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PDB: 36 results

3BPX
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BU of 3bpx by Molmil
Crystal Structure of MarR
Descriptor: 2-HYDROXYBENZOIC ACID, SODIUM ION, Transcriptional regulator
Authors:Saridakis, V, Shahinas, D, Xu, X, Christendat, D.
Deposit date:2007-12-19
Release date:2008-05-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural insight on the mechanism of regulation of the MarR family of proteins: high-resolution crystal structure of a transcriptional repressor from Methanobacterium thermoautotrophicum.
J.Mol.Biol., 377, 2008
1HYB
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BU of 1hyb by Molmil
CRYSTAL STRUCTURE OF AN ACTIVE SITE MUTANT OF METHANOBACTERIUM THERMOAUTOTROPHICUM NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE
Descriptor: BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE, SULFATE ION
Authors:Saridakis, V, Christendat, D, Kimber, M.S, Edwards, A.M, Pai, E.F.
Deposit date:2001-01-18
Release date:2001-03-14
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Insights into ligand binding and catalysis of a central step in NAD+ synthesis: structures of Methanobacterium thermoautotrophicum NMN adenylyltransferase complexes.
J.Biol.Chem., 276, 2001
6P5L
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Crystal Structure of Ubl123 with an EZH2 peptide
Descriptor: PRO-ARG-LYS-LYS-LYS-ARG-LYS-HIS, Ubiquitin carboxyl-terminal hydrolase 7
Authors:Saridakis, V.
Deposit date:2019-05-30
Release date:2020-05-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.296 Å)
Cite:Structural Basis of the Interaction Between Ubiquitin Specific Protease 7 and Enhancer of Zeste Homolog 2.
J.Mol.Biol., 432, 2020
3MQR
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Crystal Structure of the USP7:HdmX(AHSS) complex
Descriptor: HdmX Peptide, Ubiquitin carboxyl-terminal hydrolase 7
Authors:Saridakis, V.
Deposit date:2010-04-28
Release date:2010-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure Of USP7
To be Published
3MQS
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BU of 3mqs by Molmil
Crystal Structure of the USP7:Hdm2(PSTS) complex
Descriptor: Hdm2 peptide, Ubiquitin carboxyl-terminal hydrolase 7
Authors:Saridakis, V.
Deposit date:2010-04-28
Release date:2010-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of USP7
To be Published
1YY6
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BU of 1yy6 by Molmil
The Crystal Structure of the N-terminal domain of HAUSP/USP7 complexed with an EBNA1 peptide
Descriptor: Epstein-Barr nuclear antigen-1, SODIUM ION, Ubiquitin carboxyl-terminal hydrolase 7
Authors:Saridakis, V, Sheng, Y, Sarkari, F, Holowaty, M, Shire, K, Nguyen, T, Zhang, R, Liao, J, Lee, W, Edwards, A.M, Arrowsmith, C.H, Frappier, L.
Deposit date:2005-02-23
Release date:2005-04-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization.
Mol.Cell, 18, 2005
1YZE
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BU of 1yze by Molmil
Crystal structure of the N-terminal domain of USP7/HAUSP.
Descriptor: Ubiquitin carboxyl-terminal hydrolase 7
Authors:Saridakis, V, Sheng, Y, Sarkari, F, Holowaty, M.N, Shire, K, Nguyen, T, Zhang, R.G, Liao, J, Lee, W, Edwards, A.M, Arrowsmith, C.H, Frappier, L.
Deposit date:2005-02-28
Release date:2005-04-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization.
Mol.Cell, 18, 2005
3BPV
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BU of 3bpv by Molmil
Crystal Structure of MarR
Descriptor: Transcriptional regulator
Authors:Saridakis, V, Shahinas, D, Xu, X, Christendat, D.
Deposit date:2007-12-19
Release date:2008-05-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural insight on the mechanism of regulation of the MarR family of proteins: high-resolution crystal structure of a transcriptional repressor from Methanobacterium thermoautotrophicum.
J.Mol.Biol., 377, 2008
2FOJ
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BU of 2foj by Molmil
The Crystal Structure of the N-terminal domain of HAUSP/USP7 complexed with p53 peptide 364-367
Descriptor: Ubiquitin carboxyl-terminal hydrolase 7, p53 peptide
Authors:Saridakis, V, Sheng, Y, Sarkari, F, Duan, S, Wu, T, Arrowsmith, C.H, Frappier, L.
Deposit date:2006-01-13
Release date:2006-02-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Molecular recognition of p53 and MDM2 by USP7/HAUSP
Nat.Struct.Mol.Biol., 13, 2006
2FOP
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BU of 2fop by Molmil
The Crystal Structure of the N-terminal domain of HAUSP/USP7 complexed with mdm2 peptide 147-150
Descriptor: Ubiquitin carboxyl-terminal hydrolase 7, mdm2 peptide
Authors:Saridakis, V, Sheng, Y, Sarkari, F, Duan, S, Wu, T, Arrowsmith, C.H, Frappier, L.
Deposit date:2006-01-13
Release date:2006-02-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular recognition of p53 and MDM2 by USP7/HAUSP
Nat.Struct.Mol.Biol., 13, 2006
2FOO
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BU of 2foo by Molmil
The Crystal Structure of the N-terminal domain of HAUSP/USP7 complexed with p53 peptide 359-362
Descriptor: Ubiquitin carboxyl-terminal hydrolase 7, p53 peptide
Authors:Saridakis, V, Sheng, Y, Sarkari, F, Duan, S, Wu, T, Arrowsmith, C.H, Frappier, L.
Deposit date:2006-01-13
Release date:2006-02-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular recognition of p53 and MDM2 by USP7/HAUSP
Nat.Struct.Mol.Biol., 13, 2006
1KUU
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BU of 1kuu by Molmil
CRYSTAL STRUCTURE OF METHANOBACTERIUM THERMOAUTOTROPHICUM CONSERVED PROTEIN MTH1020 REVEALS AN NTN-HYDROLASE FOLD
Descriptor: conserved protein
Authors:Saridakis, V, Christendat, D, Thygesen, A, Arrowsmith, C.H, Edwards, A.M, Pai, E.F.
Deposit date:2002-01-22
Release date:2002-05-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:CRYSTAL STRUCTURE OF METHANOBACTERIUM THERMOAUTOTROPHICUM CONSERVED PROTEIN MTH1020 REVEALS AN NTN-HYDROLASE FOLD
PROTEINS: STRUCT.,FUNCT.,GENET., 48, 2002
1M8K
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Crystal Structure Of Methanobacterium Thermoautotrophicum Nicotinamide Mononucleotide Adenylyltransferase Mutant H19A complexed with NAD
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Nicotinamide-nucleotide Adenylyltransferase, SULFATE ION
Authors:Saridakis, V, Pai, E.F.
Deposit date:2002-07-25
Release date:2003-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Mutational, Structural, and Kinetic Studies of the ATP-binding Site of Methanobacterium thermoautotrophicum Nicotinamide Mononucleotide Adenylyltransferase
J.Biol.Chem., 278, 2003
1M8F
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BU of 1m8f by Molmil
Crystal Structure Of Methanobacterium Thermoautotrophicum Nicotinamide Mononucleotide Adenylyltransferase Mutant R11A complexed with NAD
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, nicotinamide-nucleotide adenylyltransferase
Authors:Saridakis, V, Pai, E.F.
Deposit date:2002-07-24
Release date:2003-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mutational, Structural, and Kinetic Studies of the ATP-binding Site of Methanobacterium thermoautotrophicum Nicotinamide Mononucleotide Adenylyltransferase
J.Biol.Chem., 278, 2003
4JJQ
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BU of 4jjq by Molmil
Crystal structure of usp7-ntd with an e2 enzyme
Descriptor: Ubiquitin carboxyl-terminal hydrolase 7, Ubiquitin-conjugating enzyme E2 E1
Authors:Saridakis, V.
Deposit date:2013-03-08
Release date:2013-05-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Ubiquitin-specific protease 7 is a regulator of ubiquitin-conjugating enzyme UbE2E1.
J. Biol. Chem., 288, 2013
1NOG
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BU of 1nog by Molmil
Crystal Structure of Conserved Protein 0546 from Thermoplasma Acidophilum
Descriptor: conserved hypothetical protein TA0546
Authors:Saridakis, V, Sanishvili, R, Iakounine, A, Xu, X, Pennycooke, M, Gu, J, Joachimiak, A, Arrowsmith, C.H, Edwards, A.M, Christendat, D, Midwest Center for Structural Genomics (MCSG)
Deposit date:2003-01-16
Release date:2003-07-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The structural basis for methylmalonic aciduria. The crystal structure of archaeal ATP:cobalamin adenosyltransferase.
J.Biol.Chem., 279, 2004
4KG9
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BU of 4kg9 by Molmil
Crystal Structure Of USP7-NTD with MCM-BP
Descriptor: Mini-chromosome maintenance complex-binding protein, Ubiquitin carboxyl-terminal hydrolase 7
Authors:Saridakis, V, Luthra, N.
Deposit date:2013-04-29
Release date:2013-11-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A role for USP7 in DNA replication.
Mol.Cell.Biol., 34, 2014
1M8J
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BU of 1m8j by Molmil
Crystal Structure Of Methanobacterium Thermoautotrophicum Nicotinamide Mononucleotide Adenylyltransferase Mutant R136A complexed with NAD
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Nicotinamide-nucleotide Adenylyltransferase, SULFATE ION
Authors:Saridakis, V, Pai, E.F.
Deposit date:2002-07-25
Release date:2003-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mutational, Structural, and Kinetic Studies of the ATP-binding Site of Methanobacterium thermoautotrophicum Nicotinamide Mononucleotide Adenylyltransferase
J.Biol.Chem., 278, 2003
1M8G
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BU of 1m8g by Molmil
Crystal Structure Of Methanobacterium Thermoautotrophicum Nicotinamide Mononucleotide Adenylyltransferase Mutant R11K complexed with NAD
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Nicotinamide-nucleotide Adenylyltransferase
Authors:Saridakis, V, Pai, E.F.
Deposit date:2002-07-24
Release date:2003-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mutational, Structural, and Kinetic Studies of the ATP-binding Site of Methanobacterium thermoautotrophicum Nicotinamide Mononucleotide Adenylyltransferase
J.Biol.Chem., 278, 2003
1EJ2
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BU of 1ej2 by Molmil
Crystal structure of methanobacterium thermoautotrophicum nicotinamide mononucleotide adenylyltransferase with bound NAD+
Descriptor: NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION, ...
Authors:Saridakis, V, Christendat, D, Kimber, M.S, Edwards, A.M, Pai, E.F, Midwest Center for Structural Genomics (MCSG), Northeast Structural Genomics Consortium (NESG)
Deposit date:2000-02-29
Release date:2001-03-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Insights into ligand binding and catalysis of a central step in NAD+ synthesis: structures of Methanobacterium thermoautotrophicum NMN adenylyltransferase complexes.
J.Biol.Chem., 276, 2001
1R6X
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BU of 1r6x by Molmil
The Crystal Structure of a Truncated Form of Yeast ATP Sulfurylase, Lacking the C-Terminal APS Kinase-like Domain, in complex with Sulfate
Descriptor: ATP:sulfate adenylyltransferase, COBALT (II) ION, SULFATE ION
Authors:Lalor, D.J, Schnyder, T, Saridakis, V, Pilloff, D.E, Dong, A, Tang, H, Leyh, T.S, Pai, E.F.
Deposit date:2003-10-17
Release date:2003-11-11
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural and functional analysis of a truncated form of Saccharomyces cerevisiae ATP sulfurylase: C-terminal domain essential for oligomer formation but not for activity
Protein Eng., 16, 2003
1T57
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BU of 1t57 by Molmil
Crystal Structure of the Conserved Protein MTH1675 from Methanobacterium thermoautotrophicum
Descriptor: Conserved Protein MTH1675, FLAVIN MONONUCLEOTIDE, MAGNESIUM ION
Authors:Kim, Y, Joachimiak, A, Saridakis, V, Xu, X, Arrowsmith, C.H, Christendat, D, Edwards, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2004-05-03
Release date:2004-08-03
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of the Conserved Protein MTH1675 from Methanobacterium thermoautotrophicum
To be Published
4WPH
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BU of 4wph by Molmil
Crystal structure of USP7 ubiquitin-like domains in compact conformation
Descriptor: CHLORIDE ION, ICP0, Ubiquitin carboxyl-terminal hydrolase 7
Authors:Pfoh, R, Lacdao, I, Saridakis, V.
Deposit date:2014-10-18
Release date:2015-06-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Crystal Structure of USP7 Ubiquitin-like Domains with an ICP0 Peptide Reveals a Novel Mechanism Used by Viral and Cellular Proteins to Target USP7.
Plos Pathog., 11, 2015
4WPI
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BU of 4wpi by Molmil
Crystal structure of USP7 ubiquitin-like domains in extended conformation
Descriptor: CHLORIDE ION, ICP0, Ubiquitin carboxyl-terminal hydrolase 7
Authors:Pfoh, R, Lacdao, I.K.L, Saridakis, V.
Deposit date:2014-10-18
Release date:2015-06-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal Structure of USP7 Ubiquitin-like Domains with an ICP0 Peptide Reveals a Novel Mechanism Used by Viral and Cellular Proteins to Target USP7.
Plos Pathog., 11, 2015
5L1M
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BU of 5l1m by Molmil
CASKIN2 SAM domain tandem
Descriptor: Caskin-2
Authors:Donaldson, L.W, Kwan, J.J, Saridakis, V.
Deposit date:2016-07-29
Release date:2016-08-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.751 Å)
Cite:A new mode of SAM domain mediated oligomerization observed in the CASKIN2 neuronal scaffolding protein.
Cell Commun. Signal, 14, 2016

 

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