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PDB: 24 results

1IB1
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CRYSTAL STRUCTURE OF THE 14-3-3 ZETA:SEROTONIN N-ACETYLTRANSFERASE COMPLEX
Descriptor: 14-3-3 ZETA ISOFORM, COA-S-ACETYL TRYPTAMINE, SEROTONIN N-ACETYLTRANSFERASE
Authors:Obsil, T, Ghirlando, R, Klein, D.C, Ganguly, S, Dyda, F.
Deposit date:2001-03-26
Release date:2001-05-02
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the 14-3-3zeta:serotonin N-acetyltransferase complex. a role for scaffolding in enzyme regulation.
Cell(Cambridge,Mass.), 105, 2001
3L2C
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Crystal Structure of the DNA Binding Domain of FOXO4 Bound to DNA
Descriptor: FOXO consensus binding sequence, minus strand, plus strand, ...
Authors:Boura, E, Silhan, J, Sulc, M, Brynda, J, Obsilova, V, Obsil, T.
Deposit date:2009-12-15
Release date:2009-12-29
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.868 Å)
Cite:Structure of the human FOXO4-DBD-DNA complex at 1.9 A resolution reveals new details of FOXO binding to the DNA
Acta Crystallogr.,Sect.D, 66, 2010
6QK8
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BU of 6qk8 by Molmil
Crystal structure of yeast 14-3-3 protein (Bmh1) from Saccharomyces cerevisiae with the Nha1p (yeast Na+/H+ antiporter) 14-3-3 binding motif Ser481
Descriptor: Na(+)/H(+) antiporter, Protein BMH1
Authors:Smidova, A, Obsil, T, Obsilova, V.
Deposit date:2019-01-28
Release date:2019-10-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.917 Å)
Cite:The activity of Saccharomyces cerevisiae Na+, K+/H+antiporter Nha1 is negatively regulated by 14-3-3 protein binding at serine 481.
Biochim Biophys Acta Mol Cell Res, 1866, 2019
8QGY
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Cryo-EM structure of C-terminally truncated Apoptosis signal-regulating kinase 1 (ASK1)
Descriptor: Mitogen-activated protein kinase kinase kinase 5
Authors:Kosek, D, Honzejkova, K, Obsilova, V, Obsil, T.
Deposit date:2023-09-06
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:The cryo-EM structure of ASK1 reveals an asymmetric architecture allosterically modulated by TRX1.
Elife, 13, 2024
7NMZ
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Structure of 14-3-3 eta in complex with Nedd4-2(335-455) containing two 14-3-3 binding motifs Ser342 and Ser448
Descriptor: 14-3-3 protein eta, E3 ubiquitin-protein ligase NEDD4-like
Authors:Pohl, P, Obsil, T, Obsilova, V.
Deposit date:2021-02-23
Release date:2021-07-21
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.303 Å)
Cite:14-3-3-protein regulates Nedd4-2 by modulating interactions between HECT and WW domains.
Commun Biol, 4, 2021
5M4A
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Neutral trehalase Nth1 from Saccharomyces cerevisiae in complex with trehalose
Descriptor: Neutral trehalase, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose
Authors:Smidova, A, Alblova, M, Obsilova, V, Obsil, T.
Deposit date:2016-10-18
Release date:2017-11-01
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular basis of the 14-3-3 protein-dependent activation of yeast neutral trehalase Nth1.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6GKG
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Structure of 14-3-3 gamma in complex with caspase-2 14-3-3 binding motif Ser164
Descriptor: 14-3-3 protein gamma, Caspase-2
Authors:Alblova, M, Obsil, T, Obsilova, V.
Deposit date:2018-05-20
Release date:2018-10-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.847 Å)
Cite:14-3-3 protein masks the nuclear localization sequence of caspase-2.
FEBS J., 285, 2018
5JTA
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Neutral trehalase Nth1 from Saccharomyces cerevisiae
Descriptor: Neutral trehalase
Authors:Alblova, M, Smidova, A, Obsilova, V, Obsil, T.
Deposit date:2016-05-09
Release date:2017-11-01
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Molecular basis of the 14-3-3 protein-dependent activation of yeast neutral trehalase Nth1.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6Y4K
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BU of 6y4k by Molmil
Crystal structure of human 14-3-3 gamma in complex with CaMKK2 14-3-3 binding motif Ser100 and Fusicoccin A
Descriptor: 14-3-3 protein gamma, Calcium/calmodulin-dependent protein kinase kinase 2, FUSICOCCIN
Authors:Lentini Santo, D, Obsilova, V, Obsil, T.
Deposit date:2020-02-21
Release date:2021-01-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Stabilization of Protein-Protein Interactions between CaMKK2 and 14-3-3 by Fusicoccins.
Acs Chem.Biol., 15, 2020
6Y6B
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BU of 6y6b by Molmil
Crystal structure of human 14-3-3 gamma in complex with CaMKK2 14-3-3 binding motif Ser100 and 16-OMe-Fusicoccin H
Descriptor: (2~{R},3~{S},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[[(1~{S},3~{R},6~{S},7~{S},8~{R},9~{R},10~{R},11~{R},14~{S})-14-(me thoxymethyl)-3,10-dimethyl-9-oxidanyl-6-propan-2-yl-8-tricyclo[9.3.0.0^{3,7}]tetradecanyl]oxy]oxane-3,4,5-triol, 14-3-3 protein gamma, Calcium/calmodulin-dependent protein kinase kinase 2
Authors:Lentini Santo, D, Obsilova, V, Obsil, T.
Deposit date:2020-02-26
Release date:2021-02-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:Stabilization of Protein-Protein Interactions between CaMKK2 and 14-3-3 by Fusicoccins.
Acs Chem.Biol., 15, 2020
6ZBT
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BU of 6zbt by Molmil
Structure of 14-3-3 gamma in complex with Nedd4-2 14-3-3 binding motif Ser342
Descriptor: 1,1,1,3,3,3-hexafluoropropan-2-ol, 14-3-3 protein gamma, E3 ubiquitin-protein ligase NEDD4-like
Authors:Joshi, R, Kalabova, D, Obsil, T, Obsilova, V.
Deposit date:2020-06-09
Release date:2021-07-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.79948521 Å)
Cite:14-3-3-protein regulates Nedd4-2 by modulating interactions between HECT and WW domains.
Commun Biol, 4, 2021
6ZC9
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BU of 6zc9 by Molmil
Structure of 14-3-3 gamma in complex with Nedd4-2 14-3-3 binding motif Ser448
Descriptor: 1,1,1,3,3,3-hexafluoropropan-2-ol, 14-3-3 protein gamma, E3 ubiquitin-protein ligase NEDD4-like
Authors:Pohl, P, Kalabova, D, Obsil, T, Obsilova, V.
Deposit date:2020-06-10
Release date:2021-07-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.89895988 Å)
Cite:14-3-3-protein regulates Nedd4-2 by modulating interactions between HECT and WW domains.
Commun Biol, 4, 2021
5NIS
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BU of 5nis by Molmil
Neutral trehalase Nth1 from Saccharomyces cerevisiae
Descriptor: Neutral trehalase
Authors:Alblova, M, Smidova, A, Obsilova, V, Obsil, T.
Deposit date:2017-03-27
Release date:2017-11-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.155 Å)
Cite:Molecular basis of the 14-3-3 protein-dependent activation of yeast neutral trehalase Nth1.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5N6N
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BU of 5n6n by Molmil
CRYSTAL STRUCTURE OF THE 14-3-3:NEUTRAL TREHALASE NTH1 COMPLEX
Descriptor: CALCIUM ION, Neutral trehalase, Protein BMH1, ...
Authors:Alblova, M, Smidova, A, Obsilova, V, Obsil, T.
Deposit date:2017-02-15
Release date:2017-11-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Molecular basis of the 14-3-3 protein-dependent activation of yeast neutral trehalase Nth1.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6GKF
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BU of 6gkf by Molmil
Structure of 14-3-3 gamma in complex with caspase-2 14-3-3 binding motif Ser139
Descriptor: 14-3-3 protein gamma, Caspase-2
Authors:Alblova, M, Obsil, T, Obsilova, V.
Deposit date:2018-05-20
Release date:2018-10-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.598 Å)
Cite:14-3-3 protein masks the nuclear localization sequence of caspase-2.
FEBS J., 285, 2018
7A6Y
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BU of 7a6y by Molmil
Structure of 14-3-3 gamma in complex with DAPK2 peptide stabilized by FC-A
Descriptor: 14-3-3 protein gamma, DAPK2 C-terminal peptide, FUSICOCCIN
Authors:Horvath, M, Obsilova, V, Obsil, T.
Deposit date:2020-08-27
Release date:2021-08-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:14-3-3 proteins inactivate DAPK2 by promoting its dimerization and protecting key regulatory phosphosites.
Commun Biol, 4, 2021
7A6R
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BU of 7a6r by Molmil
Structure of 14-3-3 gamma in complex with DAPK2 peptide containing the 14-3-3 binding motif
Descriptor: 14-3-3 protein gamma, DAPK2 C-terminal peptide
Authors:Horvath, M, Obsilova, V, Obsil, T.
Deposit date:2020-08-26
Release date:2021-08-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:14-3-3 proteins inactivate DAPK2 by promoting its dimerization and protecting key regulatory phosphosites.
Commun Biol, 4, 2021
6EWW
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BU of 6eww by Molmil
Structure of 14-3-3 zeta in complex with CaMKK2 14-3-3 binding motif
Descriptor: 14-3-3 protein zeta/delta, ARG-LYS-LEU-SEP-LEU-GLN-GLU-ARG
Authors:Lentini Santo, D, Obsilova, V, Obsil, T.
Deposit date:2017-11-06
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.679 Å)
Cite:14-3-3 protein directly interacts with the kinase domain of calcium/calmodulin-dependent protein kinase kinase (CaMKK2).
Biochim. Biophys. Acta, 1862, 2018
6S9K
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Structure of 14-3-3 gamma in complex with caspase-2 peptide containing 14-3-3 binding motif Ser139 and NLS
Descriptor: 1,1,1,3,3,3-hexafluoropropan-2-ol, 14-3-3 protein gamma, Caspase-2
Authors:Alblova, M, Obsil, T, Obsilova, V.
Deposit date:2019-07-15
Release date:2020-01-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:14-3-3 protein binding blocks the dimerization interface of caspase-2.
Febs J., 287, 2020
6SAD
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Structure of 14-3-3 gamma in complex with double phosphorylated caspase-2 peptide on Ser139 and Ser164
Descriptor: 14-3-3 protein gamma, Caspase-2
Authors:Kalabova, D, Obsil, T, Obsilova, V.
Deposit date:2019-07-16
Release date:2020-01-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.753 Å)
Cite:14-3-3 protein binding blocks the dimerization interface of caspase-2.
Febs J., 287, 2020
2OJ4
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BU of 2oj4 by Molmil
Crystal structure of RGS3 RGS domain
Descriptor: Regulator of G-protein signaling 3
Authors:Boura, E, Obsil, T.
Deposit date:2007-01-12
Release date:2007-01-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:14-3-3 protein interacts with and affects the structure of RGS domain of regulator of G protein signaling 3 (RGS3).
J.Struct.Biol., 170, 2010
6QVW
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BU of 6qvw by Molmil
Solution structure of the free FOXO1 DNA binding domain
Descriptor: Forkhead box protein O1
Authors:Psenakova, K, Obsil, T, Veverka, V, Obsilova, V, Kohoutova, K.
Deposit date:2019-03-05
Release date:2019-09-04
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Forkhead Domains of FOXO Transcription Factors Differ in both Overall Conformation and Dynamics.
Cells, 8, 2019
6EJL
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BU of 6ejl by Molmil
Structure of 14-3-3 zeta in complex with ASK1 14-3-3 binding motif
Descriptor: 14-3-3 protein zeta/delta, Mitogen-activated protein kinase kinase kinase 5
Authors:Petrvalska, O, Lentini Santo, D, Obsilova, V, Obsil, T.
Deposit date:2017-09-21
Release date:2017-11-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.382 Å)
Cite:Crystal structure of 14-3-3 zeta in complex with ASK1 14-3-3 binding motif
To Be Published
6FEL
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BU of 6fel by Molmil
Structure of 14-3-3 gamma in complex with CaMKK2 14-3-3 binding motif Ser511
Descriptor: 14-3-3 protein gamma, Calcium/calmodulin-dependent protein kinase kinase 2
Authors:Lentini Santo, D, Obsilova, V, Obsil, T.
Deposit date:2018-01-02
Release date:2018-01-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:14-3-3 protein directly interacts with the kinase domain of calcium/calmodulin-dependent protein kinase kinase (CaMKK2).
Biochim. Biophys. Acta, 1862, 2018

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