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PDB: 48 results

8D5B
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BU of 8d5b by Molmil
Crystal structure of human METTL1 in complex with SAH
Descriptor: CACODYLATE ION, CHLORIDE ION, GLYCEROL, ...
Authors:Raj, R, Babu, K, Nam, Y.
Deposit date:2022-06-04
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structures and mechanisms of tRNA methylation by METTL1-WDR4.
Nature, 613, 2023
8D59
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BU of 8d59 by Molmil
Crystal structure of human METTL1 in complex with SAM
Descriptor: CACODYLATE ION, CHLORIDE ION, GLYCEROL, ...
Authors:Raj, R, Babu, K, Nam, Y.
Deposit date:2022-06-04
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structures and mechanisms of tRNA methylation by METTL1-WDR4.
Nature, 613, 2023
5K7W
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BU of 5k7w by Molmil
Crystal structure of the catalytic domain of Mettl3/Mettl14 complex with SAH
Descriptor: N6-adenosine-methyltransferase 70 kDa subunit, N6-adenosine-methyltransferase subunit METTL14, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Wang, P, Doxtader, K.A, Nam, Y.
Deposit date:2016-05-26
Release date:2016-07-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases.
Mol.Cell, 63, 2016
8EG0
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BU of 8eg0 by Molmil
CryoEM structure of human METTL1-WDR4 in complex with Lys-tRNA and SAH
Descriptor: RNA (65-MER), S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine-N(7)-)-methyltransferase, ...
Authors:Ruiz-Arroyo, V.M, Nam, Y.
Deposit date:2022-09-10
Release date:2023-01-11
Last modified:2023-01-25
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Structures and mechanisms of tRNA methylation by METTL1-WDR4.
Nature, 613, 2023
8D58
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BU of 8d58 by Molmil
Crystal structure of human METTL1-WDR4 complex
Descriptor: CHLORIDE ION, GLYCEROL, ISOPROPYL ALCOHOL, ...
Authors:Raj, R, Babu, K, Nam, Y.
Deposit date:2022-06-04
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Structures and mechanisms of tRNA methylation by METTL1-WDR4.
Nature, 613, 2023
8D9K
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BU of 8d9k by Molmil
CryoEM structure of human METTL1-WDR4 in complex with Lys-tRNA
Descriptor: RNA (65-MER), tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4
Authors:Ruiz-Arroyo, V.M, Nam, Y.
Deposit date:2022-06-10
Release date:2023-01-11
Last modified:2023-01-25
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Structures and mechanisms of tRNA methylation by METTL1-WDR4.
Nature, 613, 2023
8D9L
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BU of 8d9l by Molmil
CryoEM structure of human METTL1-WDR4 in complex with Lys-tRNA and SAM
Descriptor: Lys-tRNA, S-ADENOSYLMETHIONINE, tRNA (guanine-N(7)-)-methyltransferase, ...
Authors:Ruiz-Arroyo, V.M, Nam, Y.
Deposit date:2022-06-10
Release date:2023-01-11
Last modified:2023-01-25
Method:ELECTRON MICROSCOPY (4.04 Å)
Cite:Structures and mechanisms of tRNA methylation by METTL1-WDR4.
Nature, 613, 2023
4WH2
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BU of 4wh2 by Molmil
N-acetylhexosamine 1-kinase in complex with ADP
Descriptor: ACETIC ACID, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ...
Authors:Sato, M, Arakawa, T, Nam, Y.W, Nishimoto, M, Kitaoka, M, Fushinobu, S.
Deposit date:2014-09-19
Release date:2015-02-18
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.847 Å)
Cite:Open-close structural change upon ligand binding and two magnesium ions required for the catalysis of N-acetylhexosamine 1-kinase
Biochim.Biophys.Acta, 1854, 2015
4WH1
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BU of 4wh1 by Molmil
N-Acetylhexosamine 1-kinase (ligand free)
Descriptor: ACETIC ACID, GLYCEROL, N-acetylhexosamine 1-kinase
Authors:Sato, M, Arakawa, T, Nam, Y.W, Nishimoto, M, Kitaoka, M, Fushinobu, S.
Deposit date:2014-09-19
Release date:2015-02-11
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Open-close structural change upon ligand binding and two magnesium ions required for the catalysis of N-acetylhexosamine 1-kinase
Biochim.Biophys.Acta, 1854, 2015
4WH3
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BU of 4wh3 by Molmil
N-acetylhexosamine 1-kinase in complex with ATP
Descriptor: ACETIC ACID, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ...
Authors:Sato, M, Arakawa, T, Nam, Y.W, Nishimoto, M, Kitaoka, M, Fushinobu, S.
Deposit date:2014-09-19
Release date:2015-02-18
Last modified:2020-02-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Open-close structural change upon ligand binding and two magnesium ions required for the catalysis of N-acetylhexosamine 1-kinase
Biochim.Biophys.Acta, 1854, 2015
7RX7
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BU of 7rx7 by Molmil
Structure of METTL3-METTL14(R298P) mutant methyltransferase complex
Descriptor: N6-adenosine-methyltransferase 70 kDa subunit, N6-adenosine-methyltransferase non-catalytic subunit
Authors:Wang, P, Nam, Y.
Deposit date:2021-08-21
Release date:2022-11-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.645 Å)
Cite:Structure of METTL3-METTL14(R298P) mutant methyltransferase complex
To Be Published
6UV1
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BU of 6uv1 by Molmil
Crystal structure of RNA helicase DDX17 in complex of rU10 RNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Ngo, T.D, Partin, A.C, Nam, Y.
Deposit date:2019-11-01
Release date:2020-01-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.307 Å)
Cite:RNA Specificity and Autoregulation of DDX17, a Modulator of MicroRNA Biogenesis.
Cell Rep, 29, 2019
6DU5
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BU of 6du5 by Molmil
Crystal structure of hMettl16 catalytic domain in complex with MAT2A 3'UTR hairpin 6
Descriptor: U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase, hp6-RNA (25-MER)
Authors:Doxtader, K, Wang, P, Nam, Y.
Deposit date:2018-06-19
Release date:2018-09-26
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (3.006 Å)
Cite:Structural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor.
Mol. Cell, 71, 2018
6DU4
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BU of 6du4 by Molmil
Crystal structure of hMettl16 catalytic domain in complex with MAT2A 3'UTR hairpin 1
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase, ...
Authors:Doxtader, K, Wang, P, Nam, Y.
Deposit date:2018-06-19
Release date:2018-09-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor.
Mol. Cell, 71, 2018
6UV4
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BU of 6uv4 by Molmil
Crystal structure of the core domain of RNA helicase DDX17 with RNA pri-18a-oligo1
Descriptor: 18a_oligo1, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Ngo, T.D, Partin, A.C, Nam, Y.
Deposit date:2019-11-01
Release date:2020-01-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:RNA Specificity and Autoregulation of DDX17, a Modulator of MicroRNA Biogenesis.
Cell Rep, 29, 2019
6UV3
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BU of 6uv3 by Molmil
Crystal structure of the core domain of RNA helicase DDX17 with RNA pri-125a-oligo2
Descriptor: 125a-oligo2, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Ngo, T.D, Partin, A.C, Nam, Y.
Deposit date:2019-11-01
Release date:2020-01-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.597 Å)
Cite:RNA Specificity and Autoregulation of DDX17, a Modulator of MicroRNA Biogenesis.
Cell Rep, 29, 2019
6UV0
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BU of 6uv0 by Molmil
Crystal structure of apo core domain of RNA helicase DDX17
Descriptor: MAGNESIUM ION, Probable ATP-dependent RNA helicase DDX17
Authors:Ngo, T.D, Partin, A.C, Nam, Y.
Deposit date:2019-11-01
Release date:2020-01-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:RNA Specificity and Autoregulation of DDX17, a Modulator of MicroRNA Biogenesis.
Cell Rep, 29, 2019
6UV2
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BU of 6uv2 by Molmil
Crystal structure of the core domain of RNA helicase DDX17 with RNA pri-125a-oligo1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Ngo, T.D, Partin, A.C, Nam, Y.
Deposit date:2019-11-01
Release date:2020-01-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.894 Å)
Cite:RNA Specificity and Autoregulation of DDX17, a Modulator of MicroRNA Biogenesis.
Cell Rep, 29, 2019
6V5C
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BU of 6v5c by Molmil
Human Drosha and DGCR8 in complex with Primary MicroRNA (MP/RNA complex) - partially docked state
Descriptor: Microprocessor complex subunit DGCR8, Pri-miR-16-2 (66-MER), Ribonuclease 3
Authors:Partin, A, Zhang, K, Jeong, B, Herrell, E, Li, S, Chiu, W, Nam, Y.
Deposit date:2019-12-04
Release date:2020-04-08
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Cryo-EM Structures of Human Drosha and DGCR8 in Complex with Primary MicroRNA.
Mol.Cell, 78, 2020
6V5B
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BU of 6v5b by Molmil
Human Drosha and DGCR8 in complex with Primary MicroRNA (MP/RNA complex) - Active state
Descriptor: CALCIUM ION, Microprocessor complex subunit DGCR8, Pri-miR-16-2 (78-MER), ...
Authors:Partin, A, Zhang, K, Jeong, B, Herrell, E, Li, S, Chiu, W, Nam, Y.
Deposit date:2019-12-04
Release date:2020-04-08
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM Structures of Human Drosha and DGCR8 in Complex with Primary MicroRNA.
Mol.Cell, 78, 2020
3PE4
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BU of 3pe4 by Molmil
Structure of human O-GlcNAc transferase and its complex with a peptide substrate
Descriptor: Casein kinase II subunit alpha, SULFATE ION, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, ...
Authors:Lazarus, M.B, Nam, Y, Jiang, J, Sliz, P, Walker, S.
Deposit date:2010-10-25
Release date:2011-01-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of human O-GlcNAc transferase and its complex with a peptide substrate.
Nature, 469, 2011
3PE3
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BU of 3pe3 by Molmil
Structure of human O-GlcNAc transferase and its complex with a peptide substrate
Descriptor: UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, URIDINE-5'-DIPHOSPHATE
Authors:Lazarus, M.B, Nam, Y, Jiang, J, Sliz, P, Walker, S.
Deposit date:2010-10-25
Release date:2011-01-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Structure of human O-GlcNAc transferase and its complex with a peptide substrate.
Nature, 469, 2011
3DIN
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BU of 3din by Molmil
Crystal structure of the protein-translocation complex formed by the SecY channel and the SecA ATPase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Zimmer, J, Nam, Y, Rapoport, T.A.
Deposit date:2008-06-20
Release date:2008-10-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structure of a complex of the ATPase SecA and the protein-translocation channel.
Nature, 455, 2008
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