3BPX
| Crystal Structure of MarR | Descriptor: | 2-HYDROXYBENZOIC ACID, SODIUM ION, Transcriptional regulator | Authors: | Saridakis, V, Shahinas, D, Xu, X, Christendat, D. | Deposit date: | 2007-12-19 | Release date: | 2008-05-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural insight on the mechanism of regulation of the MarR family of proteins: high-resolution crystal structure of a transcriptional repressor from Methanobacterium thermoautotrophicum. J.Mol.Biol., 377, 2008
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1HYB
| CRYSTAL STRUCTURE OF AN ACTIVE SITE MUTANT OF METHANOBACTERIUM THERMOAUTOTROPHICUM NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE | Descriptor: | BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE, SULFATE ION | Authors: | Saridakis, V, Christendat, D, Kimber, M.S, Edwards, A.M, Pai, E.F. | Deposit date: | 2001-01-18 | Release date: | 2001-03-14 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Insights into ligand binding and catalysis of a central step in NAD+ synthesis: structures of Methanobacterium thermoautotrophicum NMN adenylyltransferase complexes. J.Biol.Chem., 276, 2001
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6P5L
| Crystal Structure of Ubl123 with an EZH2 peptide | Descriptor: | PRO-ARG-LYS-LYS-LYS-ARG-LYS-HIS, Ubiquitin carboxyl-terminal hydrolase 7 | Authors: | Saridakis, V. | Deposit date: | 2019-05-30 | Release date: | 2020-05-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.296 Å) | Cite: | Structural Basis of the Interaction Between Ubiquitin Specific Protease 7 and Enhancer of Zeste Homolog 2. J.Mol.Biol., 432, 2020
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3MQR
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3MQS
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1YY6
| The Crystal Structure of the N-terminal domain of HAUSP/USP7 complexed with an EBNA1 peptide | Descriptor: | Epstein-Barr nuclear antigen-1, SODIUM ION, Ubiquitin carboxyl-terminal hydrolase 7 | Authors: | Saridakis, V, Sheng, Y, Sarkari, F, Holowaty, M, Shire, K, Nguyen, T, Zhang, R, Liao, J, Lee, W, Edwards, A.M, Arrowsmith, C.H, Frappier, L. | Deposit date: | 2005-02-23 | Release date: | 2005-04-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization. Mol.Cell, 18, 2005
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1YZE
| Crystal structure of the N-terminal domain of USP7/HAUSP. | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 7 | Authors: | Saridakis, V, Sheng, Y, Sarkari, F, Holowaty, M.N, Shire, K, Nguyen, T, Zhang, R.G, Liao, J, Lee, W, Edwards, A.M, Arrowsmith, C.H, Frappier, L. | Deposit date: | 2005-02-28 | Release date: | 2005-04-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization. Mol.Cell, 18, 2005
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3BPV
| Crystal Structure of MarR | Descriptor: | Transcriptional regulator | Authors: | Saridakis, V, Shahinas, D, Xu, X, Christendat, D. | Deposit date: | 2007-12-19 | Release date: | 2008-05-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural insight on the mechanism of regulation of the MarR family of proteins: high-resolution crystal structure of a transcriptional repressor from Methanobacterium thermoautotrophicum. J.Mol.Biol., 377, 2008
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2FOJ
| The Crystal Structure of the N-terminal domain of HAUSP/USP7 complexed with p53 peptide 364-367 | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 7, p53 peptide | Authors: | Saridakis, V, Sheng, Y, Sarkari, F, Duan, S, Wu, T, Arrowsmith, C.H, Frappier, L. | Deposit date: | 2006-01-13 | Release date: | 2006-02-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Molecular recognition of p53 and MDM2 by USP7/HAUSP Nat.Struct.Mol.Biol., 13, 2006
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2FOP
| The Crystal Structure of the N-terminal domain of HAUSP/USP7 complexed with mdm2 peptide 147-150 | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 7, mdm2 peptide | Authors: | Saridakis, V, Sheng, Y, Sarkari, F, Duan, S, Wu, T, Arrowsmith, C.H, Frappier, L. | Deposit date: | 2006-01-13 | Release date: | 2006-02-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular recognition of p53 and MDM2 by USP7/HAUSP Nat.Struct.Mol.Biol., 13, 2006
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2FOO
| The Crystal Structure of the N-terminal domain of HAUSP/USP7 complexed with p53 peptide 359-362 | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 7, p53 peptide | Authors: | Saridakis, V, Sheng, Y, Sarkari, F, Duan, S, Wu, T, Arrowsmith, C.H, Frappier, L. | Deposit date: | 2006-01-13 | Release date: | 2006-02-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Molecular recognition of p53 and MDM2 by USP7/HAUSP Nat.Struct.Mol.Biol., 13, 2006
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1KUU
| CRYSTAL STRUCTURE OF METHANOBACTERIUM THERMOAUTOTROPHICUM CONSERVED PROTEIN MTH1020 REVEALS AN NTN-HYDROLASE FOLD | Descriptor: | conserved protein | Authors: | Saridakis, V, Christendat, D, Thygesen, A, Arrowsmith, C.H, Edwards, A.M, Pai, E.F. | Deposit date: | 2002-01-22 | Release date: | 2002-05-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | CRYSTAL STRUCTURE OF METHANOBACTERIUM THERMOAUTOTROPHICUM CONSERVED PROTEIN MTH1020 REVEALS AN NTN-HYDROLASE FOLD PROTEINS: STRUCT.,FUNCT.,GENET., 48, 2002
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1M8K
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1M8F
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4JJQ
| Crystal structure of usp7-ntd with an e2 enzyme | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 7, Ubiquitin-conjugating enzyme E2 E1 | Authors: | Saridakis, V. | Deposit date: | 2013-03-08 | Release date: | 2013-05-01 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Ubiquitin-specific protease 7 is a regulator of ubiquitin-conjugating enzyme UbE2E1. J. Biol. Chem., 288, 2013
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1NOG
| Crystal Structure of Conserved Protein 0546 from Thermoplasma Acidophilum | Descriptor: | conserved hypothetical protein TA0546 | Authors: | Saridakis, V, Sanishvili, R, Iakounine, A, Xu, X, Pennycooke, M, Gu, J, Joachimiak, A, Arrowsmith, C.H, Edwards, A.M, Christendat, D, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2003-01-16 | Release date: | 2003-07-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | The structural basis for methylmalonic aciduria. The crystal structure of archaeal ATP:cobalamin adenosyltransferase. J.Biol.Chem., 279, 2004
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4KG9
| Crystal Structure Of USP7-NTD with MCM-BP | Descriptor: | Mini-chromosome maintenance complex-binding protein, Ubiquitin carboxyl-terminal hydrolase 7 | Authors: | Saridakis, V, Luthra, N. | Deposit date: | 2013-04-29 | Release date: | 2013-11-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A role for USP7 in DNA replication. Mol.Cell.Biol., 34, 2014
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1M8J
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1M8G
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1EJ2
| Crystal structure of methanobacterium thermoautotrophicum nicotinamide mononucleotide adenylyltransferase with bound NAD+ | Descriptor: | NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION, ... | Authors: | Saridakis, V, Christendat, D, Kimber, M.S, Edwards, A.M, Pai, E.F, Midwest Center for Structural Genomics (MCSG), Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2000-02-29 | Release date: | 2001-03-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Insights into ligand binding and catalysis of a central step in NAD+ synthesis: structures of Methanobacterium thermoautotrophicum NMN adenylyltransferase complexes. J.Biol.Chem., 276, 2001
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1R6X
| The Crystal Structure of a Truncated Form of Yeast ATP Sulfurylase, Lacking the C-Terminal APS Kinase-like Domain, in complex with Sulfate | Descriptor: | ATP:sulfate adenylyltransferase, COBALT (II) ION, SULFATE ION | Authors: | Lalor, D.J, Schnyder, T, Saridakis, V, Pilloff, D.E, Dong, A, Tang, H, Leyh, T.S, Pai, E.F. | Deposit date: | 2003-10-17 | Release date: | 2003-11-11 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural and functional analysis of a truncated form of Saccharomyces cerevisiae ATP sulfurylase: C-terminal domain essential for oligomer formation but not for activity Protein Eng., 16, 2003
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1T57
| Crystal Structure of the Conserved Protein MTH1675 from Methanobacterium thermoautotrophicum | Descriptor: | Conserved Protein MTH1675, FLAVIN MONONUCLEOTIDE, MAGNESIUM ION | Authors: | Kim, Y, Joachimiak, A, Saridakis, V, Xu, X, Arrowsmith, C.H, Christendat, D, Edwards, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2004-05-03 | Release date: | 2004-08-03 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of the Conserved Protein MTH1675 from Methanobacterium thermoautotrophicum To be Published
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4WPH
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4WPI
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5L1M
| CASKIN2 SAM domain tandem | Descriptor: | Caskin-2 | Authors: | Donaldson, L.W, Kwan, J.J, Saridakis, V. | Deposit date: | 2016-07-29 | Release date: | 2016-08-10 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.751 Å) | Cite: | A new mode of SAM domain mediated oligomerization observed in the CASKIN2 neuronal scaffolding protein. Cell Commun. Signal, 14, 2016
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