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PDB: 11 results

6XR7
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BU of 6xr7 by Molmil
Abl isoform 1b inactive1 state
Descriptor: Tyrosine-protein kinase ABL1
Authors:Xie, T, Saleh, T, Rossi, P, Kalodimos, C.G.
Deposit date:2020-07-11
Release date:2020-10-07
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Conformational states dynamically populated by a kinase determine its function.
Science, 370, 2020
6XR6
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BU of 6xr6 by Molmil
Abl 1b isoform active state
Descriptor: Tyrosine-protein kinase ABL1
Authors:Xie, T, Saleh, T, Rossi, P, Kalodimos, C.G.
Deposit date:2020-07-11
Release date:2020-10-07
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Conformational states dynamically populated by a kinase determine its function.
Science, 370, 2020
6XRG
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BU of 6xrg by Molmil
Abl 1b isoform inactive2 state
Descriptor: Tyrosine-protein kinase ABL1
Authors:Xie, T, Saleh, T, Rossi, P, Kalodimos, C.G.
Deposit date:2020-07-12
Release date:2020-10-07
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Conformational states dynamically populated by a kinase determine its function.
Science, 370, 2020
6AMW
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BU of 6amw by Molmil
Abl1b Regulatory Module 'Activating' conformation
Descriptor: Tyrosine-protein kinase ABL1
Authors:Kalodimos, C.G, Rossi, P, Saleh, T.
Deposit date:2017-08-11
Release date:2017-09-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Atomic view of the energy landscape in the allosteric regulation of Abl kinase.
Nat. Struct. Mol. Biol., 24, 2017
6AMV
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BU of 6amv by Molmil
Abl 1b Regulatory Module 'inhibiting state'
Descriptor: Tyrosine-protein kinase ABL1
Authors:Kalodimos, C.G, Saleh, T, Rossi, P.
Deposit date:2017-08-11
Release date:2017-09-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Atomic view of the energy landscape in the allosteric regulation of Abl kinase.
Nat. Struct. Mol. Biol., 24, 2017
2L3S
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BU of 2l3s by Molmil
Structure of the autoinhibited Crk
Descriptor: Autoinhibited Crk protein
Authors:Kalodimos, C.G, Sarkar, P, Saleh, T, Tzeng, S.R, Birge, R.
Deposit date:2010-09-21
Release date:2010-12-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis for regulation of the Crk signaling protein by a proline switch.
Nat.Chem.Biol., 7, 2011
2L3Q
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BU of 2l3q by Molmil
Structure of the prolyl trans isomer of the Crk Protein
Descriptor: Trans isomer of Crk protein
Authors:Kalodimos, C, Sarkar, P, Saleh, T, Tzeng, S, Birge, R.
Deposit date:2010-09-21
Release date:2010-12-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis for regulation of the Crk signaling protein by a proline switch.
Nat.Chem.Biol., 7, 2011
2LQN
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BU of 2lqn by Molmil
Solution structure of CRKL
Descriptor: Crk-like protein
Authors:Jankowski, W, Saleh, T, Kalodimos, C.
Deposit date:2012-03-09
Release date:2012-05-16
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII.
Nat.Chem.Biol., 8, 2012
2L3P
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BU of 2l3p by Molmil
Structure of the prolyl cis isomer of the Crk Protein
Descriptor: Cis isomer of Crk protein
Authors:Kalodimos, C.G, Sarkar, P, Saleh, T, Tzeng, S.R, Birge, R.
Deposit date:2010-09-21
Release date:2010-12-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis for regulation of the Crk signaling protein by a proline switch.
Nat.Chem.Biol., 7, 2011
2LQW
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BU of 2lqw by Molmil
Solution structure of phosphorylated CRKL
Descriptor: Crk-like protein
Authors:Jankowski, W, Saleh, T, Kalodimos, C.
Deposit date:2012-03-16
Release date:2012-05-16
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII.
Nat.Chem.Biol., 8, 2012
2MS4
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BU of 2ms4 by Molmil
Cyclophilin a complexed with a fragment of crk-ii
Descriptor: Peptide, Peptidyl-prolyl cis-trans isomerase A
Authors:Jankowski, W, Saleh, T, Rossi, P, Kalodimos, C.
Deposit date:2014-07-22
Release date:2015-09-09
Last modified:2016-02-03
Method:SOLUTION NMR
Cite:Cyclophilin A promotes cell migration via the Abl-Crk signaling pathway.
Nat.Chem.Biol., 12, 2016

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