1YZE

Crystal structure of the N-terminal domain of USP7/HAUSP.

Summary for 1YZE

• Entry DOI: 10.2210/pdb1yze/pdb
• Related: 1YY6
• Descriptor: Ubiquitin carboxyl-terminal hydrolase 7 (2 entities in total)
• Functional Keywords: deubiquitinating enzyme, apo form, traf domain, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: Q93009
• Total number of polymer chains: 3
• Total formula weight: 54399.31

Authors

Saridakis, V.,Sheng, Y.,Sarkari, F.,Holowaty, M.N.,Shire, K.,Nguyen, T.,Zhang, R.G.,Liao, J.,Lee, W.,Edwards, A.M.,Arrowsmith, C.H.,Frappier, L. (deposition date: 2005-02-28, release date: 2005-04-05, Last modification date: 2024-02-14)

• Primary citation: Saridakis, V.,Sheng, Y.,Sarkari, F.,Holowaty, M.N.,Shire, K.,Nguyen, T.,Zhang, R.G.,Liao, J.,Lee, W.,Edwards, A.M.,Arrowsmith, C.H.,Frappier, L.; Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization.; Mol.Cell, 18:25-36, 2005; PubMed: 15808506; DOI: 10.1016/j.molcel.2005.02.029

Experimental method

X-RAY DIFFRACTION (2 Å)