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PDB: 7 results
4LEO
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BU of 4leo by Molmil
Crystal structure of anti-HER3 Fab RG7116 in complex with the extracellular domains of human Her3 (ERBB3)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RG7116 Fab heavy chain, ...
Authors:Schiller, C.B, Hopfner, K.P.
Deposit date:2013-06-26
Release date:2013-07-10
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:RG7116, a Therapeutic Antibody That Binds the Inactive HER3 Receptor and Is Optimized for Immune Effector Activation.
Cancer Res., 73, 2013
4FCX
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BU of 4fcx by Molmil
S.pombe Mre11 apoenzym
Descriptor: DNA repair protein rad32, MANGANESE (II) ION
Authors:Schiller, C.B, Lammens, K, Hopfner, K.P.
Deposit date:2012-05-25
Release date:2012-06-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of Mre11-Nbs1 complex yields insights into ataxia-telangiectasia-like disease mutations and DNA damage signaling.
Nat.Struct.Mol.Biol., 19, 2012
4FBW
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BU of 4fbw by Molmil
Crystal structure of an unfused Mre11-Nbs1 complex with two manganese ions per active site
Descriptor: DNA repair and telomere maintenance protein nbs1, DNA repair protein rad32, MANGANESE (II) ION
Authors:Schiller, C.B, Lammens, K, Hopfner, K.P.
Deposit date:2012-05-23
Release date:2012-06-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Mre11-Nbs1 complex yields insights into ataxia-telangiectasia-like disease mutations and DNA damage signaling.
Nat.Struct.Mol.Biol., 19, 2012
4FBQ
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BU of 4fbq by Molmil
Crystal structure of a covalently fused Nbs1-Mre11 complex with two manganese ions per active site
Descriptor: DNA repair and telomere maintenance protein nbs1,DNA repair protein rad32 CHIMERIC PROTEIN, MANGANESE (II) ION
Authors:Schiller, C.B, Lammens, K, Hopfner, K.P.
Deposit date:2012-05-23
Release date:2012-06-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of Mre11-Nbs1 complex yields insights into ataxia-telangiectasia-like disease mutations and DNA damage signaling.
Nat.Struct.Mol.Biol., 19, 2012
4FBK
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BU of 4fbk by Molmil
Crystal structure of a covalently fused Nbs1-Mre11 complex with one manganese ion per active site
Descriptor: DNA repair and telomere maintenance protein nbs1,DNA repair protein rad32 CHIMERIC PROTEIN, MANGANESE (II) ION, SULFATE ION
Authors:Schiller, C.B, Lammens, K, Hopfner, K.P.
Deposit date:2012-05-23
Release date:2012-06-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.379 Å)
Cite:Structure of Mre11-Nbs1 complex yields insights into ataxia-telangiectasia-like disease mutations and DNA damage signaling.
Nat.Struct.Mol.Biol., 19, 2012
4IMK
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BU of 4imk by Molmil
Uncrossed Fab binding to human Angiopoietin 2
Descriptor: GLYCEROL, Heavy Chain, Light Chain, ...
Authors:Fenn, S, Schiller, C, Griese, J.J, Hopfner, K.-P, Kettenberger, H.
Deposit date:2013-01-03
Release date:2013-04-17
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (2.202 Å)
Cite:Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain.
Plos One, 8, 2013
4IML
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BU of 4iml by Molmil
CrossFab binding to human Angiopoietin 2
Descriptor: Crossed heavy chain (VH-Ckappa), Crossed light chain (VL-CH1), GLYCEROL
Authors:Fenn, S, Schiller, C, Griese, J, Hopfner, K.-P, Kettenberger, H.
Deposit date:2013-01-03
Release date:2013-04-17
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (2.931 Å)
Cite:Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain.
Plos One, 8, 2013

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