1NGW
Chimeric Affinity Matured Fab 7g12 complexed with mesoporphyrin
Summary for 1NGW
| Entry DOI | 10.2210/pdb1ngw/pdb |
| Related | 1N7M 3FCT |
| Descriptor | Mature Metal Chelatase Catalytic Antibody, Light chain, Mature Metal Chelatase Catalytic Antibody, Heavy chain, N-METHYLMESOPORPHYRIN, ... (4 entities in total) |
| Functional Keywords | antibody, immunoglobulin, antigen binding fragment, immune system |
| Biological source | Mus musculus, Homo sapiens (house mouse, human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 94219.61 |
| Authors | Yin, J.,Andryski, S.E.,Beuscher IV, A.E.,Stevens, R.C.,Schultz, P.G. (deposition date: 2002-12-18, release date: 2003-02-04, Last modification date: 2018-01-31) |
| Primary citation | Yin, J.,Andryski, S.E.,Beuscher IV, A.E.,Stevens, R.C.,Schultz, P.G. Structural evidence for substrate strain in antibody catalysis Proc.Natl.Acad.Sci.USA, 100:856-861, 2003 Cited by PubMed: 12552112DOI: 10.1073/pnas.0235873100 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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