chain | | Authors: | Beuscher IV, A.E, Reuter, J, Olson, A.J, Romesberg, F.E, Schultz, P.G, Wirsching, P, Janda, K.D, Lerner, R.A, Stevens, R.C. | | Deposit date: | 2003-09-23 | | Release date: | 2004-10-05 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural Studies of an Efficient Catalytic Antibody Operating by Ping-Pong and Induced Fit Mechanisms
To be Published
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1UM5
 | | Catalytic Antibody 21H3 with alcohol substrate | | Descriptor: | 1-PHENYLETHANOL, Antibody 21H3 H chain, Antibody 21H3 L chain | | Authors: | Beuscher IV, A.E, Reuter, J, Olson, A.J, Romesberg, F.E, Schultz, P.G, Wirsching, P, Janda, K.D, Lerner, R.A, Stevens, R.C. | | Deposit date: | 2003-09-23 | | Release date: | 2004-10-05 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural Studies of an Efficient Catalytic Antibody Operating by Ping-Pong and Induced Fit Mechanisms
To be Published
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1A4J
 | | DIELS ALDER CATALYTIC ANTIBODY GERMLINE PRECURSOR | | Descriptor: | IMMUNOGLOBULIN, DIELS ALDER CATALYTIC ANTIBODY (HEAVY CHAIN), DIELS ALDER CATALYTIC ANTIBODY (LIGHT CHAIN) | | Authors: | Spiller, B.W, Romesburg, F.E, Schultz, P.G, Stevens, R.C. | | Deposit date: | 1998-01-30 | | Release date: | 1998-05-13 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Immunological origins of binding and catalysis in a Diels-Alderase antibody.
Science, 279, 1998
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1NGX
 | | Chimeric Germline Fab 7g12 with jeffamine fragment bound | | Descriptor: | Germline Metal Chelatase Catalytic Antibody, Heavy chain, Light chain, ... | | Authors: | Yin, J, Andryski, S.E, Beuscher, A.B, Stevens, R.C, Schultz, P.G. | | Deposit date: | 2002-12-18 | | Release date: | 2003-03-18 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural evidence for substrate strain in antibody catalysis
Proc.Natl.Acad.Sci.USA, 100, 2003
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1N7M
 | | Germline 7G12 with N-methylmesoporphyrin | | Descriptor: | Germline Metal Chelatase Catalytic Antibody, chain H, chain L, ... | | Authors: | Yin, J, Andryski, S.E, Beuscher IV, A.E, Stevens, R.C, Schultz, P.G. | | Deposit date: | 2002-11-15 | | Release date: | 2003-02-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural evidence for substrate strain in antibody catalysis
Proc.Natl.Acad.Sci.USA, 100, 2003
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1NGW
 | | Chimeric Affinity Matured Fab 7g12 complexed with mesoporphyrin | | Descriptor: | Mature Metal Chelatase Catalytic Antibody, Heavy chain, Light chain, ... | | Authors: | Yin, J, Andryski, S.E, Beuscher IV, A.E, Stevens, R.C, Schultz, P.G. | | Deposit date: | 2002-12-18 | | Release date: | 2003-02-04 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural evidence for substrate strain in antibody catalysis
Proc.Natl.Acad.Sci.USA, 100, 2003
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1NGZ
 | | Chimeric Germline Fab 7g12-apo | | Descriptor: | Germline Metal Chelatase Catalytic Antibody, Heavy chain, Light chain | | Authors: | Yin, J, Andryski, S.A, Beuscher, A.B, Stevens, R.C, Schultz, P.G. | | Deposit date: | 2002-12-18 | | Release date: | 2003-02-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural evidence for substrate strain in antibody catalysis
Proc.Natl.Acad.Sci.USA, 100, 2003
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1MRB
 | | THREE-DIMENSIONAL STRUCTURE OF RABBIT LIVER CD7 METALLOTHIONEIN-2A IN AQUEOUS SOLUTION DETERMINED BY NUCLEAR MAGNETIC RESONANCE | | Descriptor: | CADMIUM ION, CD7 METALLOTHIONEIN-2A | | Authors: | Braun, W, Arseniev, A, Schultze, P, Woergoetter, E, Wagner, G, Vasak, M, Kaegi, J.H.R, Wuthrich, K. | | Deposit date: | 1990-05-14 | | Release date: | 1991-04-15 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Three-dimensional structure of rabbit liver [Cd7]metallothionein-2a in aqueous solution determined by nuclear magnetic resonance.
J.Mol.Biol., 201, 1988
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1NGY
 | | Chimeric Mature Fab 7g12-Apo | | Descriptor: | Mature Metal Chelatase Catalytic Antibody, Heavy chain, Light chain | | Authors: | Yin, J, Andryski, S.A, Beuscher, A.B, Stevens, R.C, Schultz, P.G. | | Deposit date: | 2002-12-18 | | Release date: | 2003-02-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural evidence for substrate strain in antibody catalysis
Proc.Natl.Acad.Sci.USA, 100, 2003
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1U7D
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1U7X
 | | crystal structure of a mutant M. jannashii tyrosyl-tRNA synthetase specific for O-methyl-tyrosine | | Descriptor: | POTASSIUM ION, Tyrosyl-tRNA synthetase | | Authors: | Zhang, Y, Wang, L, Schultz, P.G, Wilson, I.A. | | Deposit date: | 2004-08-04 | | Release date: | 2005-05-24 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structures of apo wild-type M. jannaschii tyrosyl-tRNA synthetase (TyrRS) and an engineered TyrRS specific for O-methyl-L-tyrosine.
Protein Sci., 14, 2005
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