1NGX

Chimeric Germline Fab 7g12 with jeffamine fragment bound

Summary for 1NGX

• Entry DOI: 10.2210/pdb1ngx/pdb
• Related: 1N7M 1NGW 1NGY 1NGZ 3FCT
• Descriptor: Germline Metal Chelatase Catalytic Antibody, Light chain, Germline Metal Chelatase Catalytic Antibody, Heavy chain, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500), ... (4 entities in total)
• Functional Keywords: antibody, immunoglobulin, antigen binding fragment (fab), immune system
• Biological source: Mus musculus, Homo sapiens (house mouse, human); More
• Total number of polymer chains: 4
• Total formula weight: 94083.41

Authors

Yin, J.,Andryski, S.E.,Beuscher, A.B.,Stevens, R.C.,Schultz, P.G. (deposition date: 2002-12-18, release date: 2003-03-18, Last modification date: 2018-01-31)

• Primary citation: Yin, J.,Andryski, S.E.,Beuscher, A.B.,Stevens, R.C.,Schultz, P.G.; Structural evidence for substrate strain in antibody catalysis; Proc.Natl.Acad.Sci.USA, 100:856-861, 2003; PubMed: 12552112; DOI: 10.1073/pnas.0235873100

Experimental method

X-RAY DIFFRACTION (1.8 Å)