4WPH
Crystal structure of USP7 ubiquitin-like domains in compact conformation
Summary for 4WPH
Entry DOI | 10.2210/pdb4wph/pdb |
Related | 4WPI |
Descriptor | Ubiquitin carboxyl-terminal hydrolase 7, ICP0, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | deubiquitinating (dub) enzyme, ubiquitin-like (ubl) domains, icp0 binding site, hausp, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 90450.07 |
Authors | Pfoh, R.,Lacdao, I.,Saridakis, V. (deposition date: 2014-10-18, release date: 2015-06-17, Last modification date: 2023-12-27) |
Primary citation | Pfoh, R.,Lacdao, I.K.,Georges, A.A.,Capar, A.,Zheng, H.,Frappier, L.,Saridakis, V. Crystal Structure of USP7 Ubiquitin-like Domains with an ICP0 Peptide Reveals a Novel Mechanism Used by Viral and Cellular Proteins to Target USP7. Plos Pathog., 11:e1004950-e1004950, 2015 Cited by PubMed: 26046769DOI: 10.1371/journal.ppat.1004950 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.92 Å) |
Structure validation
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